Recruitment and Engagement Core

招聘与参与核心：摘要 许多美洲印第安人、阿拉斯加原住民（AI/AN）、夏威夷原住民和太平洋岛民（NHPI）社区 以怀疑、不信任甚至敌意的态度看待学术研究，部分原因是研究在历史上 在社区内或社区上进行，而不是在社区参与下进行。因此，社区知情 参与式方法已经成为人工智能/人工神经网络和国家卫生研究机构研究的首选模式，因为它们 核心价值观包括在伙伴之间公平分配权力和资源， 合作伙伴提供的知识。2013年，国家老龄问题研究所举办了一个讲习班， 作为国家应对阿尔茨海默病计划的一部分， 疾病一个优先事项是将差异人口纳入研究。然而，AI/AN和NHPI 尽管土著老年人的预期寿命显著增加，但这项工作在很大程度上忽视了这一点。为 例如，目前的32个阿尔茨海默病中心在过去的一年中只招募了110名AI/AN和19名NHPI。 7年（平均每个中心每2年1人），尽管现有建议增加多样性。 招募和参与核心将采用国家老龄问题研究所推荐的战略 在阿尔茨海默病和相关痴呆症（ADRD）研究中的招募和保留， 致力于创新和传统方法，使社区参与。这些战略包括： 由AI/AN和NHPI调查员领导的8个卫星中心组成的网络，代表了 学术和社区合作伙伴，这将扩大我们的工作超越我们的研究国家的影响 项目这些中心将评估研究准备情况，并通过新颖的“大脑训练”实践讲习班， 建立一个IRB批准的AI/AN和NHPI注册表，这些人希望参与ADRD研究。我们的具体 目的是：1）通过应用创新的方法来监测和评估研究项目的招聘和保留 战略，并确定ADRD外展和参与的最佳实践; 2）评估社区研究 通过卫星中心网络为未来的ADRD研究做好准备并定位AI/AN和NHPI站点 “脑训练”ADRD讲习班; 3）建立IRB批准的人工智能/人工神经元和国家精神卫生机构的研究和信息登记册 对ADRD研究感兴趣; 4）制作教育和招聘材料， ADRD供当地社区和国家场地的研究项目使用。这个核心将使用策略 旨在斯托克的兴趣研究和治疗进展，无论是在社区参与研究 确保利益攸关方参与生物标本的收集和传播， 结果AI/AN人口的增长速度是美国总人口的3倍，因此， 到2050年，65岁以上的AI/AN预计将增加两倍，而85岁以上的AI/AN数量将增加7倍。19 预计国家卫生机构的费用也将相应增加。因此，必须与迅速发展的 ADRD研究中的土著老年人人口。

RECRUITMENT AND ENGAGEMENT CORE: ABSTRACT Many American Indian, Alaska Native (AI/AN), and Native Hawaiian and Pacific Islander (NHPI) communities view academic research with skepticism, mistrust, or even hostility, in part because research has historically been done in or on communities rather than with community participation. As a result, community-informed participatory approaches have become the model of choice for research with AI/ANs and NHPIs, because their core values include equitable distribution of power and resources among partners and mutual respect for the knowledge that partners offer. In 2013, the National Institute on Aging convened a workshop to articulate goals for research on Alzheimer’s disease and related dementias as part of the National Plan to Address Alzheimer's Disease. A priority was the inclusion of disparity populations in research. However, AI/ANs and NHPIs have been largely neglected by this work, despite striking increases in life expectancy among Native elders. For example, the 32 current Alzheimer’s Disease Centers have recruited only 110 AI/ANs and 19 NHPIs in the last 7 years (average of 1 person every 2 years per center), despite existing recommendations to increase diversity. The Recruitment and Engagement Core will apply strategies recommended by the National Institutes on Aging for recruitment and retention in Alzheimer’s disease and related dementias (ADRD) research,17 with a commitment to innovative as well as traditional methods to engage communities. These strategies include a network of 8 Satellite Centers led by AI/AN and NHPI investigators representing a diverse cross-section of academic and community partners, which will extend the national impact of our work beyond our Research Projects. These Centers will assess research readiness and through novel “Brain Train” hands-on workshops, establish an IRB-approved registry of AI/ANs and NHPIs who wish to participate in ADRD research. Our Specific Aims are to: 1) Monitor and evaluate recruitment and retention in Research Projects by applying innovative strategies, and identifying best practices for ADRD outreach and engagement; 2) Assess community research readiness and position AI/AN and NHPI sites for future ADRD studies through a network of Satellite Centers and “Brain Train” ADRD workshops; 3) Build an IRB-approved research and information registry of AI/ANs and NHPIs interested in ADRD research; and 4) Create educational and recruitment materials to increase awareness of ADRD for use by the Research Projects in local communities and national venues. This Core will use strategies designed to stoke interest in research and treatment advances, both in communities participating in the Research Projects and in others and ensure stakeholder involvement in biospecimen collection and dissemination of results. The AI/AN population is growing 3 times faster than the US general population, such that the number of AI/ANs aged 65+ is expected to triple by 2050, while the number of those aged 85+ will increase 7-fold.19 Corresponding increases are expected for NHPIs. Thus it is imperative to engage the rapidly burgeoning population of Native elders in ADRD research.