Basic Immunology Training Program

项目总结 杜克大学免疫学研究生计划建议继续其基础免疫学 培训计划。培训计划的主要目标是选拔有才华的博士后候选人和 通过正式的课程作业、研讨会和独立研究，为杰出和 在基础免疫学方面从事富有成效的研究工作。培训教师由32名免疫学家组成，他们持有 免疫学系的初级或二级职位。这个教员为实习生提供 在当代免疫学研究的一系列领域接受严格培训的机会，例如： 淋巴细胞和髓系细胞发育和功能的机制，包括谱系决定，V(D)J 重组，类交换重组，体细胞超突变，细胞信号，效应细胞分化， 淋巴细胞和髓系细胞动态平衡、免疫记忆和免疫耐受；机制 先天免疫和炎症，包括巨噬细胞、树突状细胞、肥大细胞和补体功能； 细菌、病毒和真菌病原体的宿主防御机制；自身免疫；抗肿瘤免疫； 神经免疫学；以及疫苗开发。正在寻求资金支持四名博士后的培训 每年的学生人数。遴选委员会将选出最杰出的二年级和三年级博士后 免疫学研究生项目的学员通过培训项目获得支持。特别强调将 将重点放在招聘和甄选优秀的、任职人数不足的少数族裔受训人员方面。小心翼翼的 精心设计的核心课程将为学员提供基础免疫学、生物化学、细胞 生物学、分子生物学和遗传学。受训者将接受正式的研究道德培训，以确保 他们将以最高的学术诚信标准进行研究。还将为学员提供 一系列的职业发展机会，使他们能够最好地利用他们的培训 富有成效和回报的职业道路。

PROJECT SUMMARY The Duke University Graduate Program in Immunology proposes a continuation of its Basic Immunology Training Program. The main objective of the Training Program is to select talented predoctoral candidates and to prepare them, through formal coursework, seminars and independent research, for outstanding and productive research careers in basic immunology. The training faculty consists of 32 immunologists who hold primary or secondary appointments in the Department of Immunology. This faculty provides trainees with opportunities for rigorous training in a range of areas of contemporary immunologic research, for example: mechanisms of lymphocyte and myeloid cell development and function, including lineage determination, V(D)J recombination, class switch recombination, somatic hypermutation, cell signaling, effector cell differentiation, lymphocyte and myeloid cell homeostasis, immunological memory and immunological tolerance; mechanisms of innate immunity and inflammation, including macrophage, dendritic cell, mast cell and complement function; mechanisms of host defense against bacterial, viral and fungal pathogens; autoimmunity; anti-tumor immunity; neuroimmunology; and vaccine development. Funds are sought to support the training of four predoctoral students per year. A selections committee will choose the most outstanding second and third year predoctoral trainees in the Graduate Program in Immunology for support by the Training Program. Special emphasis will be placed on the recruitment and selection of outstanding underrepresented minority trainees. A carefully crafted core curriculum will provide trainees with superb grounding in basic immunology, biochemistry, cell biology, molecular biology and genetics. Trainees will receive formal training in research ethics to insure that they will conduct their research with the highest standards of academic integrity. Trainees will also be provided a range of career development opportunities so that they are best equipped to parlay their training into productive and rewarding career paths.