Center Core Grant for Vision Research

项目总结：总体中心核心 视觉研究中心核心补助金的总体目标是支持，加强和扩大 在南加州大学从事基础和转化视觉科学研究。中心核心将 向28名杰出调查员提供共享资源， 眼部疾病的机制、诊断和治疗。目前，这些参与调查的研究人员 累计持有28项NIH资助的研究赠款，其中21赠款NEI（13项R 01，1项R21，7项K- 其他研究所的7笔赠款（4笔R 01，1笔R21，1笔RF 1，1笔K 08）。中心核心将支持3 高度集成的资源核心：1）眼科治疗工程核心，2）细胞和组织成像 和数据科学核心，3）动物模型和体内成像核心。这些核心将提供卓越的 设施、仪器和专业知识是加强和扩大研究的必要资源 参与研究者的计划，帮助既定的研究者在新兴领域进行研究， 领域，并协助新的研究人员开发视觉研究项目。中心核心还将 协调和整合核心活动，促进创新新兴技术的利用， 跨学科的视觉研究。中心核心将作为开展以下活动的基石： 有影响力的基础和转化视觉研究，重点是推进生物学知识， 视觉系统的病理生理学和新的诊断和治疗方法的发展， 视力障碍

PROJECT SUMMARY: OVERALL CENTER CORE The overarching goal of the Center Core Grant for Vision Research is to support, strengthen and broaden basic and translational vision science research at the University of Southern California. The Center Core will provide shared resources accessible to a group of 28 outstanding investigators, dedicated to elucidating mechanisms, diagnosis, and treatment of ocular diseases. Currently, these participating investigators cumulatively hold 28 NIH-funded research grants, consisting of 21 grants from NEI (13 R01s, 1 R21, 7 K- awards) and 7 grants from other institutes (4 R01s, 1 R21, 1 RF1, 1 K08). The Center Core will support 3 highly integrated Resource Cores: 1) Ophthalmic Therapeutics Engineering Core, 2) Cell & Tissue Imaging and Data Science Core, 3) Animal Models and In Vivo Imaging Core. These Cores will offer exceptional facilities, instrumentation and expertise that are essential resources to enhance and expand the research programs of participating investigators, aid established investigators in pursuing research in new emerging fields, and assist new investigators in developing vision research projects. The Center Core will also coordinate and integrate Core activities, promote utilization of innovative emerging technologies, and facilitate collaborative inter-disciplinary vision research. The Center Core will serve as a cornerstone for conduct of impactful basic and translational vision research focused on advancing knowledge of the biology and pathophysiology of the visual system and development of novel diagnostic and therapeutic approaches for vision impairment.