P20 Exploratory Center for Precision Health in Diverse Populations

项目总结 P20精准卫生探索中心在不同人群中的充实计划重点 代谢综合征(METS)及其引发的多种慢性病护理人才培养 (MCC)。充实计划旨在将早期职业护士科学家培养成成功的、 由NIH资助的独立调查人员。充实计划的首要目标是支持护士 科学家正在学习如何(1)理解和评估潜在的生物学和病理生理学 甲硫氨酸及其产生的MCC导致不同的症状和生物标记物的表达。(2)分析 种族、民族、年龄和性别与生物、行为和环境因素的关系 结果MCC，以及这些因素如何影响有效地进行护理研究所需的方法 不同的人群。(3)将METS及其产生的MCC工作台研究(T1/T2)带到床边(T3)和 将其融入日常临床实践(T4)。(四)发展有效高效的跨学科协同 团队将在大都会及其产生的MCC中开展研究。(五)理解和有效利用核心数据 在METS及其产生的MCC中设计和实施研究研究的要素。(6)评估 在大都会艺术博物馆上进行科学研究的伦理、法律和社会影响及其在不同领域产生的MCC 人口，包括使用生物标记物。该中心将通过利用广泛的 纽约大学罗里·迈耶斯护理学院(NYU Meyers)和纽约大学科学学院提供的资源 社区以及开发新的项目。纽约大学迈耶斯分校现有资源包括内部拨款 评论，演讲者系列，NIDA资助的P30药物使用和艾滋病毒研究中心，哈特福德研究所 老年护理，以及由NSF资助的X-LAB，它为医疗保健带来技术解决方案。新计划 专门为提供个人、小组和同伴指导而开发的。这些领域的计划将包括 《科学进展》月度研讨会，一个期刊俱乐部，以及一个写作责任和同行指导小组。 我们还将在博士后奖学金和访问学者项目中扩大导师和能力 大都会及其产生的MCC的区域。浓缩计划将制定和实施有针对性的 研讨会和为期一天的方法和科学方案，旨在通过以下方式确定需要的领域 年度需求评估。浓缩方案的活动将是高度可持续的，因为它们将是 编织到纽约大学迈耶斯的结构中，并适应现有的资源、结构和资金流。由 在五年P20期结束时，新课程将由教员自行维持，并由 纽约大学梅耶斯分校院长。浓缩计划将由一名经验丰富的外部科学家进行评估，他将 根据过程和结果的测量结果进行年度评审。评估将由以下人员进行审查 浓缩计划主任和行政核心，以确保计划最大化 在不同人群中发展早期护士科学家对蛋氨酸及其导致的MCC的研究。

PROJECT SUMMARY The Enrichment Program of the P20 Exploratory Center for Precision Health in Diverse Populations focuses on developing nurse scientists in Metabolic Syndrome (MetS) and its resulting multiple chronic conditions (MCC). The Enrichment Program seeks to foster the development early career nurse scientists into successful, NIH-funded, independent investigators. The overarching aims of the Enrichment Program are to support nurse scientists in learning how to (1) Understand and evaluate how the underlying biology and pathophysiology of MetS and its resulting MCC leads to differential symptom and biomarker expression. (2) Analyze the impact of race, ethnicity, age, and sex on biological, behavioral, and environmental factors leading to MetS and its resulting MCC, and how these factors influence the methods needed to effectively perform nursing research in diverse populations. (3) Take MetS and its resulting MCC bench research (T1/T2) to the bedside (T3) and integrate it into everyday clinical practice (T4). (4) Develop effective and efficient collaborative interdisciplinary teams to carry out research in MetS and its resulting MCC. (5) Understand and effectively use core data elements in the design and implementation of research studies in MetS and its resulting MCC. (6) Evaluate the ethical, legal and social implications of performing science on MetS and its resulting MCC in diverse populations, including the use of biomarkers. The center will achieve these aims by leveraging the extensive resources available at the NYU Rory Meyers College of Nursing (NYU Meyers) and the greater NYU scientific community as well as by developing new programs. Existing resources at NYU Meyers include internal grant reviews, speaker series, the NIDA-funded P30 Center in Drug Use and HIV Research, the Hartford Institute for Geriatric Nursing, and the NSF-funded X-lab, which brings technology solutions to healthcare. New programs developed specifically to provide individual, group, and peer mentoring. Programs in these areas will include a Science in Progress monthly seminar, a journal club, and a writing accountability and peer mentoring group. We will also expand mentorship and capacity in our post-doctoral fellowships and visiting scholar programs in the area of MetS and its resulting MCC. The Enrichment Program will develop and implement targeted seminars and day-long methodologic and scientific programs, targeted to areas of need as identified through an annual needs assessment. The Enrichment Program activities will be highly sustainable, as they will be woven into the fabric of NYU Meyers and fit into existing resources, structures, and funding streams. By the end of the five year P20 period, the new programs will be self-sustained by the faculty and by support from the Dean of NYU Meyers. The Enrichment Program will be evaluated by an experienced external scientist, who will perform an annual review based on process and outcome measurements. The evaluation will be reviewed by the Enrichment Program Director and the Administrative Core to ensure that the program maximizes the development of early-career nurse scientists in research on MetS and its resulting MCC in diverse populations.