Strengthen Antibiotic Resistance Surveillance in Retail Food Specimens in Kansas as a Part of the National Antimicrobial Resistance Monitoring System

项目摘要 加强我市零售食品中抗生素耐药性监测 堪萨斯州作为国家抗菌素耐药性监测系统的一部分 作为对抗细菌抗菌素耐药性(AMR)的关键活动， 国家抗生素耐药性监测系统(NARMS)自1996年以来监测 食源性致病菌的AMR和当时食用动物的指示细菌种 对其加工；在红肉、家禽中，自2020年以来还在海产品中销售到 零售业的普通公众；以及人类食源性感染。程序监控 零售食品AMR由食药监中心牵头管理--报载 兽医(FDA-CVM)。食品样品采集与微生物学 分析由各个州的项目站点执行。堪萨斯州的网站是 成立于2016年，现场团队已经完成了NARMS零售食品 收集和接受微生物监测的方案活动 堪萨斯州零售食品的分析样本。世界上最大的创新之一 最近几年的计划已经增加了全基因组测序和注释 从零售食品样本中获得的细菌分离物。这个新项目将使 堪萨斯州现场团队继续在堪萨斯州开展先前的方案活动， 增加了细菌分离株的常规全基因组测序和注释 从堪萨斯州零售店收集的食品样本中获得。细菌分离物， 他们的流行病学和基因组数据将与堪萨斯州卫生部共享 健康与环境。该部将使用这些监测数据和材料 促进该州的公共卫生，并为规划和政策发展提供信息。这个 结果还将用于教育和提高公众对AMR的认识。这个 分离物，它们的流行病学和基因组数据将被提供给NARMS 按要求的时间表实施零售食品监督计划。项目团队将使用 这些数据和材料用于加强AMR监测和食源性疫情 分析并推动国家层面的计划和政策发展。因此， 该项目将加强AMR监测和分析，支持食源性疫情 调查，告知抗菌药物管理，促进公共卫生 堪萨斯州和全国范围内。

Project Summary Strengthen Antibiotic Resistance Surveillance in Retail Food Specimens in Kansas as a Part of the National Antimicrobial Resistance Monitoring System As a key activity in combating bacterial antimicrobial resistance (AMR), the National Antimicrobial Resistance Monitoring System (NARMS) since 1996 monitors AMR in foodborne pathogens and indicator bacterial species in food-animals at the time of their processing; in red meat, poultry, and since 2020 also in seafood products sold to the general public in retail; and in human foodborne infections. The program monitoring AMR in retail food is led and managed by the Food and Drug Administration – Center for Veterinary Medicine (FDA-CVM). The food sample collection and microbiologic analysis are performed by the program sites in individual states. The site in Kansas was established in 2016, and the site-team has performed the NARMS Retail Food Surveillance programmatic activities of collecting and subjecting to microbiologic analysis samples of food retailed in Kansas. One of the major innovations in the program in recent years has been addition of whole genome sequencing and annotation of the bacterial isolates obtained from retail food samples. This new project will enable the Kansas site-team to continue the prior programmatic activities in Kansas, with the addition of a routine whole genome sequencing and annotation of bacterial isolates obtained from food samples collected in retail stores in Kansas. The bacterial isolates, and their epidemiologic and genomic data will be shared with the Kansas Department of Health and Environment. The Department will use these surveillance data and materials to advance public health in the state and inform program and policy development. The results will be also used to educate about and raise public awareness of AMR. The isolates, and their epidemiologic and genomic data will be delivered to the NARMS Retail Food Surveillance program on the required schedule. The program team will use these data and materials to enhance AMR surveillance and foodborne outbreak analysis, and enable program and policy development at the national level. Therefore, this project will strengthen AMR surveillance and analysis, support foodborne outbreak investigation, inform antimicrobial drug stewardship, and promote public health in Kansas and nation-wide.