Center Core Grant for Vision Research

项目摘要-整体中心核心 视力研究中心核心助学金的首要目标是支持、加强和扩大 南加州大学的基础和翻译视觉科学研究。中心核心将 为23名优秀调查人员提供共享资源，致力于澄清 眼科疾病的发病机制、诊断和治疗。目前，这些参与调查的人员持有 共有28项NIH资助的研究资助，其中包括来自NEI的20项研究资助(包括13项符合R01条件的研究资助 补助金)。中心核心将支持3个高度集成的资源核心：眼科治疗 工程核心，动物模型和活体成像核心，以及细胞和组织成像核心。这些核心 将提供卓越的设施、仪器设备和专业知识，这些都是增强和 扩大参与调查人员的研究项目，帮助现有调查人员进行研究 在新兴领域，并协助新的研究人员开发视觉研究项目。中心核心 还将协调和整合核心活动，促进创新新兴技术的利用，以及 促进跨学科的协作视野研究。中心核心将成为 开展有影响力的基础和转化性视觉研究，重点是提高生物学知识 和视觉系统的病理生理学以及新的视觉治疗方法的发展 减损。

Project Summary – Overall Center Core The overarching goal of the Center Core Grant for Vision Research is to support, strengthen and broaden basic and translational vision science research at the University of Southern California. The Center Core will provide shared resources accessible to a group of 23 outstanding investigators, dedicated to elucidating mechanisms, diagnosis, and treatment of ocular diseases. Currently, these participating investigators hold a total of 28 NIH-funded research grants, consisting of 20 research grants from NEI (including, 13 qualifying R01 grants). The Center Core will support 3 highly integrated Resource Cores: Ophthalmic Therapeutics Engineering Core, Animal Models and In Vivo Imaging Core, and Cell and Tissue Imaging Core. These Cores will offer exceptional facilities, instrumentation and expertise that are essential resources to enhance and expand the research programs of participating investigators, aid established investigators in pursuing research in new emerging fields, and assist new investigators in developing vision research projects. The Center Core will also coordinate and integrate Core activities, promote utilization of innovative emerging technologies, and facilitate collaborative inter-disciplinary vision research. The Center Core will serve as a cornerstone for conduct of impactful basic and translational vision research focused on advancing knowledge of the biology and pathophysiology of the visual system and development of novel therapeutic approaches for vision impairment.