Alcohol consumption and related comorbid conditions: health state utilities for economic evaluation in the context of the COVID-19 pandemic

项目摘要/摘要 新冠肺炎疫情创造了前所未有的社会和卫生环境 以及震级。对健康的影响包括轻微到严重感染SARS-CoV-2；来自 经历大流行，包括焦虑和抑郁；失业、食物带来的情绪压力 不安全和照顾；以及由于实际距离和限制而减少的社会福利 有动静。与此同时，酒类销售一直在增加，许多州都保护了获得 通过宣布餐馆和酒类商店为基本业务并授权非营业场所来提供酒精 酒精外卖、混合饮料外带和路边取货。饮酒和饮酒之间的相互作用 新冠肺炎大流行的影响尚不清楚：消费可能正在发生变化，以应对 新冠肺炎环境和危险饮酒可能会增加，对健康造成负面后果 而幸福感或消费变化可能仅限于低风险的一端，很少或根本没有 对幸福的影响。这项研究将对美国人口进行3次连续的横断面调查 评估酒精消费、健康相关生活质量(HRQOL)和COVID的代表性样本- 在个人层面上的相关情况。生成的数据集将允许对关联进行估计 不同新冠肺炎体验条件下饮酒与HRQOL之间的关系。会的 允许跨种群亚群检查潜在的异质性--不同的新冠肺炎条件， 不同的消费方式，以及两者不同的效果。这项研究还将比较COVID之前和期间的情况 使用NESARC-III之前的美国数据作为基准的消费和HRQOL，反映了#年的人口模式 2013-14年间。由于新冠肺炎疫情是一个高度动态的局势，收集美国的数据很重要 人口数据现在可以在反应的早期阶段为行为提供信息。我们的结果将为酒精政策提供信息 并将能够根据正在进行的大流行对酒精干预措施进行准确评估。

Project Summary/Abstract The COVID-19 pandemic has created a social and health environment that is previously unknown in scope and magnitude. Health effects include mild to severe infection with SARS-coV-2; psychological trauma from living through a pandemic, including anxiety and depression; emotional stress from unemployment, food insecurity, and caretaking; and diminished social well-being due to physical distancing and restrictions in movement. At the same time, alcohol sales have been increasing, and many states have protected access to alcohol through declaring restaurants and liquor stores as essential businesses and authorizing off-premise alcohol deliveries, mixed drinks to-go, and curbside pickup. The interplay between alcohol consumption and the effects of the COVID-19 pandemic are as yet unknown: consumption may be changing in response to COVID-19 circumstances and hazardous drinking may be increasing with negative consequences on health and well-being, or consumption changes may be limited to the low-risk end of the spectrum with little or no effect on well-being. This study will conduct 3 successive cross-sectional surveys of a US population representative sample to assess alcohol consumption, health-related quality of life (HRQoL), and COVID- related conditions at an individual level. The resultant dataset will allow for estimates of the association between alcohol consumption and HRQoL while under different conditions of COVID-19 experiences. It will allow examination of potential heterogeneity across population subgroups—varying COVID-19 conditions, varying consumption, and varying effects of the two. The study will also compare pre and during COVID consumption and HRQoL using prior US data from NESARC-III as a baseline, reflecting population patterns in the 2013-14 period. As the COVID-19 pandemic is a highly dynamic situation, it is important to collect US population data now to inform behavior in the early stages of response. Our results will inform alcohol policy and will enable accurate evaluation of alcohol interventions in light of the ongoing pandemic.