Breeding for tolerance to worms for the future of sheep farming in England

为英国养羊业的未来培育抗蠕虫能力

• 批准号: 10034175
• 金额: $ 5.56万
• 依托单位: M & P SMITH- TREFRANCK FARM
• 依托单位国家: 英国
• 项目类别: Collaborative R&D
• 财政年份: 2022
• 资助国家: 英国
• 起止时间: 2022 至 无数据
• 项目状态: 已结题
• 来源: https://gtr.ukri.org/projects?ref=10034175
• 关键词: Breeding; tolerance; worms; future; sheep

We are studying the problem of parasitic gastroenteritis (gut worms) in sheep. We hope to aid UK farmers to farm more efficiently and have less environmental impact. In world where many wormer classes are not working sufficiently, we need to explore the growth rates and financial rewards that can be achieved by exploiting the genetic that can give sheep tolerance or resistance to worms. A study of 45 farms in the South West (1) recently found that around 94% of the average Farm Business Income was made up of the Basic Payment Scheme, which soon to be withdrawn. Anything we can be doing to farm more efficiently should therefore be considered.We run a farm in Cornwall with 800 breeding ewes and regularly pull genetics from the New Zealand flock by importing Rams. We hope to identify and exploit the genetic variation in some sheep which allows them to tolerate or be resistant to worms, whilst still growing sufficiently. Exploiting tolerance or resistance to worms could result in reducing farm labour for drenching, lowering treatment frequency and costs, increasing lamb growing efficiency whilst also improving sheep welfare and production.To test and identify tolerance or resistance, approximately 200 of the Trefrank Farm ram lamb crop (2022) will be weighed and have dung samples taken for faecal egg testing every 2 weeks from July - November. We aim to identify those lambs that can tolerate a high gastrointestinal worm burden whilst still maintaining adequate growth rates. A control group of 20 lambs will be wormed every 4 weeks to act as a 'control' by which to benchmark the test groups' growth rates. It is crucial that welfare is constantly assessed as measured by performance, and any test lambs dropping below 70% of the control group's growth rates will be drenched with a wormer.Results will be analyzed by scientists at the Moredun Institute and disseminated through CIEL. Alongside informing farmers practically, this study will increase the evidence-based knowledge for vets, researchers and also farmers. This approach to using genetics could potentially be replicated and also encourage others to consider tolerance as an important factor in a productive, welfare-driven flock.1. 'North Devon Pioneer Project' - Business Information Point, Devon

我们正在研究绵羊的寄生性肠胃炎（肠道蠕虫）问题。我们希望帮助英国农民更有效地耕作，减少对环境的影响。在一个许多工农阶级没有充分工作的世界里，我们需要探索通过开发能够使绵羊耐受或抵抗蠕虫的基因来实现的增长率和经济回报。一项对英国西南部45个农场的研究最近发现，大约94%的农场平均营业收入是由基本支付计划（Basic Payment Scheme）组成的，而该计划很快就会被取消。因此，我们应该考虑为提高农业效率所能做的任何事情。我们在康沃尔经营着一个农场，有800只母羊，并定期从新西兰羊群中进口公羊来获取基因。我们希望鉴定和利用某些绵羊的遗传变异，使它们能够耐受或抵抗蠕虫，同时仍能充分生长。利用对蠕虫的耐受性或抗性可以减少农场浇水的劳动力，降低治疗频率和成本，提高羔羊的生长效率，同时还可以改善羊的福利和产量。为了测试和确定耐受性或耐药性，将从7月至11月每两周对Trefrank农场（2022年）约200只公羊进行称重，并采集粪便样本进行粪蛋检测。我们的目标是确定那些能够忍受高胃肠道蠕虫负担的羔羊，同时仍然保持足够的生长速度。每4周将对20只羔羊进行一次驱虫，作为“对照”，以基准测试各组的生长速度。至关重要的是，福利是通过表现来持续评估的，任何低于对照组生长速度70%的测试羔羊都将被浇水。结果将由莫尔登研究所的科学家进行分析，并通过CIEL传播。除了向农民提供实际信息外，这项研究还将为兽医、研究人员和农民增加基于证据的知识。这种利用遗传学的方法有可能被复制，并鼓励其他人将宽容视为高产、福利驱动的羊群的一个重要因素。“北德文郡先锋项目”——德文郡商业信息点