Discipline A: Microbiology, Analytical Track 2: Human Food Product Testing

学科 A：微生物学，分析轨道 2：人类食品测试

• 批准号: 10176083
• 负责人: Nancy Hall
• 金额: $ 10万
• 依托单位: UNIVERSITY OF IOWA
• 依托单位国家: 美国
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-09-01 至 2025-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10176083
• 关键词: Discipline; Microbiology; Analytical; Track; Human

Project Summary/Abstract - Microbiology: Analytical Track #2 : Human Food Product Testing: The State Hygienic Laboratory’s (SHL) participation in this project contributes to the overall objective of the grant by contributing to a risk-based and prevention focused food safety system that both FDA and SHL’s State of Iowa partners (Iowa Department of Inspections and Appeals and the Iowa Department of Public Health) can utilize. In addition, test results generated can be used to remove adulterated food from commerce and aide regulatory inspection programs in conducting investigations. The specific aims of this project are as follows: • Participate in the large single commodity/hazard pair analysis by testing 200 fresh produce samples for multiple pathogens: Salmonella, Shiga-toxin Escherichia coli (STEC) and Cyclospora (only 40 of these samples tested for Cyclospora). • Test two other commodities of interest to both FDA and SHL that have contributed to outbreaks recently; 25 ready to eat cereal for Salmonella and 25 assorted precut melons for Salmonella, STEC, and Listeria species • Participate in FDA-requested exercises to support and maintain readiness. • Participate in national special security event exercises, as available. • Participate in testing associated with suspected or credible threats to the food supply where a microbiological agent is suspected, as requested by FDA. Successful completion of this project will help the FDA enhance its nationally integrated food safety system and will strengthen its efforts to detect, prevent, and minimize foodborne exposures and ultimately reduce foodborne illness. This project will also be beneficial to SHL to improve its capability and capacity for testing large volumes of produce for a variety of pathogens, teach additional staff members these methods (especially Cyclospora), continue to work various processes with Iowa Department of Inspection and Appeals on sample collection and chain of custody which is crucial during outbreaks. Any pathogens that are found will also be DNA fingerprinted by whole genome sequencing and this data utilized statewide by IDPH and nationally by FDA for rapid outbreak detection and source identification to reduce foodborne illness.

项目摘要/摘要-微生物学： 分析轨道2：人类食品产品检测： 国家卫生实验室(SHL)参与该项目有助于实现国家卫生实验室的总体目标 通过为FDA和SHL的基于风险和预防的食品安全体系做出贡献 爱荷华州合作伙伴(爱荷华州检查和申诉部和爱荷华州公共事务部 健康)可以利用。此外，所产生的检测结果可用于将掺假食品从商业中移除 并协助监管检查项目进行调查。 该项目的具体目标如下： ·通过测试200个新鲜农产品样本，参与大型单一商品/危险对分析 多种病原体：沙门氏菌、志贺毒素大肠杆菌(STEC)和环孢子菌(其中只有40种 检测环孢子菌的样本)。 ·测试另外两种FDA和SHL都感兴趣的商品，它们最近导致了疫情的爆发； 为沙门氏菌准备了25份谷类食品，为沙门氏菌、STEC和李斯特氏菌准备了25个各种预切好的甜瓜 物种 ·参加FDA要求的演习，以支持和保持准备状态。 ·如有可能，参加国家特别安全活动演习。 ·参与与怀疑或可信的粮食供应威胁有关的检测， 按照FDA的要求，怀疑是微生物制剂。 该项目的成功完成将有助于FDA加强其国家综合食品安全体系 并将加强努力，检测、预防和最大限度地减少食源性暴露，并最终减少 食源性疾病。该项目也将有利于SHL提高其测试能力和能力 大量生产各种病原体，向更多的工作人员传授这些方法(特别是 环孢子菌)，继续与爱荷华州检查和上诉部门就样品进行各种程序合作 收集和监管链，这在疫情期间是至关重要的。任何被发现的病原体也将是 通过全基因组测序确定DNA指纹，IDPH在全州范围内和全国范围内利用这些数据 FDA用于快速暴发检测和源头识别，以减少食源性疾病。