Translational Aging Research Training Program

转化衰老研究培训计划

• 批准号: 10436961
• 负责人: Jeremy D Walston
• 金额: $ 21.64万
• 依托单位: JOHNS HOPKINS UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2018
• 资助国家: 美国
• 起止时间: 2018-05-01 至 2024-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10436961
• 关键词: Aging; Research Training; Training Programs

The population of older adults with chronic disease states and functional and cognitive decline is growing rapidly in the US and around the world. In parallel, there has been a rapid expansion in the understanding of aging-related biological changes that may impact these conditions. Despite these parallel trends, there has to date been minimal application of this new biological knowledge to the health and well-being of older adults. A critical mass of interdisciplinary aging research expertise and infrastructure has evolved at Johns Hopkins University that has greatly accelerated the translational capability of faculty members and trainees. However, a notable gap in salary support for post-doctoral fellows interested in translational aging research has slowed the development of a robustly trained scientific workforce in this critical area of investigation. The Translational Aging Research Training Program described here will help fill a crucial gap in the training. This development of expertise will take place through a series of classroom and experiential learning opportunities leveraged from the outstanding aging-focused research and training programs that already exist at Johns Hopkins University. The scientific leadership, the infrastructure, the collaborative nature, and the collegial environment provided by these programs and affiliated faculty will enable the provision of broad exposure to all trainees to the tenets of basic aging biology as well as to the major tenets of clinical investigation and clinical teaching relevant to older adults across a number of health care disciplines. Specific aims include: 1) the implementation of a rigorous interdisciplinary training program in translational aging research for post-doctoral fellows with MD and PhD degrees through a structured program consisting of a core series of required coursework and interdisciplinary scientific meetings, weekly trainee focused translational aging seminars offered by aging-focused research programs across the Johns Hopkins Medical Institutions, the development of an individualized training program, and a series of leadership and career development seminars that will help to ensure future leadership in this important area of investigation; 2) the provision of trainees with a primary directed translational aging laboratory or clinically oriented research project in collaboration with an experienced mentor with research resources; 3) the provision of trainees with access to the robust interdisciplinary and translation-focused aging research infrastructure and collaborative research opportunities available across the Johns Hopkins Medical Institutions. At the end of this training program, trainees will have a broad interdisciplinary knowledge of basic aging biology and major clinical issues facing older adults, a broad knowledge of translational science, and specific research skills will enable successful future academic careers. Further, the trainee will have learned career development and leadership skill sets that will facilitate the future development of influential interdisciplinary translational aging careers and research programs.

患有慢性病、功能和认知功能减退的老年人人数正在增长 在美国和世界各地迅速蔓延。与此同时，人们对……的认识也迅速扩大。 可能影响这些情况的与衰老相关的生物学变化。尽管有这些平行的趋势，但必须 迄今为止，这种新的生物学知识对老年人的健康和福祉的应用微乎其微。一个 约翰·霍普金斯大学的跨学科老化研究专业知识和基础设施已经形成了临界量 这大大提高了教职员工和实习生的翻译能力。然而， 对于对翻译老龄化研究感兴趣的博士后研究员，工资支持方面的一个显著差距已经放缓 在这一关键的调查领域，培养一支训练有素的科学队伍。《翻译》 这里介绍的老龄化研究培训计划将有助于填补培训中的一个关键空白。这一发展 将通过一系列课堂和体验式学习机会提供专业知识 来自约翰霍普金斯大学已经存在的突出的以老龄化为重点的研究和培训计划 大学。科学的领导力、基础设施、协作性和大学环境 由这些计划和附属教员提供，将使所有受训人员能够广泛接触到 基础衰老生物学原理及临床研究和临床教学的主要原理 与许多医疗保健学科中的老年人相关。具体目标包括：1) 在博士后翻译衰老研究中实施严格的跨学科培训计划 拥有医学博士学位和博士学位的研究员通过一个结构化的计划，该计划由一系列必需的核心 课程和跨学科的科学会议，每周以实习生为重点的翻译老化研讨会 由约翰·霍普金斯医疗机构的以衰老为重点的研究项目提供的研究成果 个性化培训计划，以及一系列领导力和职业发展研讨会，这些研讨会将 帮助确保今后在这一重要调查领域发挥领导作用；2)向受训人员提供 主要指导的转化型衰老实验室或临床导向的研究项目 有经验的导师和研究资源；3)为受训人员提供接触强健的 跨学科和以翻译为重点的老龄化研究基础设施和合作研究机会 在约翰·霍普金斯医疗机构提供。在本培训计划结束时，学员将拥有 对老年人面临的基本衰老生物学和主要临床问题有广泛的跨学科知识， 翻译科学知识和特定的研究技能将使未来的学术事业取得成功。 此外，实习生将学到职业发展和领导技能，这将促进未来 发展有影响力的跨学科翻译老龄化事业和研究计划。