An Experimental Approach to Emotion Regulation: Investigating Rumination, Cognitive Control, and Maladaptive Behaviors.

项目总结/摘要 目的：本研究将采用实验室实验设计，探讨情绪反应和 个体对积极和消极情绪的认知控制。背景：边缘 人格障碍（BPD）是一种情绪和行为失调的障碍，具有重要的医学意义。 15 BPD患者的自杀率约高出200倍 与一般人群相比。16 BPD或亚临床BPD患者经常报告参与广泛的 各种适应不良行为，包括非自杀性自伤（NSSI），暴饮暴食和排泄， 物质滥用，19入店行窃，20鲁莽驾驶，21冲动消费，21开始的论点，22身体 攻击性，23和过度寻求保证。7由于BPD的高风险性， 精神障碍患者在其一生中经常接受多种治疗，因此需要更多的心理健康 比其他精神疾病患者更容易获得更多的资源。25，26意义：了解 情绪失调的发展、潜在结构和机制对于个性化至关重要 治疗开发和实施。更有效的治疗和实施这些 治疗将大大减轻社会负担。创新：以前的研究 而不是比较不同情绪下的情绪反应强度。此外，没有研究调查 积极效价系统与情绪失调，认知控制和参与 适应不良的行为具体目标：本项目的目标是通过以下方式扩展以前的文献： 研究反刍引起的情绪反应与认知控制困难之间的联系。 预期结果：第一，情绪调节困难较大的个体， 影响完成实验室反刍任务。第二，负性情绪反刍任务会导致更多的 认知控制的困难。最后，情绪调节困难的人会表现出一种 在完成中性和积极影响反刍任务后， 在完成中性和积极的沉思后，得分较低的人的积极情感会增加 任务未来方向：该项目将导致个人个性化医疗的发展 有情绪调节障碍的人

PROJECT SUMMARY/ABSTRACT Objective: The study will employ an in-lab experimental design to investigate the emotional reactivity and cognitive control of individuals across several positive and negative emotions. Background: Borderline Personality Disorder (BPD), a disorder of emotional and behavioral dysregulation, has significant medical costs, indicating a high burden to society.15 Suicide is about 200 times higher in individuals with BPD compared to the general population.16 Individuals with BPD or subclinical BPD often report engaging in a wide variety of maladaptive behaviors, including nonsuicidal self-injury (NSSI),17 binge eating and purging,18 substance misuse,19 shoplifting,20 reckless driving,21 impulsive spending,21 starting arguments,22 physical aggression,23 and excessive reassurance seeking.7 Due to the high-risk nature of BPD, individuals with this disorder often engage in multiple treatments throughout their lifetime and therefore require more mental-health resources than do individuals with other psychiatric disorders.25,26 Significance: Understanding the development, underlying constructs, and mechanisms of emotion dysregulation is vital for personalized treatment development and implementation. More effective treatments and implementations of those treatments would result in a significant decrease of the burden to society. Innovation: Previous studies have not compared the intensity of emotional reactions across different emotions. Further, no study has investigated positive valence systems in relation to emotion dysregulation, cognitive control, and engagement of maladaptive behaviors. Specific Aims: The aims of this project are to expand upon previous literature by examining the link between emotional reactivity due to rumination in relation to cognitive control difficulties. Expected Results: First, individuals with greater emotion regulation difficulties will have stronger changes in affect upon completing the in-lab rumination task. Second, negative emotion rumination tasks will lead to more difficulties with cognitive control. Finally, individuals with elevated emotion regulation difficulties will show an increase in negative affect after completing the neutral and positive affect rumination tasks while individuals with lower scores will have an increase in positive affect after completing the neutral and positive rumination tasks. Future Directions: This project will lead to the development of personalized medicine for individuals who have difficulty regulating emotions.