Pennsylvania Retail Meat Program - Collaboration with FDA National Antimicrobial Resistance Monitoring Systems (NARMS)

宾夕法尼亚州耐药肠道细菌综合监测 摘要 动物源性食源性病原菌的耐药性，包括沙门氏菌和 弯曲杆菌引起了人们的极大关注。宾夕法尼亚州有动力继续参与 国家抗菌素监测系统(NARMS)对零售肉类的监测有两个原因。 首先，该计划使我们能够为FDA对抗生素的监管做出贡献， 直接让我们的居民受益。第二，该计划支持对 食源性疾病临床分离株与肠道细菌的比较 从肉类样本中找到的。这种对比有利于疫情的调查、追查 受污染产品，以及美国农业部食品安全局对屠宰场检查的优先顺序 和检查服务。我们研究战略的主要成果包括更好的协调 并与FDA交换数据和分离株，提高监测的及时性 系统。此外，我们已经并将继续努力提高数据质量和 记录的完整性。此外，NARMS监测结果的使用情况有所改善 就社区和农场中明智地使用抗生素进行沟通。我们的研究 将包括预先批准的试点研究，所有活动将在州公共卫生部门完成 和兽医实验室以及宾夕法尼亚州立农业学院的研究实验室 科学。

Pennsylvania Integrated Surveillance for Antimicrobial Resistance Enteric Bacteria Abstract Antimicrobial resistance in foodborne pathogens of animal origin, including Salmonella and Campylobacter, is of great concern. Pennsylvania is motivated to continue to participate in National Antimicrobial Monitoring System (NARMS) retail meat surveillance for two reasons. First, the program enables us to contribute to the FDA’s regulatory oversight for antibiotics, which directly benefits our residents. Second, this program supports integrated surveillance for enteric bacteria by comparing clinical isolates involved in foodborne illnesses with those recovered from meat samples. This comparison facilitates outbreaks investigation, trace-back of contaminated products, and prioritization of slaughterhouse inspections by USDA Food Safety and Inspection Service. Key outcomes from our research strategy include better coordination and exchange of data and isolates with the FDA and improved timeliness of the surveillance system. Additionally, our efforts have and will continue to improve data quality and completeness of records. Further, use of NARMS surveillance findings have improved communication about judicious antibiotic use in the community and on the farm. Our research will include pre-approved pilot studies and all activities will be completed in state public health and veterinary laboratories and in research laboratories at Penn State College of Agricultural Sciences.