Strengthening regional stem cells based research for advancement of multi modal innovative strategy for modelling neurodevelopmental disorders

由大脑发育早期改变引起的神经发育障碍(NDDS)是一组复杂的异质性疾病，会导致自闭症谱系障碍、智力残疾、精神分裂症和双相情感障碍等精神疾病。NDDS具有很高的社会经济影响，患有NDDS和精神健康问题的患者在地理上分散。因此，需要建立具有同等研究能力和业务守则的高能力区域中心，以便开展全球研究活动。Streamline的目标是加强战略网络，加强分子遗传学和基因工程研究所的研究和创新潜力，以便将分子遗传学和基因工程研究所发展成为西巴尔干地区研究非传统药物的高能力中心，从而能够与欧洲的类似中心相结合。这将通过将IMGGE与欧洲三家一流的研究机构结成伙伴关系来实现：卡迪夫大学、马斯特里赫特大学和研究与技术中心。该项目的目标是：a)加强目前的联系，并扩大该机构与国际领先的欧洲伙伴和区域伙伴之间的整体战略联网活动；b)提高该机构在非数字发展领域的研究人员的研究形象和科学吸引力；c)加强该机构工作人员的研究管理能力和行政技能；d)成为应对非数字发展问题的创新方面的区域领导者。将通过联网、工作人员交流、培训、暑期学校、研讨会、讲习班、参加会议和在科学界、工业界和公众中传播来实现这些目标。与合作伙伴结对将提供获得新的研究途径、创造力、开发新方法和增加合格科学家的流动性(向内和向外)的机会。

Neurodevelopmental disorders (NDDs) caused by alterations in early brain development are a group of complex and heterogeneous disorders that give rise to the psychiatric conditions such as autism spectrum disorders, intellectual disability, schizophrenia and bipolar disorder. NDDs have a high socio-economic impact and patients with NDDs and mental health problems are geographically dispersed. Thus, establishment of high capacity regional centres with equivalent research capacity and codes of practice is needed in order to build global research activity. The goals of STREAMLINE are to enhanced strategic networking and reinforce research and innovation potential of the Institute of Molecular Genetics and Genetic Engineering (IMGGE) in order to develop IMGGE as a high capacity hub for research of NDDs in the Western Balkans which is able to integrate with similar centres in Europe. This will be achieved by twinning IMGGE with three top-class research institutions in Europe: Cardiff University, University of Maastricht and Centre for Research and Technology. The project objectives are: a) to enhance the current and scale up the overall strategic networking activities between the IMGGE and internationally-leading European partners and regional partners; b) to raise the research profile of research stuff and scientific attractiveness of IMGGE in the field of NDDs; c) to strengthens research management capacities and administrative skills of the IMGGE staff and d) to become a regional leader in innovations tackling NDDs. Objectives will be achieved through networking, staff exchanges, training, summer schools, symposia, workshops, participation at conferences and dissemination in scientific community, industries and public. Twinning with partners will provide access to new research avenues, creativity, development of new approaches and increased mobility (inwards and outwards) of qualified scientists.