Basic Immunology

描述（由申请人提供）：杜克大学免疫学研究生课程建议继续其基础免疫学培训计划。培训计划的主要目标是选择有才华的博士前候选人，并通过正式课程，研讨会和独立研究为他们在基础免疫学领域的杰出和富有成效的研究事业做好准备。培训教师由22名免疫学家组成，他们在免疫学系担任初级或二级职位。本系为受训者提供了在一系列当代免疫学研究领域进行严格训练的机会，例如：淋巴细胞发育和功能的机制，包括淋巴细胞谱系承诺、V(D)J重组、淋巴细胞信号传导、效应细胞发育、稳态和耐受性；先天免疫和炎症的机制，包括巨噬细胞、树突状细胞、肥大细胞和补体功能；宿主对细菌和病毒病原体的防御机制自身免疫和免疫缺陷疾病的发展；抗肿瘤免疫。正在寻求资金，以支持每年培训四名学生。一个遴选委员会将从接受免疫学研究生课程的学生中选出最优秀的博士预科学员。这些学生将在第一年和第二年获得支持，直到他们获得博士候选人资格和开始论文研究。精心设计的核心课程将为学员提供基础免疫学，细胞生物学，分子生物学和遗传学的精湛基础。基础免疫学培训计划将教授下一代美国研究人员进行杰出基础免疫学研究所需的关键技能。这些研究人员未来的发现将对我们在对抗传染病、癌症、自身免疫和免疫缺陷疾病方面的持续进步至关重要。

DESCRIPTION (provided by applicant): The Duke University Graduate Program in Immunology proposes a continuation of its Basic Immunology Training Program. The main goal of the Training Program is to select talented predoctoral candidates and to prepare them, through formal coursework, seminars, and independent research, for outstanding and productive research careers in basic immunology. The training faculty consists of 22 immunologists who hold primary or secondary appointments in the Department of Immunology. This faculty provides trainees with opportunities for rigorous training in a range of areas of contemporary immunologic research, for example: mechanisms of lymphocyte development and function, including lymphoid lineage commitment, V(D)J recombination, lymphocyte signaling, effector cell development, homeostasis, and tolerance; mechanisms of innate immunity and inflammation, including macrophage, dendritic cell, mast cell and complement function; mechanisms of host defense against bacterial and viral pathogens; the development of autoimmune and immunodeficiency diseases; and anti-tumor immunity. Funds are sought to support the training of four students per year. A selections committee will choose for support the most outstanding predoctoral trainees from among students accepted into the Graduate Program in Immunology. These students will receive support during their first and second years, until their admission to doctoral candidacy and the initiation of dissertation research. A carefully crafted core curriculum will provide trainees with superb grounding in basic immunology, cell biology, molecular biology and genetics. The Basic Immunology Training Program will teach the next generation of U.S. researchers the critical skills they will need to perform outstanding basic immunologic research. Future discoveries by these researchers will be absolutely essential for our continued progress in the fights against infectious diseases, cancer, and autoimmune and immunodeficiency diseases.