The Cirrhosis Medical Home: A Feasibility Study
肝硬化医疗之家:可行性研究
基本信息
- 批准号:10202587
- 负责人:
- 金额:$ 12.15万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2020
- 资助国家:美国
- 起止时间:2020-07-01 至 2023-04-30
- 项目状态:已结题
- 来源:
- 关键词:AcuteAddressAmericanAscitesBehavioralCaringChronic DiseaseCirrhosisClinicalCognitiveCommunitiesComplexComputer softwareCustomDataData CollectionDementiaDevelopmentDropoutEnrollmentEnsureFeasibility StudiesFeedbackFrail ElderlyFutureGastrointestinal HemorrhageGoalsHealthcare SystemsHepatic EncephalopathyHomeHospitalizationHospitalsImpairmentIndianaIndividualInfectionInpatientsInstitute of Medicine (U.S.)InterventionLeadLength of StayLiver CirrhosisMeasuresMedicalMental DepressionModelingMorbidity - disease rateNatureOutcomeOutcome AssessmentPatient CarePatient-Centered CarePatientsPhysical FunctionPopulationPreparationProcessProtocols documentationQuality of lifeRandomized Clinical TrialsRandomized Controlled TrialsResearch PersonnelResourcesSocial FunctioningSocietiesSymptomsTestingUnited States Centers for Medicare and Medicaid ServicesUniversitiesVulnerable Populationsbiopsychosocialcare coordinationchronic liver diseasecollaborative carecostdisabilitydisabling symptomefficacy evaluationefficacy trialexperiencehealth care servicehealth care service utilizationhospital readmissionimprovedinnovationmedical schoolsmortalitynovelpatient orientedpatient populationpersonalized carepersonalized interventionpsychologicrandomized trialrehabilitation servicescreeningsuccesstooltreatment as usualtrial comparing
项目摘要
PROJECT SUMMARY
Liver cirrhosis places a significant burden on individuals and society, causing diminished quality of life,
increased disability, morbidity, and mortality; and high costs and utilization of health care resources. These
outcomes could be improved with existing resources, but the current fragmented nature of the health care
system does not allow for the necessary coordination to best care for this population. To address the general
lack of care coordination in the health care system, collaborative care models have been developed for a wide
range of clinical settings, and have successfully improved care for patients with numerous chronic diseases.
Researchers at the Indiana University School of Medicine have over 20 years of experience in developing,
testing, and implementing collaborative care for patients with dementia, depression, and other conditions.
Building on these successes, investigators have customized the collaborative care model to best meet the
unique needs of patients with decompensated cirrhosis: The Cirrhosis Medical Home (CMH). This proposal
aims to establish the feasibility of performing a randomized controlled trial comparing the CMH to usual care
for patients discharged from the hospital with decompensated cirrhosis. The specific aims are: (1) to test the
screening and enrollment processes for a randomized trial of the CMH compared to usual care for patients
discharged from the hospital with decompensated cirrhosis; (2) to assess the data collection process, outcome
assessment, and the acceptability of the CMH randomized trial; and (3) to estimate the effect size of the CMH
intervention on quality of life after six months. Upon completion of the proposed study, the investigators will
have demonstrated the feasibility of enrolling and retaining subjects in a randomized trial of the CMH, and they
will have established an estimated effect size that will ensure adequate power for a future randomized trial that
will evaluate the efficacy of the CMH.
项目摘要
肝硬化给个人和社会带来巨大负担,导致生活质量下降,
残疾、发病率和死亡率增加;医疗保健资源的高成本和高利用率。这些
利用现有资源可以改善结果,但目前医疗保健的分散性
系统不允许进行必要的协调,以最好地照顾这一人口。上发言
由于卫生保健系统缺乏护理协调,协作护理模式已广泛发展,
该公司在一系列临床环境中发挥了重要作用,并成功地改善了对患有多种慢性疾病的患者的护理。
印第安纳州大学医学院的研究人员在开发,
测试,并为患有痴呆症,抑郁症和其他疾病的患者实施合作护理。
在这些成功的基础上,研究人员定制了协作护理模式,以最好地满足
失代偿期肝硬化患者的独特需求:肝硬化医疗之家(CMH)。这项建议
目的是建立一个比较CMH和常规护理的随机对照试验的可行性
失代偿期肝硬化患者出院的治疗方案。具体目的是:(1)检验
CMH与患者常规护理相比的随机试验的筛选和入组过程
失代偿期肝硬化出院;(2)评估数据收集过程、结局
CMH随机试验的可接受性;(3)估计CMH的效应量
6个月后进行生活质量干预。完成拟定研究后,研究者将
已经证明了在CMH的随机试验中招募和保留受试者的可行性,
将确定估计的效应量,以确保未来随机试验具有足够的把握度,
将评估CMH的疗效。
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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Eric Orman其他文献
Eric Orman的其他文献
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{{ truncateString('Eric Orman', 18)}}的其他基金
The Transitional Liver Clinic (TLC): Reducing Liver Disease Readmission
过渡肝脏诊所 (TLC):减少肝病再入院
- 批准号:
10587530 - 财政年份:2023
- 资助金额:
$ 12.15万 - 项目类别:
The Cirrhosis Medical Home: A Feasibility Study
肝硬化医疗之家:可行性研究
- 批准号:
9978477 - 财政年份:2020
- 资助金额:
$ 12.15万 - 项目类别:
Unplanned Early Readmissions of Hospitalized Patients with Cirrhosis
住院肝硬化患者的意外提前再入院
- 批准号:
9353422 - 财政年份:2016
- 资助金额:
$ 12.15万 - 项目类别:
Unplanned Early Readmissions of Hospitalized Patients with Cirrhosis
住院肝硬化患者的意外提前再入院
- 批准号:
9767124 - 财政年份:2016
- 资助金额:
$ 12.15万 - 项目类别:
Unplanned Early Readmissions of Hospitalized Patients with Cirrhosis
住院肝硬化患者的意外提前再入院
- 批准号:
10384144 - 财政年份:2016
- 资助金额:
$ 12.15万 - 项目类别:
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