Center Core Grant for Vision Research

项目概要-整体中心核心 视觉研究中心核心补助金的总体目标是支持，加强和扩大 在南加州大学从事基础和转化视觉科学研究。中心核心将 向23名杰出调查员提供共享资源， 眼科疾病的机制、诊断和治疗。目前，这些参与调查的研究人员持有一份 总共有28项NIH资助的研究赠款，包括NEI的20项研究赠款（包括13项合格的R 01 赠款）。中心核心将支持3个高度集成的资源核心：眼科治疗 工程核心，动物模型和体内成像核心，细胞和组织成像核心。这些核 将提供特殊的设施，仪器和专业知识，这些都是提高和 扩大参与研究者的研究计划，帮助已建立的研究者进行研究 在新兴领域，并协助新的研究人员在发展视觉研究项目。中心磁芯 还将协调和整合核心活动，促进创新新兴技术的利用， 促进跨学科视觉研究的合作。中心核心将作为基石， 开展有影响力的基础和转化视觉研究，重点是推进生物学知识 和视觉系统的病理生理学和发展新的治疗方法的视觉 损伤

Project Summary – Overall Center Core The overarching goal of the Center Core Grant for Vision Research is to support, strengthen and broaden basic and translational vision science research at the University of Southern California. The Center Core will provide shared resources accessible to a group of 23 outstanding investigators, dedicated to elucidating mechanisms, diagnosis, and treatment of ocular diseases. Currently, these participating investigators hold a total of 28 NIH-funded research grants, consisting of 20 research grants from NEI (including, 13 qualifying R01 grants). The Center Core will support 3 highly integrated Resource Cores: Ophthalmic Therapeutics Engineering Core, Animal Models and In Vivo Imaging Core, and Cell and Tissue Imaging Core. These Cores will offer exceptional facilities, instrumentation and expertise that are essential resources to enhance and expand the research programs of participating investigators, aid established investigators in pursuing research in new emerging fields, and assist new investigators in developing vision research projects. The Center Core will also coordinate and integrate Core activities, promote utilization of innovative emerging technologies, and facilitate collaborative inter-disciplinary vision research. The Center Core will serve as a cornerstone for conduct of impactful basic and translational vision research focused on advancing knowledge of the biology and pathophysiology of the visual system and development of novel therapeutic approaches for vision impairment.