Enhancement of California's Integrated Food Safety and Security System

建议应用：加强加州的综合食品安全和保障系统 加州公共卫生部(CDPH)食品和药物实验室分部(FDLB)是 在微生物学(A)、化学学科下为FOA#PAR-20-105提交以下提案 (B)及D组别特别计划。自2008年以来，FDLB一直是FDA的蕨类实验室。联邦储蓄银行拥有 在以下方面实现参考的合作协议方案的目标的能力和能力 其训练有素的员工的经验和专业知识、可用的设施、成熟的经过验证的设备、 并持续参与蕨类培训、监督、能力测试等合作 协议计划活动。食品和药物管理局是国家食品药品监管的主要检测实验室 注册了加州制造食品监管计划标准的机构。 1.化学领域的三个项目(PI：徐大东博士，dadong.Xu@cdph.ca.gov)： (1)学科B轨道1，食品防御(150个样本)：我们精通所有三种蕨类化学 方法(CHE.0006、CHE.0008和EAM 4.7)以及FDLB开发的执行任务的方法 2)学科B轨道2，人类食品 检测(500个样品)：我们有能力和能力进行人类食品产品检测 各种分析物，如天然毒素、有毒金属、海鲜毒素和一些杀虫剂。我们会的 能够增强我们对包括维生素和药物残留在内的其他分析物的检测能力；3) 学科D特别项目，轨道3，化学方法开发/验证：我们适用于 参与所有单一和多个实验室对海产品中组胺、砷形态的验证， 瓶装水和奶制品中兽药残留的电感耦合等离子体质谱分析。 2.微生物领域的八个项目(PI：David Kiang博士，David.Kiang@cdph.ca.gov)： 纪律A轨道(1)食品防御-我们有能力分析所有建议的食品和食品 通过故意手段生产与微生物污染有关的产品，并加强 国家BLS2和BSL3实验室的网络能力和准备情况；轨道(2)人类食品 检测-我们可以通过对微生物的分析来改进食品检测监督计划 食品和环境样品；(3)动物性食品检验--我们可以分析动物 加强食品微生物污染和动物性食品检测监测 国家计划；轨道(4)全基因组测序；轨道(5)微生物能力/能力 2020-21年发展；D学科特别项目，轨道(1)微生物学和 化学；跟踪(2)NFSDX和ORAPP集成；跟踪(3)方法开发/验证 微生物学-我们将参与两个多实验室验证。

Proposed Application: Enhancement of California’s Integrated Food Safety and Security System The Food and Drug Laboratory Branch (FDLB), California Department of Public Health (CDPH) is submitting the following proposal for FOA# PAR-20-105, under disciplines of Microbiology (A), Chemistry (B), and discipline D Special Projects. FDLB has been an FDA FERN laboratory since 2008. FDLB has the capability and capacity to fulfill the goals of the referenced cooperative agreement program in terms of the experience and expertise of its trained staff, available facilities, established validated equipment, and its on-going participation in FERN training, surveillance, proficiency testing, and other cooperative agreement programs activities. FDLB is the primary testing laboratory for State food and drug regulatory agency which enrolled in California’s Manufactured Food Regulatory Program Standards. 1. Three projects in Chemistry area (PI: Dr. Dadong Xu, Dadong.Xu@cdph.ca.gov): (1) Discipline B Track 1, Food Defense (150 samples): We are proficient in all three FERN chemistry methods (CHE.0006, CHE.0008, and EAM 4.7) as well as FDLB-developed methods to carry out the tasks for this track, with capacity of more than 150 samples; 2) Discipline B Track 2, Human Food Product Testing (500 samples): We have the capability and capacity to perform human food product testing for a variety of analytes, such as natural toxins, toxic metals, seafood toxins, and some pesticides. We will be able to enhance our testing capability in additional analytes including vitamins and drug residues; 3) Discipline D Special Projects, Track 3, Method Development / Validation in Chemistry: We apply to participate in all the single and multi-laboratory validations for histamine, arsenic speciation in seafood, bottled water analysis using ICP-MS, and veterinary drug residues in milk products. 2. Eight Projects in Microbiology area (PI: Dr. David Kiang, David.Kiang@cdph.ca.gov): Discipline A track (1) Food Defense- We have the capacity to analyze all the proposed food and food products related to microbiological contamination through intentional means and to enhance the network capacity and readiness of state BLS2+ and BSL3 laboratories; track (2) Human Food Product Testing- We can improve the food testing surveillance programs through microbiological analysis of food products and environmental samples; track (3) Animal Food Product Test- We can analyze animal food products for microbiological contaminants and improve the animal food testing surveillance program for the state; Track (4) Whole Genome Sequencing; track ( 5) Microbiology Capability/Capacity development 2020-21; Discipline D Special Projects, track (1) Sample collection for microbiology and Chemistry; track (2) NFSDX and ORAPP integration; track (3) Method Development/Validation for microbiology - We will participate in the two multi-lab validations.