Real-time and subjective predictors of vape pod use among young adults with mental health concerns

项目摘要/摘要 电子尼古丁传递系统(“Ends”)在年轻人中的使用在过去几年中急剧增加 过去两年，主要是由于Vape Pods越来越受欢迎，这是一种新型的终端产品， 通过“尼古丁盐”传递尼古丁和调味品。使用量的快速增长令人担忧，因为 潜在的尼古丁依赖；Vape豆荚含有最高浓度的尼古丁末端 市场。虽然对Vape Pod使用的研究仍处于萌芽阶段，但有一种人群可能是唯一易受影响的群体 可使用的包括有精神健康问题的YAS。有心理健康问题的YAS报告使用更多的 烟草产品，包括末端，比他们的同龄人要好。最近的研究发现，抑郁症的症状 焦虑与YAS的终端使用行为呈正相关。心理和心理之间的联系 YA的健康问题和最终使用令人担忧，因为有精神健康问题的个人遭受痛苦 不成比例地受到烟草相关的健康影响，并报告说戒烟比 普通民众。尼古丁依赖在这一人群中尤其成问题，因为尼古丁 导致情绪波动，如抑郁症状和压力，这反过来可能导致更多 在这些人中经常使用。到目前为止，调查与以下因素相关的研究有限 Ends一般使用，Vape Pod特别使用，在有心理健康问题的YA中使用。这样的信息 需要为这一弱势群体制定量身定制的戒烟干预努力提供信息。在……里面 以填补有精神障碍的青少年在理解新型烟草产品使用(即使用Vape Pod)方面的空白 健康问题，这项研究将利用最先进的生态瞬时评估(EMA)和 定性访谈，以调查有症状的YAS中使用Vapod的实时前驱因素 抑郁和/或焦虑。因此，本研究有以下目的：1)评估VAPE的实时预测因子 有抑郁和/或抑郁症状的YAS(n=50)前瞻性研究中的Pod使用情况以及使用模式 使用EMA的焦虑，以及2)探索对VAPE吊舱使用的看法和对未来VAPE的建议 通过定性访谈进行POD停止干预(n=50)。研究的EMA部分将 调查使用的前因，包括社会环境、同时使用物质(其他烟草产品、 酒精、大麻)、情绪、渴望等等。由于EMA无法捕获所有相关构造，因此我们将 用定性访谈补充我们的均线分析。定性访谈将提供重要的见解 以及关于我们EMA调查结果的背景，以及对未来的设计和内容的建议 干预。这项研究直接涉及NIDA的研究重点，包括1)之间的关系 结束使用和共病(即精神健康问题)，以及2)结束使用同时使用其他 烟草制品和其他滥用物质。这项研究也将作为一部小说的基础 对患有抑郁和/或焦虑的YA Vapod使用者进行戒烟干预。

PROJECT SUMMARY/ABSTRACT Electronic Nicotine Delivery Systems (“ENDS”) use among young people has increased dramatically over the past two years, largely due to the increase in popularity of vape pods, a novel type of ENDS product that delivers nicotine and flavorings through “nicotine salts.” This rapid increase in use is alarming given the high potential for nicotine dependence; vape pods contain the highest nicotine concentrations of ENDS on the market. While the research on vape pod use is still nascent, one population that may be uniquely susceptible to use includes YAs with mental health concerns. YAs with mental health concerns report higher use of tobacco products, including ENDS, than their peers. Recent research has found that symptoms of depression and anxiety are positively associated with ENDS use behaviors among YAs. The associations between mental health concerns and ENDS use among YAs is concerning as individuals with mental health concerns suffer disproportionately from tobacco-related health effects and report greater difficulty in quitting as compared to the general population. Nicotine dependence is particularly problematic among this population as nicotine causes fluctuations in mood, such as depressive symptoms and stress, which, in turn, may lead to more frequent use among these individuals. To date, there is limited research investigating factors associated with ENDS use generally, and vape pod use specifically, among YAs with mental health concerns. Such information is needed to inform the development of tailored cessation intervention efforts for this vulnerable population. In order to fill the gap in understanding novel tobacco product use (i.e. vape pod use) among YAs with mental health concerns, this study will utilize state-of-the-science ecological momentary assessment (EMA) and qualitative interviews to investigate real-time antecedents of vape pod use among YAs with symptoms of depression and/or anxiety. Thus, this study has the following aims: 1) to assess real-time predictors of vape pod use, as well as patterns of use, in a prospective study of YAs (n=50) with symptoms of depression and/or anxiety by using EMA, and 2) to explore perceptions of vape pod use and recommendations for future vape pod cessation interventions through the use of qualitative interviews (n=50). The EMA portion of the study will investigate antecedents of use, including social setting, concurrent substance use (other tobacco products, alcohol, and marijuana), mood, craving, among others. As EMA cannot capture all relevant constructs, we will supplement our EMA analyses with qualitative interviews. Qualitative interviews will provide important insights and context regarding our EMA findings, as well as elicit suggestions for the design and content of the future intervention. This research directly addresses NIDA research priorities, including 1) relationships between ENDS use and comorbidities (i.e. mental health concerns), and 2) ENDS use with concurrent use of other tobacco products and other substances of abuse. This study will also serve as the foundation for a novel cessation intervention for YA vape pod users with depression and/or anxiety.