An Experimental Approach to Emotion Regulation: Investigating Rumination, Cognitive Control, and Maladaptive Behaviors.

项目摘要/摘要 目的：本研究将采用实验室内实验设计来考察情绪反应性和 通过几种积极情绪和消极情绪对个体的认知控制。背景：边缘 人格障碍(BPD)是一种情绪和行为失调的疾病，具有重要的医学意义 成本，这表明社会负担很重。15患有自杀症的人自杀率约高出200倍 与一般人群相比，16患有BPD或亚临床BPD的人经常报告参与了广泛的 各种不适应行为，包括非自杀性自残(NSSI)，17暴饮暴食和大小便，18 滥用药物，19起商店盗窃，20起鲁莽驾驶，21起冲动消费，21起争执，22起人身攻击 攻击性，23和过度寻求安慰。7由于BPD的高风险性质，患有这种疾病的人 精神障碍患者一生中经常接受多种治疗，因此需要更多的心理健康。 资源比有其他精神障碍的人更多。25，26意义：理解 情绪失调的发展、潜在结构和机制对个性化至关重要 治疗的制定和实施。对这些问题进行更有效的处理和实施 治疗将大大减轻社会负担。创新：之前的研究已经 而不是比较不同情绪的情绪反应强度。此外，还没有研究调查 正向配价系统与情绪失调、认知控制和参与的关系 适应不良的行为。具体目标：本项目的目标是通过以下方式扩展以前的文献 研究沉思引起的情绪反应与认知控制困难之间的联系。 预期结果：首先，情绪调节困难较大的个体在情绪调节方面的变化会更强 在完成实验室内的沉思任务后会产生影响。第二，消极情绪反省任务会导致更多 认知控制方面的困难。最后，情绪调节困难升高的个体将表现出 在完成中性和积极的反省任务后，负性情绪增加，而个体 得分较低的人在完成中性和积极的沉思后，积极情绪会增加。 任务。未来方向：该项目将引领个人个性化药物的发展 有情绪调节困难的人。

PROJECT SUMMARY/ABSTRACT Objective: The study will employ an in-lab experimental design to investigate the emotional reactivity and cognitive control of individuals across several positive and negative emotions. Background: Borderline Personality Disorder (BPD), a disorder of emotional and behavioral dysregulation, has significant medical costs, indicating a high burden to society.15 Suicide is about 200 times higher in individuals with BPD compared to the general population.16 Individuals with BPD or subclinical BPD often report engaging in a wide variety of maladaptive behaviors, including nonsuicidal self-injury (NSSI),17 binge eating and purging,18 substance misuse,19 shoplifting,20 reckless driving,21 impulsive spending,21 starting arguments,22 physical aggression,23 and excessive reassurance seeking.7 Due to the high-risk nature of BPD, individuals with this disorder often engage in multiple treatments throughout their lifetime and therefore require more mental-health resources than do individuals with other psychiatric disorders.25,26 Significance: Understanding the development, underlying constructs, and mechanisms of emotion dysregulation is vital for personalized treatment development and implementation. More effective treatments and implementations of those treatments would result in a significant decrease of the burden to society. Innovation: Previous studies have not compared the intensity of emotional reactions across different emotions. Further, no study has investigated positive valence systems in relation to emotion dysregulation, cognitive control, and engagement of maladaptive behaviors. Specific Aims: The aims of this project are to expand upon previous literature by examining the link between emotional reactivity due to rumination in relation to cognitive control difficulties. Expected Results: First, individuals with greater emotion regulation difficulties will have stronger changes in affect upon completing the in-lab rumination task. Second, negative emotion rumination tasks will lead to more difficulties with cognitive control. Finally, individuals with elevated emotion regulation difficulties will show an increase in negative affect after completing the neutral and positive affect rumination tasks while individuals with lower scores will have an increase in positive affect after completing the neutral and positive rumination tasks. Future Directions: This project will lead to the development of personalized medicine for individuals who have difficulty regulating emotions.