Alcohol consumption and related comorbid conditions: health state utilities for economic evaluation in the context of the COVID-19 pandemic

项目总结/摘要 2019冠状病毒病大流行创造了一个前所未有的社会和健康环境 和规模。对健康的影响包括轻度到重度的SARS-coV-2感染; 生活在流行病中，包括焦虑和抑郁;失业，食物 不安全和照顾;以及由于身体距离和限制而减少的社会福祉， 运动与此同时，酒精销售一直在增加，许多州都保护了获得酒精的机会。 通过宣布餐馆和酒类商店为基本业务，并授权场外经营， 送酒外卖混合饮料路边取货酒精消费和 COVID-19大流行的影响尚不清楚：消费可能会因 COVID-19情况和危险饮酒可能会增加，对健康产生负面影响 和福祉，或消费变化可能仅限于低风险端的频谱，很少或没有 对幸福的影响。这项研究将对美国人口进行3次连续的横断面调查 代表性样本，以评估酒精消费，健康相关的生活质量（HRQoL），和COVID- 个人层面的相关问题。由此产生的数据集将允许估计的关联 饮酒与HRQoL之间的关系。它将 允许检查人群亚组之间的潜在异质性-不同的COVID-19状况， 不同的消耗量，以及两者的不同影响。该研究还将比较COVID前和COVID期间 使用NESAR-III的既往美国数据作为基线，反映以下人群模式： 2013-14年期间。由于COVID-19大流行是一个高度动态的情况，因此收集美国 人口数据现在可以在反应的早期阶段告知行为。我们的研究结果将为酒精政策提供信息 并将能够根据正在发生的流行病准确评估酒精干预措施。

Project Summary/Abstract The COVID-19 pandemic has created a social and health environment that is previously unknown in scope and magnitude. Health effects include mild to severe infection with SARS-coV-2; psychological trauma from living through a pandemic, including anxiety and depression; emotional stress from unemployment, food insecurity, and caretaking; and diminished social well-being due to physical distancing and restrictions in movement. At the same time, alcohol sales have been increasing, and many states have protected access to alcohol through declaring restaurants and liquor stores as essential businesses and authorizing off-premise alcohol deliveries, mixed drinks to-go, and curbside pickup. The interplay between alcohol consumption and the effects of the COVID-19 pandemic are as yet unknown: consumption may be changing in response to COVID-19 circumstances and hazardous drinking may be increasing with negative consequences on health and well-being, or consumption changes may be limited to the low-risk end of the spectrum with little or no effect on well-being. This study will conduct 3 successive cross-sectional surveys of a US population representative sample to assess alcohol consumption, health-related quality of life (HRQoL), and COVID- related conditions at an individual level. The resultant dataset will allow for estimates of the association between alcohol consumption and HRQoL while under different conditions of COVID-19 experiences. It will allow examination of potential heterogeneity across population subgroups—varying COVID-19 conditions, varying consumption, and varying effects of the two. The study will also compare pre and during COVID consumption and HRQoL using prior US data from NESARC-III as a baseline, reflecting population patterns in the 2013-14 period. As the COVID-19 pandemic is a highly dynamic situation, it is important to collect US population data now to inform behavior in the early stages of response. Our results will inform alcohol policy and will enable accurate evaluation of alcohol interventions in light of the ongoing pandemic.