Enhancement of California's Integrated Food Safety and Security System

拟议的应用：增强加州的综合食品安全和保障系统 加州公共卫生部（CDPH）食品和药物实验室分支（FDLB） 提交以下FOA# PAR-20-105的提案，根据微生物学（A），化学 (B)，以及纪律D特别计划。FDLB自2008年以来一直是FDA FERN实验室。FDLB拥有 能力和能力，以实现所引用的合作协议计划的目标， 其经过培训的工作人员的经验和专业知识、可用设施、已确认的设备， 及其正在参与的FERN培训，监督，能力测试和其他合作 协议方案活动。FDLB是国家食品药品监管的主要检测实验室 该机构注册了加州的制造食品监管计划标准。 1.化学领域的三个项目（PI：徐大东博士，Dadong. cdph.ca.gov）： (1)学科B轨道1，食物防御（150个样本）：我们精通所有三种蕨类植物化学 方法（CHE.0006、CHE.0008和EAM 4.7）以及FDLB开发的执行任务的方法 该轨道可容纳150多个样品; 2）学科B轨道2，人类食品 测试（500个样品）：我们有能力对人类食品进行测试， 各种分析物，如天然毒素、有毒金属、海鲜毒素和一些农药。我们将 能够增强我们对其他分析物的检测能力，包括维生素和药物残留; 3） 学科D特殊项目，轨道3，化学方法开发/验证：我们申请 参与所有单个和多个实验室对海产品中组胺、砷形态的验证， 使用ICP-MS进行瓶装水分析，以及乳制品中的兽药残留。 2.微生物学领域的八个项目（主要研究者：大卫江博士，大卫.江@ cdph.ca.gov）： 纪律A轨道（1）食品防御-我们有能力分析所有提出的食品和食品 通过有意的手段，加强与微生物污染有关的产品， 国家BLS 2+和BSL 3实验室的网络能力和准备情况;跟踪（2）人类食品 测试-我们可以通过微生物分析， 食品和环境样品;跟踪（3）动物食品产品测试-我们可以分析动物 食品微生物污染物和改善动物食品检测监测 国家计划;轨道（4）全基因组测序;轨道（5）微生物学能力/能力 发展2020-21;学科D特别项目，轨道（1）微生物学和 化学;跟踪（2）NFSDX和ORAPP集成;跟踪（3）方法开发/验证 微生物学-我们将参与两项多实验室确认。

Proposed Application: Enhancement of California’s Integrated Food Safety and Security System The Food and Drug Laboratory Branch (FDLB), California Department of Public Health (CDPH) is submitting the following proposal for FOA# PAR-20-105, under disciplines of Microbiology (A), Chemistry (B), and discipline D Special Projects. FDLB has been an FDA FERN laboratory since 2008. FDLB has the capability and capacity to fulfill the goals of the referenced cooperative agreement program in terms of the experience and expertise of its trained staff, available facilities, established validated equipment, and its on-going participation in FERN training, surveillance, proficiency testing, and other cooperative agreement programs activities. FDLB is the primary testing laboratory for State food and drug regulatory agency which enrolled in California’s Manufactured Food Regulatory Program Standards. 1. Three projects in Chemistry area (PI: Dr. Dadong Xu, Dadong.Xu@cdph.ca.gov): (1) Discipline B Track 1, Food Defense (150 samples): We are proficient in all three FERN chemistry methods (CHE.0006, CHE.0008, and EAM 4.7) as well as FDLB-developed methods to carry out the tasks for this track, with capacity of more than 150 samples; 2) Discipline B Track 2, Human Food Product Testing (500 samples): We have the capability and capacity to perform human food product testing for a variety of analytes, such as natural toxins, toxic metals, seafood toxins, and some pesticides. We will be able to enhance our testing capability in additional analytes including vitamins and drug residues; 3) Discipline D Special Projects, Track 3, Method Development / Validation in Chemistry: We apply to participate in all the single and multi-laboratory validations for histamine, arsenic speciation in seafood, bottled water analysis using ICP-MS, and veterinary drug residues in milk products. 2. Eight Projects in Microbiology area (PI: Dr. David Kiang, David.Kiang@cdph.ca.gov): Discipline A track (1) Food Defense- We have the capacity to analyze all the proposed food and food products related to microbiological contamination through intentional means and to enhance the network capacity and readiness of state BLS2+ and BSL3 laboratories; track (2) Human Food Product Testing- We can improve the food testing surveillance programs through microbiological analysis of food products and environmental samples; track (3) Animal Food Product Test- We can analyze animal food products for microbiological contaminants and improve the animal food testing surveillance program for the state; Track (4) Whole Genome Sequencing; track ( 5) Microbiology Capability/Capacity development 2020-21; Discipline D Special Projects, track (1) Sample collection for microbiology and Chemistry; track (2) NFSDX and ORAPP integration; track (3) Method Development/Validation for microbiology - We will participate in the two multi-lab validations.