Discipline A: Microbiology, Analytical Track 2: Human Food Product Testing

学科 A：微生物学，分析轨道 2：人类食品测试

• 批准号: 10176083
• 负责人: Nancy Hall
• 金额: $ 10万
• 依托单位: UNIVERSITY OF IOWA
• 依托单位国家: 美国
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-09-01 至 2025-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10176083
• 关键词: Discipline; Microbiology; Analytical; Track; Human

Project Summary/Abstract - Microbiology: Analytical Track #2 : Human Food Product Testing: The State Hygienic Laboratory’s (SHL) participation in this project contributes to the overall objective of the grant by contributing to a risk-based and prevention focused food safety system that both FDA and SHL’s State of Iowa partners (Iowa Department of Inspections and Appeals and the Iowa Department of Public Health) can utilize. In addition, test results generated can be used to remove adulterated food from commerce and aide regulatory inspection programs in conducting investigations. The specific aims of this project are as follows: • Participate in the large single commodity/hazard pair analysis by testing 200 fresh produce samples for multiple pathogens: Salmonella, Shiga-toxin Escherichia coli (STEC) and Cyclospora (only 40 of these samples tested for Cyclospora). • Test two other commodities of interest to both FDA and SHL that have contributed to outbreaks recently; 25 ready to eat cereal for Salmonella and 25 assorted precut melons for Salmonella, STEC, and Listeria species • Participate in FDA-requested exercises to support and maintain readiness. • Participate in national special security event exercises, as available. • Participate in testing associated with suspected or credible threats to the food supply where a microbiological agent is suspected, as requested by FDA. Successful completion of this project will help the FDA enhance its nationally integrated food safety system and will strengthen its efforts to detect, prevent, and minimize foodborne exposures and ultimately reduce foodborne illness. This project will also be beneficial to SHL to improve its capability and capacity for testing large volumes of produce for a variety of pathogens, teach additional staff members these methods (especially Cyclospora), continue to work various processes with Iowa Department of Inspection and Appeals on sample collection and chain of custody which is crucial during outbreaks. Any pathogens that are found will also be DNA fingerprinted by whole genome sequencing and this data utilized statewide by IDPH and nationally by FDA for rapid outbreak detection and source identification to reduce foodborne illness.

项目摘要/摘要 - 微生物学： 分析轨道2：人类食品测试： 州卫生实验室（SHL）参与该项目 通过为FDA和SHL的基于风险和预防的食品安全系统做出贡献 爱荷华州合作伙伴（爱荷华州检查与上诉部和爱荷华州公共部 健康）可以利用。此外，生成的测试结果可用于从商业中清除掺假食品 以及进行调查的助手监管检查计划。 该项目的具体目的如下： •通过测试200个新鲜农产品样品的大商品/危害对分析 多种病原体：沙门氏菌，shiga-toxin Escherichia coli（STEC）和环孢子虫（其中只有40个 测试了环孢子虫的样品）。 •最近对FDA和SHL进行了另外两种感兴趣的商品，这些商品最近导致了爆发； 25准备食用沙门氏菌和25种沙门氏菌，STEC和李斯特菌的precut瓜 物种 •参加FDA要求的练习，以支持和保持准备就绪。 •参加国家特殊安全活动练习。 •参与与粮食供应的可疑威胁或可靠威胁相关的测试 根据FDA的要求，怀疑微生物剂。 成功完成该项目将有助于FDA增强其全国综合食品安全系统 并将加强其检测，预防和最大程度地减少食源性暴露并最终减少的努力 食源性疾病。该项目也将对SHL提高其能力和测试能力有益 大量用于各种病原体的农产品，教其他工作人员这些方法（尤其是 Cyclospora），继续与爱荷华州检查部的各种流程进行样本上诉 在爆发期间至关重要的监护权和链条。任何发现的病原体也将是 由整个基因组测序和该数据全州在IDPH和全国范围内使用的DNA指纹，并由 FDA用于快速爆发检测和来源鉴定，以减少食源性疾病。