National Antimicrobial Resistance Monitoring System (NARMS) retail food surveillance in selected urban areas of northern California.

项目摘要 国家抗菌素耐药性监测系统(NARMS)是一项全国性的监测 监测肠道细菌对医学相关抗菌剂敏感性的系统 以帮助评估兽用抗菌剂的使用对人类健康的影响。NARMS 零售食品监测计划，食品和药品管理局的合作项目 兽医管理中心(FDA/CMV)、疾病预防控制中心以及州和地方卫生 各部门，通过改进抗菌剂的检测和监测来支持这项任务 生鲜零售肉制品中肠道细菌的耐药性。为了实现这一目标，我们 建议从随机抽样的零售店购买和测试生肉、家禽和海鲜 旧金山和加利福尼亚州圣何塞的市场。生肉将被送到Contra 科斯塔公共卫生实验室(CCPHL)，微生物学家将在那里尝试分离 来自所有肉类样本的沙门氏菌；仅来自家禽样本的弯曲杆菌；以及 海产品样品中的肠球菌、气单胞菌、弧菌和其他乳糖阳性细菌。全 分离株将被送往FDA/CMV进行抗生素耐药性测试。对于每种产品 购买时，我们会记录店铺名称和位置、品牌名称、保质期、购买 日期、包装类型和原产地(如果可用)。除了监控 生肉中细菌的流行率和抗菌素耐药性的趋势，这些数据是至关重要的 对食源性暴发疫情进行调查，并帮助提供有关使用抗菌剂的参数 兽医。这些数据将与相关合作伙伴共享，并可供公众使用 卫生专业人员促进干预措施，以减少食源性细菌的耐药性。

Project Summary The National Antimicrobial Resistance Monitoring System (NARMS) is a national surveillance system that monitors the susceptibility of enteric bacteria to medically relevant antimicrobials in order to help assess the impact of veterinary antimicrobial use on human health. The NARMS Retail Food Surveillance Program, a collaborative project between the Food and Drug Administration Center for Veterinary Medicine (FDA/CMV), the CDC, and state and local health departments, supports this mission by improving detection of and surveillance for antimicrobial resistance among enteric bacteria in raw retail meat commodities. To achieve this goal, we propose to purchase and test raw meat, poultry, and seafood from randomly sampled retail markets in San Francisco and San Jose, California. Raw meat will be delivered to the Contra Costa Public Health Laboratory (CCPHL) where microbiologists will attempt to isolate Salmonella from all meat samples; Campylobacter from poultry samples only; and Enterococcus, Aeromonas, Vibrio and other lactose positive bacteria from seafood samples. All isolates will be forwarded to FDA/CMV for antibiotic resistance testing. For each product purchased, we will record the store name and location, brand name, sell-by date, purchase date, packaging type, and the country of origin, when available. In addition to monitoring the prevalence of bacteria and trends in antimicrobial resistance in raw meat, these data are vital to foodborne outbreak investigations and help to inform parameters for antimicrobial use in veterinary medicine. These data will be shared with relevant partners and can be used by public health professionals to promote interventions to reduce resistance among foodborne bacteria.