Radionuclides in Food - Capability/Capacity Development

项目摘要-学科C：放射化学，轨道2 新泽西卫生部（NJDOH）公共卫生和环境实验室（PHEL） 美国食品和药物管理局（FDA）的实验室灵活资助模式合作 该协议的重点是提高新泽西州的能力和能力，以维护食品安全和保障。在这 根据该项目，放射分析实验室将通过以下方式扩大放射化学能力： a）购买一套新的16探测器比例计数系统（Tennessee LB 4200），以扩大 总阿尔法/贝塔测试。新仪器将主要用于分析食品中的总α/β 样品 B）雇用一名全职研究科学家和一名实验室技术员，以维持 分析食物。研究科学家将进行食品样品的放射化学制备， 和维护工具，并制定方法，以支持合作协定的目标。 c）开发牛奶中I-131的快速制备和分析方法， 用于核事故后恢复阶段牛奶中低水平I-131测量（< 1 pCi/L）。 的 实验室将开发一种方法，通过一批树脂将碘集中在树脂上- 阴离子交换技术碘-131将通过直接计数树脂的β来测定 目前的方法要么不够敏感，要么在时间和资源方面代价高昂。 Dowex-1×8离子交换 沉 背景液体闪烁计数器。样品制备可在4小时内完成。假设 样品在采集后4天内收到（衰减因子约为0.5），化学产率为80%，计数 效率为60%，计数30分钟，1.0 L样品的最低检出限将远低于1.0 pCi/L。从接收到报告的分析总时间可以在短短8小时内完成。 通过开展本提案中详述的工作和管理综合食品安全系统，NJDOH将 能够扩大其食品防御和安全活动，同时进一步保障公众健康。重要的是 由PHEL进行的工作将补充FDA和其他州的国家努力，同时提供我们的 联邦和州的合作伙伴，他们可以使用关键的放射性污染物数据来加强他们的食品防御 和安全活动。

Project Summary – Discipline C: Radiochemistry, Track 2 The New Jersey Department of Health (NJDOH) Public Health and Environmental Laboratories (PHEL) is pursuing the U.S. Food and Drug Administration (FDA)’s Laboratory Flexible Funding Model cooperative agreement focused on improving the capability and capacity of NJ to maintain food safety and security. In this project, the radioanalytical laboratory will expand the radiochemistry capability and capacity through: a) Purchasing a new 16-detectors proportional counting system (Tennelec LB4200) to expand the capacity of gross alpha/beta tests. The new instrument will primarily be used for the analysis of gross alpha/beta in food samples. b) Hiring a fulltime research scientist and a laboratory technician to maintain the personnel necessary for the analysis of food. The research scientist will perform radiochemical preparation of food samples, operation and maintenance of instruments, and methods development to support the cooperative agreement goals. c) Develop a rapid preparation and analysis method for I-131 in milk to provide surge capacity testing needed for low level I-131 measurement (< 1 pCi/L) for milk during the recovery phase following a nuclear event. The laboratory will develop a method to concentrate the iodine on a resin through a batch- anion-exchange technology. The Iodine-131 will be determined by directly counting beta of the resin Current methodologies are either not sensitive enough or are costly in terms of time and resources. Dowex-1×8 ion-exchange in a low background liquid scintillation counter. Sample preparation could be completed within four hours. Assuming the sample is received within four days of collection (decay factor ~0.5), 80% of chemical yield, and the counting efficiency of 60%, and counting of 30 minutes, the minimum detection limit for 1.0 L of sample will be far below 1.0 pCi/L. The total time of analysis from receival to report could be completed in as few as eight hours. By conducting the work detailed in this proposal and managing an integrated food safety system, NJDOH will be able to expand its food defense and safety activities while further safeguarding public health. Importantly, the work conducted by PHEL will supplement the national efforts of the FDA and other states while providing our federal and State partners with critical radiological contaminant data they can use to enhance their food defense and safety activities.