Basic Immunology Training Program

基础免疫学培训计划

• 批准号: 10380782
• 负责人: Michael S Krangel
• 金额: $ 20.75万
• 依托单位: DUKE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2002
• 资助国家: 美国
• 起止时间: 2002-07-01 至 2025-05-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10380782
• 关键词: Immunology; Training Programs

PROJECT SUMMARY The Duke University Graduate Program in Immunology proposes a continuation of its Basic Immunology Training Program. The main objective of the Training Program is to select talented predoctoral candidates and to prepare them, through formal coursework, seminars and independent research, for outstanding and productive research careers in basic immunology. The training faculty consists of 32 immunologists who hold primary or secondary appointments in the Department of Immunology. This faculty provides trainees with opportunities for rigorous training in a range of areas of contemporary immunologic research, for example: mechanisms of lymphocyte and myeloid cell development and function, including lineage determination, V(D)J recombination, class switch recombination, somatic hypermutation, cell signaling, effector cell differentiation, lymphocyte and myeloid cell homeostasis, immunological memory and immunological tolerance; mechanisms of innate immunity and inflammation, including macrophage, dendritic cell, mast cell and complement function; mechanisms of host defense against bacterial, viral and fungal pathogens; autoimmunity; anti-tumor immunity; neuroimmunology; and vaccine development. Funds are sought to support the training of four predoctoral students per year. A selections committee will choose the most outstanding second and third year predoctoral trainees in the Graduate Program in Immunology for support by the Training Program. Special emphasis will be placed on the recruitment and selection of outstanding underrepresented minority trainees. A carefully crafted core curriculum will provide trainees with superb grounding in basic immunology, biochemistry, cell biology, molecular biology and genetics. Trainees will receive formal training in research ethics to insure that they will conduct their research with the highest standards of academic integrity. Trainees will also be provided a range of career development opportunities so that they are best equipped to parlay their training into productive and rewarding career paths.

项目摘要 杜克大学免疫学研究生课程建议继续其基础免疫学 培训计划。培训计划的主要目标是选择有才华的博士前候选人， 通过正式的课程，研讨会和独立研究，为他们做好准备， 在基础免疫学方面的研究成果。培训教师由32名免疫学家组成， 免疫学系的主要或次要任命。该学院为学员提供 在当代免疫学研究的一系列领域进行严格培训的机会，例如： 淋巴细胞和骨髓细胞发育和功能的机制，包括谱系确定，V（D）J 重组，类别转换重组，体细胞超突变，细胞信号传导，效应细胞分化， 淋巴细胞和骨髓细胞稳态，免疫记忆和免疫耐受;机制 天然免疫和炎症，包括巨噬细胞、树突状细胞、肥大细胞和补体功能; 宿主对细菌、病毒和真菌病原体的防御机制;自身免疫;抗肿瘤免疫; 神经免疫学和疫苗开发。寻求资金支持四个博士前的培训 学生每年。选拔委员会将选择最优秀的第二和第三年的博士预科 免疫学研究生课程的受训人员，以获得培训计划的支持。将特别强调 在征聘和甄选代表性不足的优秀少数群体受训人员方面，应将工作重点放在这方面。一个精心 精心设计的核心课程将为学员提供基础免疫学，生物化学，细胞 生物学、分子生物学和遗传学。受训人员将接受研究伦理方面的正式培训，以确保 他们将以最高的学术诚信标准进行研究。还将向受训人员提供 一系列的职业发展机会，使他们能够最好地利用他们的培训， 富有成效和回报的职业道路。