EOSC4Cancer: A European-wide foundation to accelerate Data-driven Cancer Research

癌症的复杂性需要跨越国界整合先进的研究数据，以实现进展。事实上，“地平线欧洲”癌症任务委员会已经确定，通过联邦基础设施在整个欧洲研究区访问数据、知识和数字服务，是成功的关键促成条件。我们越好地组织整个欧洲的癌症数据，我们就能更好、更快地将新的生物和技术创新成果带给欧盟公民/患者。EOSC4Cancer将使癌症基因组学、成像、医学、临床、环境和社会经济学数据可访问，使用和增强现有的联合和可互操作系统，以安全地识别、共享、处理和重用FAIR癌症数据，并将通过社区驱动的分析环境提供这些数据。提供精心策划的数据集对于高级分析和计算方法（包括机器学习和人工智能方法）的可重复性和鲁棒性至关重要。eosc4癌症用例将涵盖从癌症预防到诊断再到治疗的患者旅程，为未来癌症任务项目的数据轨迹和工作流程奠定基础。EOSC4Cancer汇集了来自14个欧洲国家的癌症研究中心、研究基础设施、领先研究小组、医院和超级计算中心的综合联盟。为了使发展可持续，这些将作为研究基础设施合作伙伴服务组合的一部分提供，与EOSC生态系统相关，并为欧洲癌症使命服务，这将通过与大型国际联盟的合作成为可能，例如ICGC-Argo， GA4GH, 1+MG/B1MG，欧洲癌症核心，欧洲癌症信息系统，欧洲癌症登记处网络，抗癌行动创新伙伴关系联合行动和患者/幸存者协会。

Cancer complex nature requires integration of advanced research data across national boundaries to enable progress. Indeed, the Horizon Europe mission board for cancer has identified access to data, knowledge and digital services - accessible across the European Research Area through federated infrastructures - as a key enabling condition for success. The better we organise cancer data across Europe, the better and faster we can bring the fruits of new biological and technical innovations to the benefit of EU citizens/patients. EOSC4Cancer will make cancer genomics, imaging, medical, clinical, environmental and socio-economics data accessible, using and enhancing existing federated and interoperable systems for securely identifying, sharing, processing and reusing FAIR cancer data across borders, and it will offer them via community-driven analysis environments. EOSC4Cancer provision of well curated datasets will be essential for advanced analytics and computational methods to be reproducible and robust, including machine learning and artificial intelligence approaches. EOSC4Cancer use-cases will cover the patient journey from cancer prevention to diagnosis to treatment, laying the foundation of data trajectories and workflows for future cancer mission projects. EOSC4Cancer brings together a comprehensive consortium of cancer research centres, research infrastructures, leading research groups, hospitals and supercomputing centres from 14 European countries. To make the developments sustainable, these will be offered as part of the research infrastructures partners services portfolio, in connection with the EOSC ecosystem and to serve the European Cancer Mission, which will be possible via the engagement with large international coalitions, e.g. ICGC-Argo, GA4GH, 1+MG/B1MG, Cancer Core Europe, European Cancer Information System, European Network of Cancer Registries, Innovative Partnership for Action Against Cancer Joint Action and patients/survivors associations.