Administrative Core

行政核心

• 批准号: 10197803
• 负责人: GREGORY E. SIMON
• 金额: $ 102.4万
• 依托单位: KAISER FOUNDATION RESEARCH INSTITUTE
• 依托单位国家: 美国
• 财政年份: 2019
• 资助国家: 美国
• 起止时间: 2019-09-23 至 2024-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10197803
• 关键词: Address; Advisory Committees; Antipsychotic Agents; Clinical; Clinical Research; Collaborations; Communication; Communication Tools; Data; Evaluation; Family; Funding; Goals; Health Services Research; Health system; Infrastructure Activities; Integrated Health Care Systems; Lead; Learning; Libraries; Machine Learning; Mental Depression; Mental Health; Methods; National Institute of Mental Health; Network Infrastructure; Network-based; Observational epidemiology; Occupational activity of managing finances; Organization administrative structures; Patients; Pilot Projects; Practice based research; Primary Health Care; Process; Qualitative Research; Quality Control; Reaction Time; Request for Applications; Research; Research Infrastructure; Research Methodology; Research Personnel; Research Priority; Research Project Grants; Resource Sharing; Resources; Site; Software Tools; Specific qualifier value; Speed; Strategic Planning; Structure; Suicide prevention; Supervision; Trust; Youth; computable phenotypes; data infrastructure; first episode psychosis; health care delivery; implementation science; improved; large scale data; member; next generation; open source; operation; outreach; patient engagement; patient population; practice-based research network; pragmatic trial; programs; response; success

We propose to expand the existing Mental Health Research Network (MHRN) to include 14 research centers embedded in large health systems serving over 25 million patients in 16 states. Existing MHRN infrastructure will be enhanced to support a next-generation practice-based network, including: • Increased engagement of patients, health system leaders, and other stakeholders in network governance and selection of research priorities • An expanded public, open-source library of software tools and other technical resources • More formal processes for conducting feasibility pilot projects and rapid response to stakeholder queries • Expanded outreach to external stakeholders and research partners This overall application requests support for an Administrative Core, a Methods core, two Signature research projects and two Pilot research projects. The Administrative Core, led by Gregory Simon and Belinda Operskalski, will include an Organizational Unit responsible for governance, strategic planning, fiscal management, and compliance; an Outreach and External Collaboration Unit responsible for communications, resource sharing, promoting new collaborations, and supporting feasibility pilot projects; and an Emerging Issues Unit to identify and address emerging questions for internal and external stakeholders. The Organizational Unit will maintain and enhance the governance, operational, fiscal management, and compliance resources proven successful in 8 years of MHRN operations. At each site, core resources will support effort by a site lead investigator (responsible for supervising local data infrastructure activities and health system engagement), one or more programmer/analysts (responsible for data infrastructure quality control, routine descriptive analyses, and analyses regarding emerging issues), and one or more project managers (responsible for local financial management and regulatory compliance). In the proposed new funding cycle, patient and family stakeholders will join the network Steering Committee and an External Advisory Committee will participate in network strategic planning and evaluation. The Outreach and External Collaboration unit will maintain and enhance the communications tools, resource sharing mechanisms, health system engagement processes, and external investigator engagement processes proven successful in 8 years of MHRN operation. A structured process for receiving and responding to requests for feasibility or pilot data (from either MHRN-based or external investigators) will include a transparent process for timely response to queries and specific resources allocated to small pilot projects. A structured process for receiving and responding to queries from health system and external stakeholders will include technical assistance to end- users and will draw from MHRN's large library of descriptive analyses, standard queries, and computable phenotypes.

我们建议将现有的精神卫生研究网络(MHRN)扩大到包括14个研究中心 嵌入大型医疗系统，为16个州的2500多万名患者提供服务。现有的MHRN基础设施 将得到增强，以支持基于实践的下一代网络，包括： ·患者、卫生系统领导人和其他利益相关者更多地参与网络治理 和研究优先事项的选择 ·扩大软件工具库和其他技术资源的公共开放源码库 ·开展可行性试点项目和快速回应利益攸关方询问的更正式程序 ·扩大与外部利益攸关方和研究伙伴的联系 此整体应用程序请求支持一个管理核心、一个方法核心、两个签名研究 项目和两个试点研究项目。由格雷戈里·西蒙和贝琳达领导的行政核心 Operskalski，将包括一个组织股，负责治理、战略规划、财政 管理、合规；一个负责沟通的外联和外部协作股， 资源共享，促进新的协作，支持可行性试点项目；以及新兴的 问题股，为内部和外部利益攸关方确定和解决新出现的问题。这个 组织单位将维持和加强治理、业务、财政管理和 合规资源在8年的MHRN运营中被证明是成功的。在每个站点，核心资源将 现场首席调查员的支持工作(负责监督本地数据基础设施活动和 医疗系统项目)、一名或多名程序员/分析师(负责数据基础设施质量 控制、例行描述性分析和关于新出现问题的分析)，以及一个或多个项目 管理人员(负责当地财务管理和监管合规)。在建议的新的 资金周期，患者和家庭利益相关者将加入网络指导委员会和外部 咨询委员会将参与网络战略规划和评估。外展与外展 协作股将维护和加强沟通工具、资源共享机制、健康 系统接洽流程和外部调查员接洽流程在8年内证明是成功的 MHRN手术的一部分。用于接收和响应可行性或试点数据请求的结构化流程 (来自人权局或外部调查人员)将包括一个透明的程序，以便及时应对 查询和分配给小型试点项目的具体资源。一个结构化的流程，用于接收和 答复卫生系统和外部利益攸关方的询问将包括提供技术援助，以结束 并将从MHRN的描述性分析、标准查询和可计算的大型库中提取 表型。