Alcohol consumption and related comorbid conditions: health state utilities for economic evaluation

酒精消费和相关合并症:用于经济评估的健康状况公用事业

基本信息

  • 批准号:
    10426403
  • 负责人:
  • 金额:
    $ 8.21万
  • 依托单位:
  • 依托单位国家:
    美国
  • 项目类别:
  • 财政年份:
    2019
  • 资助国家:
    美国
  • 起止时间:
    2019-09-05 至 2022-11-30
  • 项目状态:
    已结题

项目摘要

PROJECT SUMMARY Effective prevention and treatment of alcohol use disorder (AUD) in the US could save more than 80,000 lives each year. Although abstinence has traditionally been the goal of AUD interventions, reductions in drinking levels have been shown to decrease the harms of AUD, providing an additional “goal post” for prevention and treatment. At the same time, patient-centered care and patient-reported outcomes are having a greater impact on health care decision-making than ever before. Thus, there is an urgent need for rigorous alcohol health services research to inform practice and policy. Moreover, it is critical that this research parallel medically-focused health services research to solidify a “level playing field” in comparative assessments for resource allocation decisions. Increasingly these resource allocation decisions are informed by cost-effectiveness analyses that use health utility as an outcome. Health utility captures individuals’ preferences for living in a given health state and is the foundation of quality adjusted life years (QALYs), the preferred outcome measure for cost-effectiveness analysis. Health utilities and QALYs are rarely used by alcohol health services researchers, however. The lack of health utilities for alcohol health states is a critical shortcoming in alcohol health services research that disadvantages alcohol services in resource allocation decisions. To promote the use of health utilities in alcohol health services research, we will conduct secondary data analyses of the National Epidemiologic Survey on Alcohol and Related Conditions-III (NESARC-III) to address the following specific aims: Aim 1: Estimate health state utilities for AUD health states stratified by alcohol consumption levels. 1.1 Estimate mean utility and variance for AUD health states based on DSM-5 severity and WHO risk levels. 1.2 Test utility differences between adjacent health states to inform the impact of reductions in AUD severity and/or consumption levels. Aim 2: Empirically and predictively derive joint health state utilities for AUD with comorbid conditions. 2.1 Estimate mean utility and variance for past year AUD with select comorbid conditions. 2.2 Test the performance of predictive algorithms for estimating joint health state utilities in AUD. As an AREA project, we will involve graduate and undergraduate students in all aspects of the study as integral members of the research team, providing intensive exposure to and training in research. We will disseminate our results to the clinical, practice, policy, and research communities to advance the use of health utility in alcohol health services research. Our findings will result in broader use of health utilities and QALYs for policy and clinical decision making in alcohol health services, and thereby lead to improved patient and population health. 1
项目总结

项目成果

期刊论文数量(4)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
Association of opioid utilization management with prescribing and overdose.
  • DOI:
    10.37765/ajmc.2022.88829
  • 发表时间:
    2022-02-01
  • 期刊:
  • 影响因子:
    0
  • 作者:
    Andersen MS;Lorenz V;Pant A;Bray JW;Alexander GC
  • 通讯作者:
    Alexander GC
Estimating Joint Health State Utility Algorithms Under Partial Information.
  • DOI:
    10.1016/j.jval.2022.09.009
  • 发表时间:
    2023-05
  • 期刊:
  • 影响因子:
    4.5
  • 作者:
    Bray, Jeremy W.;Thornburg, Benjamin D.;Gebreselassie, Abraham W.;LaButte, Collin A.;Barbosa, Carolina;Wittenberg, Eve
  • 通讯作者:
    Wittenberg, Eve
Health Utility of Drinkers' Family Members: A Secondary Analysis of a US Population Data Set.
  • DOI:
    10.1177/23814683221128507
  • 发表时间:
    2022-07
  • 期刊:
  • 影响因子:
    0
  • 作者:
    Thornburg, Benjamin;Bray, Jeremy W.;Wittenberg, Eve
  • 通讯作者:
    Wittenberg, Eve
Alcohol consumption and health-related quality of life in the US during the COVID-19 pandemic: a US national survey.
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JEREMY W BRAY其他文献

JEREMY W BRAY的其他文献

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{{ truncateString('JEREMY W BRAY', 18)}}的其他基金

Alcohol consumption and related comorbid conditions: health state utilities for economic evaluation in the context of the COVID-19 pandemic
酒精消费和相关合并症:在 COVID-19 大流行背景下进行经济评估的健康状况公用事业
  • 批准号:
    10193124
  • 财政年份:
    2019
  • 资助金额:
    $ 8.21万
  • 项目类别:
Data Coordinating Center for the Work, Family and Health Network
工作、家庭和健康网络数据协调中心
  • 批准号:
    7769903
  • 财政年份:
    2005
  • 资助金额:
    $ 8.21万
  • 项目类别:
Data Coordinating Center for the Work, Family and Health Network
工作、家庭和健康网络数据协调中心
  • 批准号:
    7562831
  • 财政年份:
    2005
  • 资助金额:
    $ 8.21万
  • 项目类别:
Workplace Policies and Practices Coordinating Center
工作场所政策和实践协调中心
  • 批准号:
    7105494
  • 财政年份:
    2005
  • 资助金额:
    $ 8.21万
  • 项目类别:
Workplace Policies and Practices Coordinating Center
工作场所政策和实践协调中心
  • 批准号:
    7691675
  • 财政年份:
    2005
  • 资助金额:
    $ 8.21万
  • 项目类别:
Data Coordinating Center for the Work, Family and Health Network
工作、家庭和健康网络数据协调中心
  • 批准号:
    8046415
  • 财政年份:
    2005
  • 资助金额:
    $ 8.21万
  • 项目类别:
Workplace Policies and Practices Coordinating Center
工作场所政策和实践协调中心
  • 批准号:
    7280285
  • 财政年份:
    2005
  • 资助金额:
    $ 8.21万
  • 项目类别:
Data Coordinating Center for the Work, Family and Health Network
工作、家庭和健康网络数据协调中心
  • 批准号:
    8220985
  • 财政年份:
    2005
  • 资助金额:
    $ 8.21万
  • 项目类别:
Workplace Policies and Practices Coordinating Center
工作场所政策和实践协调中心
  • 批准号:
    7003618
  • 财政年份:
    2005
  • 资助金额:
    $ 8.21万
  • 项目类别:
Alcohol Screening and Brief Intervention in an EAP
EAP 中的酒精筛查和简短干预
  • 批准号:
    6827643
  • 财政年份:
    2004
  • 资助金额:
    $ 8.21万
  • 项目类别:
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