Translational Aging Research Training Program

转化衰老研究培训计划

• 批准号: 10179264
• 负责人: Jeremy D Walston
• 金额: $ 57.09万
• 依托单位: JOHNS HOPKINS UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2018
• 资助国家: 美国
• 起止时间: 2018-05-01 至 2023-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10179264
• 关键词: Aging; Research Training; Training Programs

The population of older adults with chronic disease states and functional and cognitive decline is growing rapidly in the US and around the world. In parallel, there has been a rapid expansion in the understanding of aging-related biological changes that may impact these conditions. Despite these parallel trends, there has to date been minimal application of this new biological knowledge to the health and well-being of older adults. A critical mass of interdisciplinary aging research expertise and infrastructure has evolved at Johns Hopkins University that has greatly accelerated the translational capability of faculty members and trainees. However, a notable gap in salary support for post-doctoral fellows interested in translational aging research has slowed the development of a robustly trained scientific workforce in this critical area of investigation. The Translational Aging Research Training Program described here will help fill a crucial gap in the training. This development of expertise will take place through a series of classroom and experiential learning opportunities leveraged from the outstanding aging-focused research and training programs that already exist at Johns Hopkins University. The scientific leadership, the infrastructure, the collaborative nature, and the collegial environment provided by these programs and affiliated faculty will enable the provision of broad exposure to all trainees to the tenets of basic aging biology as well as to the major tenets of clinical investigation and clinical teaching relevant to older adults across a number of health care disciplines. Specific aims include: 1) the implementation of a rigorous interdisciplinary training program in translational aging research for post-doctoral fellows with MD and PhD degrees through a structured program consisting of a core series of required coursework and interdisciplinary scientific meetings, weekly trainee focused translational aging seminars offered by aging-focused research programs across the Johns Hopkins Medical Institutions, the development of an individualized training program, and a series of leadership and career development seminars that will help to ensure future leadership in this important area of investigation; 2) the provision of trainees with a primary directed translational aging laboratory or clinically oriented research project in collaboration with an experienced mentor with research resources; 3) the provision of trainees with access to the robust interdisciplinary and translation-focused aging research infrastructure and collaborative research opportunities available across the Johns Hopkins Medical Institutions. At the end of this training program, trainees will have a broad interdisciplinary knowledge of basic aging biology and major clinical issues facing older adults, a broad knowledge of translational science, and specific research skills will enable successful future academic careers. Further, the trainee will have learned career development and leadership skill sets that will facilitate the future development of influential interdisciplinary translational aging careers and research programs.

患有慢性疾病以及功能和认知能力下降的老年人人数正在增加 在美国和世界各地迅速。与此同时，对以下问题的认识也迅速扩大： 与衰老相关的生物学变化可能会影响这些条件。尽管有这些平行的趋势， 迄今为止，这一新的生物学知识在老年人的健康和福祉方面的应用很少。一 在约翰霍普金斯，跨学科的老龄化研究专业知识和基础设施的临界质量已经发展起来 这所大学大大提高了教师和学员的翻译能力。然而，在这方面， 对转译老龄化研究感兴趣的博士后研究员的工资支持的显著差距已经减缓 在这一关键的调查领域发展一支训练有素的科学队伍。平移 这里描述的老龄化研究培训计划将有助于填补培训中的一个关键空白。这一发展 将通过一系列课堂和体验式学习机会， 从约翰霍普金斯大学已经存在的杰出的以衰老为重点的研究和培训项目中 大学科学领导、基础设施、协作性质和学院环境 由这些计划和附属教师提供的将使所有学员能够广泛接触， 基本衰老生物学的原则以及临床研究和临床教学的主要原则 与许多医疗保健学科的老年人相关。具体目标包括：（1） 实施严格的跨学科培训计划，在转化老龄化研究的博士后 研究员与MD和博士学位通过结构化的程序组成的核心系列所需的 课程和跨学科的科学会议，每周学员集中翻译老化研讨会 由约翰霍普金斯医疗机构的以衰老为重点的研究项目提供， 个性化的培训计划，以及一系列的领导力和职业发展研讨会， 有助于确保未来在这一重要调查领域的领导地位; 2）为学员提供 主要指导翻译老化实验室或临床导向的研究项目与合作， 经验丰富的导师与研究资源; 3）为学员提供获得强大的 跨学科和以预防为重点的老龄化研究基础设施和合作研究机会 在约翰霍普金斯医疗机构都可以买到。培训结束后，学员将 基础衰老生物学和老年人面临的主要临床问题的广泛的跨学科知识，广泛的 翻译科学的知识和具体的研究技能将使成功的未来学术生涯。 此外，受训者还将学习职业发展和领导技能，这将有助于未来的发展。 发展有影响力的跨学科翻译老龄化事业和研究计划。