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Transitions Clinic Network: Post Incarceration Addiction Treatment, Healthcare, and Social Support (TCN PATHS) study

Transitions Clinic Network：监禁后成瘾治疗、医疗保健和社会支持 (TCN PATHS) 研究

基本信息

批准号：
10177211
负责人：
Emily Ai-hua Wang
金额：
$ 39.82万
依托单位：
YALE UNIVERSITY
依托单位国家：
美国
项目类别：
财政年份：
2019
资助国家：
美国
起止时间：
2019-07-15 至 2024-04-30
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/10177211
关键词：
Address Affect Alcohol or Other Drugs use Biological California Cause of Death Centers for Disease Control and Prevention (U.S.)Clinic Clinical Research Clinical Trials County Criminal Justice Data Development Devices Discrimination Disease Environment Environmental Risk Factor Face Funding Future Goals Grant Health Healthcare Imprisonment Individual Infrastructure Intervention Jail Justice Knowledge Lead Light Link Maps Measures Mediating Mediator of activation protein Mission Morbidity - disease rate National Institute of Drug Abuse Neighborhoods Neurocognitive Nightmare Noise Overdose Pain Participant Patient Recruitments Pharmaceutical Preparations Pharmacology Post-Traumatic Stress Disorders Prevalence Public Health Relapse Research Role Sampling San Francisco Schedule Site Sleep Sleep Apnea Syndromes Sleep Deprivation Sleep disturbances Sleeplessness Social Network Social support Stress Surveys System Testing Time Transportation Transportation Noise Trauma Treatment outcome United States National Institutes of Health Wrist actigraphy addiction base depressive symptoms experience food insecurity high risk population housing instability illicit opioid improved indexing innovation medical schools negative affect novel opioid mortality opioid overdose opioid use opioid use disorder parent grant parent project patient oriented prescription opioid recidivism recruit sleep behavior sleep health sleep quality social stigma

项目摘要

PROJECT SUMMARY Sleep deficiency, which includes sleep deprivation, sleeping at the wrong time of day, or poor quality of sleep, may affect OUD treatment engagement and retention among people recently released from jail. Sleep deficiency may lead to biologic, psychiatric, and pharmacologic mechanisms, such as stress, negative affect, pain or other substance use that may increase the likelihood of illicit opioid use, and disengagement in OUD treatment. Further, release from incarceration may increase sleep deficiency. Incarcerated people are more likely to witness and directly experience trauma which can, in turn, affect sleep health by causing nightmares, insomnia, sleep apnea, and general sleep disruption. Release from incarceration can cause significant disruptions in sleep habits. In jails, people are often subjected to sleeping in environments where lights, noise, and schedule are out of their control or where they are medicated to sleep. Changes from that environment may create difficulties with sleep. Our long-term goal is to reduce morbidity and mortality from OUD among justice-involved individuals. The overall research objective of this supplement is to examine the association between sleep deficiency and OUD treatment retention in a sample of people receiving medications for OUD (MOUD) who were recently released from jail. This proposal brings together the expertise of two HEAL-funded grants at Yale School of Medicine, [5UG1DA050072-02-JCOIN, Transitions Clinic Network: Post Incarceration Addiction Treatment, Healthcare, and Social Support (TCN PATHS) and 1U01HL150596-01- The CLOUDS Study], both aimed at understanding and improving MOUD engagement and retention. The central hypothesis of this supplement is that sleep deficiency is associated with worse OUD treatment retention and that sleep environment is a novel mediator of this association. The underlying rationale for this study is that sleep deficiency must be addressed in a holistic manner to support OUD treatment engagement. We aim to: (1) Determine the prevalence of sleep deficiency and describe the sleep environment of a sample of people on MOUD recently released from jail; (2) Estimate the association between sleep deficiency and OUD treatment retention; and (3) Examine sleep environment as a potential mediator of sleep deficiency and OUD treatment retention in people recently released from jail. To achieve these aims, participants from two TCN PATHS sites (n=220) will complete the Pittsburg Sleep Quality Index (PSQI) and wear a device on their wrist (Actiwatch) that will record data on the participant’s sleep environment and ambient light during sleep. Additionally, we will use neighborhood-level noise and light data from the National Transportation Noise Map and the Centers for Disease Control and Prevention to describe participants’ sleep environment. We will measure OUD treatment retention at 1,3, and 6-months post release. This study will provide data for the future development and testing of patient-centered interventions focusing on sleep deficiency among OUD treatment participants that enhance their retention in treatment.

项目总结