Training for Future Biotechnology Development

项目摘要 明尼苏达大学的生物技术培训计划已经存在了25年。 该计划汇集了来自生物学，物理学和生物学领域的天才学员和38名教师培训师。 工程学科（8个部门和研究生课程），并创造了一个创新的，交叉， 学科研究和教育奋进。该计划的一个独特之处在于，它不仅跨越了 学科和文化的界限，将学生与生命科学和工程学结合在一起， 背景我们将让生命科学专业的学生接触到应用工程所提供的许多机会 研究问题的原则，同时反过来培养工程专业的学生， 生物系统的分子、细胞和遗传过程。在此续期申请中，我们建议 继续我们在培养未来生物技术科学领导者和创新者方面的成功。我们的新概念 框架将在“从基因组和生物系统通过设计和合成的过程和 产品”。这一新的重点反映了技术和科学的进步， 生物系统工程。我们的培训计划将充分利用学科的广度 由我们的教师代表，为生物技术的这些新方向做好准备。我们有 开发了一个跨学科的课程，通过我们的生物学问题的定量方法教授 核心课程：“生物技术系统的分析、设计和合成”和关于 “基因组到产品”。我们的学员参加讲习班，研讨会和务虚会，以增加交叉- 纪律、职业和专业培训。我们利用我们广泛的校友网络，让学员接触到 “真实的世界”的生物技术，多样化的职业生涯，并准备他们在生物技术的成功职业生涯。实习 举办校友座谈会，让前学员与现任学员交流。实习和公司参观 让学生深入了解工业生物技术。一系列讲习班提供研究行为培训 伦理、研究的可重复性和严格的实验设计。我们继续强调多样性， 我们的培训计划，利用各种机制，促进来自代表性不足群体的受训人员的参与。 开展负责任的研究行为的强制性培训。此外，我们将继续为学员提供 通过我们的国际交流项目，拟议的培训方案将 培养全面的博士工程师和科学家，引领我国未来的生物技术进步 代

PROJECT SUMMARY This Biotechnology training program at the University of Minnesota has been in existence for twenty-five years. This program has brought together gifted trainees and 38 faculty trainers from biological, physical and engineering disciplines (8 departments and graduate programs) and has created an innovative, cross- disciplinary research and educational endeavor. A unique feature of this program is that it crosses not only disciplinary but also cultural boundaries by bringing together students with life sciences and engineering backgrounds. We will expose life science students to the many opportunities offered by applying engineering principles to research questions while conversely training engineering students in the fundamentals of molecular, cellular and genetic processes of biological systems. In this renewal application, we propose to continue our success in training future scientific leaders and innovators in biotechnology. Our new conceptual framework will be on ”From Genomes and Biological Systems via Design and Synthesis to Processes and Products”. This new emphasis reflects the technological and scientific advances made that enable accelerated engineering of biological systems. Our training program will take full advantage of the breadth of disciplines represented by our faculty to prepare our trainees for these new directions in biotechnology. We have developed a cross-disciplinary curriculum that teaches quantitative approaches for biological questions via our core course: “Analysis, Design and Synthesis of Biotechnological Systems” and a summer workshop on “Genomes to Products”. Our trainees participate in workshops, seminars and retreats for additional cross- disciplinary, career and professional training. We leverage our extensive alumni network to expose trainees to “real world” biotechnology, diverse careers and prepare them for successful careers in biotechnology. A trainee organized alumni symposium connects former trainees with current trainees. An internship and company visits give students insight into industrial biotechnology. A series of workshops provide training in research conduct and ethics, research reproducibility and rigorous experimental design. We continue to emphasize diversity in our training program by using mechanisms that facilitate inclusion of trainees from underrepresented groups. Mandatory training for responsible research conduct is in place. Furthermore, we will continue provide trainees with a global perspective through our international exchange program. The proposed training program will produce well rounded PhD engineers and scientists to lead our country’s biotechnology advances in future generations.