Strengthen Antibiotic Resistance Surveillance in Retail Food Specimens in Kansas as a Part of the National Antimicrobial Resistance Monitoring System

项目摘要 加强香港零售食物样本的抗生素耐药性监测 堪萨斯作为国家抗菌素耐药性监测系统的一部分 作为对抗细菌抗菌素耐药性（AMR）的关键活动， 自1996年以来，国家抗菌素耐药性监测系统（NARMS）监测 当时食源性病原体和食用动物指示细菌的AMR 他们的加工;红肉，家禽，自2020年以来也在海鲜产品销售到 零售业中的公众;以及人类食源性感染。节目监测 零售食品中的AMR由食品和药物管理局-中心领导和管理 兽医学（FDA-CVM）食物样本收集及微生物化验 分析是由各个州的方案地点进行的。在堪萨斯的网站是 成立于2016年，该网站团队已经执行了NARMS零售食品 监测方案活动的收集和进行微生物 分析堪萨斯零售食品的样本。其中一个主要的创新， 近几年的计划增加了全基因组测序和注释 从零售食物样本中分离出来的细菌。这个新项目将使 堪萨斯现场团队继续之前在堪萨斯的计划活动， 增加细菌分离株的常规全基因组测序和注释 从堪萨斯零售店收集的食品样本中获得。分离出的细菌， 他们的流行病学和基因组数据将与堪萨斯卫生部共享。 健康和环境。本署会利用这些监察数据及资料， 促进该州的公共卫生，并为方案和政策制定提供信息。的 研究结果还将用于教育和提高公众对AMR的认识。的 分离株及其流行病学和基因组数据将提交给NARMS 按要求的时间表执行零售食品监督计划。节目组将使用 这些数据和材料，以加强AMR监测和食源性疫情 分析，并在国家一级制定方案和政策。因此，我们认为， 该项目将加强AMR监测和分析，支持食源性疫情 调查，告知抗菌药物管理，并促进公共卫生， 堪萨斯和全国。

Project Summary Strengthen Antibiotic Resistance Surveillance in Retail Food Specimens in Kansas as a Part of the National Antimicrobial Resistance Monitoring System As a key activity in combating bacterial antimicrobial resistance (AMR), the National Antimicrobial Resistance Monitoring System (NARMS) since 1996 monitors AMR in foodborne pathogens and indicator bacterial species in food-animals at the time of their processing; in red meat, poultry, and since 2020 also in seafood products sold to the general public in retail; and in human foodborne infections. The program monitoring AMR in retail food is led and managed by the Food and Drug Administration – Center for Veterinary Medicine (FDA-CVM). The food sample collection and microbiologic analysis are performed by the program sites in individual states. The site in Kansas was established in 2016, and the site-team has performed the NARMS Retail Food Surveillance programmatic activities of collecting and subjecting to microbiologic analysis samples of food retailed in Kansas. One of the major innovations in the program in recent years has been addition of whole genome sequencing and annotation of the bacterial isolates obtained from retail food samples. This new project will enable the Kansas site-team to continue the prior programmatic activities in Kansas, with the addition of a routine whole genome sequencing and annotation of bacterial isolates obtained from food samples collected in retail stores in Kansas. The bacterial isolates, and their epidemiologic and genomic data will be shared with the Kansas Department of Health and Environment. The Department will use these surveillance data and materials to advance public health in the state and inform program and policy development. The results will be also used to educate about and raise public awareness of AMR. The isolates, and their epidemiologic and genomic data will be delivered to the NARMS Retail Food Surveillance program on the required schedule. The program team will use these data and materials to enhance AMR surveillance and foodborne outbreak analysis, and enable program and policy development at the national level. Therefore, this project will strengthen AMR surveillance and analysis, support foodborne outbreak investigation, inform antimicrobial drug stewardship, and promote public health in Kansas and nation-wide.