Center Core Grant for Vision Research
视觉研究中心核心资助
基本信息
- 批准号:10714512
- 负责人:
- 金额:$ 65.23万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2018
- 资助国家:美国
- 起止时间:2018-09-30 至 2028-06-30
- 项目状态:未结题
- 来源:
- 关键词:Animal ModelBiologyCaliforniaCenter Core GrantsData Science CoreDedicationsDiagnosisEmerging TechnologiesEngineeringEnsureEnvironmentEye diseasesFosteringFunctional disorderFundingGoalsGrantInterdisciplinary StudyK-Series Research Career ProgramsKnowledgeMentorsProductivityResearchResearch PersonnelResearch Project GrantsResource SharingResourcesTechnical ExpertiseTherapeuticTissue imagingUnited States National Institutes of HealthUniversitiesVision researchVisual SystemVisual impairmentcellular imagingcollaborative environmentexperienceimaging sciencein vivo imaginginnovationinnovative technologiesinstrumentationnovel diagnosticsnovel therapeutic interventionprogramssuccessvision developmentvision science
项目摘要
PROJECT SUMMARY: OVERALL CENTER CORE
The overarching goal of the Center Core Grant for Vision Research is to support, strengthen and broaden
basic and translational vision science research at the University of Southern California. The Center Core will
provide shared resources accessible to a group of 28 outstanding investigators, dedicated to elucidating
mechanisms, diagnosis, and treatment of ocular diseases. Currently, these participating investigators
cumulatively hold 28 NIH-funded research grants, consisting of 21 grants from NEI (13 R01s, 1 R21, 7 K-
awards) and 7 grants from other institutes (4 R01s, 1 R21, 1 RF1, 1 K08). The Center Core will support 3
highly integrated Resource Cores: 1) Ophthalmic Therapeutics Engineering Core, 2) Cell & Tissue Imaging
and Data Science Core, 3) Animal Models and In Vivo Imaging Core. These Cores will offer exceptional
facilities, instrumentation and expertise that are essential resources to enhance and expand the research
programs of participating investigators, aid established investigators in pursuing research in new emerging
fields, and assist new investigators in developing vision research projects. The Center Core will also
coordinate and integrate Core activities, promote utilization of innovative emerging technologies, and facilitate
collaborative inter-disciplinary vision research. The Center Core will serve as a cornerstone for conduct of
impactful basic and translational vision research focused on advancing knowledge of the biology and
pathophysiology of the visual system and development of novel diagnostic and therapeutic approaches for
vision impairment.
项目总结:总体中心核心
视觉研究中心核心补助金的总体目标是支持,加强和扩大
在南加州大学从事基础和转化视觉科学研究。中心核心将
为28名杰出调查人员提供共享资源,致力于阐明
眼科疾病的机制、诊断和治疗。目前,这些参与调查的研究人员
累计持有28项NIH资助的研究赠款,其中21赠款NEI(13项R 01,1项R21,7项K-
其他研究所的7笔赠款(4笔R 01,1笔R21,1笔RF 1,1笔K 08)。中心核心将支持3
高度集成的资源核心:1)眼科治疗工程核心,2)细胞和组织成像
和数据科学核心,3)动物模型和体内成像核心。这些核心将提供卓越的
设施、仪器和专业知识是加强和扩大研究的必要资源
参与研究者的计划,帮助既定的研究者在新兴领域进行研究,
领域,并协助新的研究人员开发视觉研究项目。中心核心还将
协调和整合核心活动,促进创新新兴技术的利用,
跨学科的视觉研究。中心核心将作为开展以下活动的基石:
有影响力的基础和转化视觉研究,重点是推进生物学知识,
视觉系统的病理生理学和新的诊断和治疗方法的发展,
视力障碍
项目成果
期刊论文数量(27)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
Perioperative Considerations for Antithrombotic Therapy in Oculofacial Surgery: A Review of Current Evidence and Practice Guidelines.
- DOI:10.1097/iop.0000000000002058
- 发表时间:2022-05-01
- 期刊:
- 影响因子:2
- 作者:Kim, Christian;Pfeiffer, Margaret L.;Chang, Jessica R.;Burnstine, Michael A.
- 通讯作者:Burnstine, Michael A.
Argus II Retinal Prosthesis Implantation in a Patient With a History Of Strabismus Surgery:A Surgical Technique.
对有斜视手术史的患者进行 Argus II 视网膜假体植入:一种手术技术。
- DOI:10.3928/23258160-20190129-09
- 发表时间:2019
- 期刊:
- 影响因子:0
- 作者:Narala,Ramsudha;Humayun,MarkS;Ameri,Hossein
- 通讯作者:Ameri,Hossein
Matrix metalloproteinase-9 (MMP-9) and tissue inhibitor of metalloproteinases 1 (TIMP-1) are localized in the nucleus of retinal Müller glial cells and modulated by cytokines and oxidative stress.
- DOI:10.1371/journal.pone.0253915
- 发表时间:2021
- 期刊:
- 影响因子:3.7
- 作者:Lee EJ;Zheng M;Craft CM;Jeong S
- 通讯作者:Jeong S
Elimination of a False-Negative Result With the M-CHARTS Metamorphopsia Assessment Tool Achieved Through Sampling Oblique Axes.
通过斜轴采样实现 M-CHARTS 视觉变形评估工具消除假阴性结果。
- DOI:10.3928/23258160-20191031-09
- 发表时间:2019
- 期刊:
- 影响因子:0
- 作者:Lifton,JacobA;Moshfeghi,AndrewA
- 通讯作者:Moshfeghi,AndrewA
Alterations in Retinal Vascular and Oxygen Metrics in Treated and Untreated Proliferative Diabetic Retinopathy: A Case Report.
- DOI:10.1159/000526569
- 发表时间:2022-09
- 期刊:
- 影响因子:0.4
- 作者:Rahimi, Mansour;Kashani, Amir H.;Blair, Norman P.;Shahidi, Mahnaz
- 通讯作者:Shahidi, Mahnaz
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{{ truncateString('Mahnaz Shahidi', 18)}}的其他基金
Imaging of Retinal Oxygen Metabolism in Diabetic Retinopathy
糖尿病视网膜病变的视网膜氧代谢成像
- 批准号:
9886053 - 财政年份:2020
- 资助金额:
$ 65.23万 - 项目类别:
Imaging of Retinal Oxygen Metabolism in Diabetic Retinopathy
糖尿病视网膜病变视网膜氧代谢的成像
- 批准号:
10549308 - 财政年份:2020
- 资助金额:
$ 65.23万 - 项目类别:
Imaging of Retinal Oxygen Metabolism in Diabetic Retinopathy
糖尿病视网膜病变视网膜氧代谢的成像
- 批准号:
10320926 - 财政年份:2020
- 资助金额:
$ 65.23万 - 项目类别:
Imaging of Retinal Oxygen Metabolism in Diabetic Retinopathy
糖尿病视网膜病变视网膜氧代谢的成像
- 批准号:
10077556 - 财政年份:2020
- 资助金额:
$ 65.23万 - 项目类别:
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