K-CORE: Curation and Knowledge Management for SPARC

该提案概述了创建 K-CORE 的计划，K-CORE 是 SPARC 的一个新核心，它将提供 SPARC 数据集、知识管理和 SPARC 知识服务的管理 图。后者是一个语义存储，结合了带注释的 SPARC 数据集的信息 根据 SPARC 最小信息标准 (MIS)，具有功能性和解剖性 基于拓扑的自主神经系统（ANS）连接知识。包含在 ANS 是交感神经、副交感神经和肠神经系统，参考 必要时感觉和运动通路。 SPARC 中的技术开发由 SPARC 数据和资源中心 (DRC)，目前由 DAT-CORE 组成，其中规定 数据平台 MAP-CORE，开发 2 维和 3D 地图工具以及基于地图的 GUI， SIM-CORE 是仿真平台。迄今为止，策展和知识 管理职能由 Peter 博士领导的 MAP-CORE 负责 亨特在奥克兰生物信息学研究所工作，并与加州大学圣地亚哥分校分包。然而，这些 服务范围足够广泛且跨领域，应通过单独的机构进行管理 核心。 K-CORE 团队一直为以下领域提供策展和知识管理服务： 自 2018 年开始使用 SPARC，因此对该项目非常熟悉。

This proposal outlines plans for the creation of K-CORE, a new core for SPARC that will provide curation of SPARC datasets, knowledge management and services for the SPARC Knowledge Graph. The latter is a semantic store that combines information on SPARC datasets annotated according to the SPARC Minimal Information Standard (MIS) with functional and anatomical topologically based connectivity knowledge for the autonomic nervous system (ANS). Included in the ANS are the sympathetic, parasympathetic and enteric nervous systems, with reference to sensory and motor pathways as necessary. Technology development in SPARC is provided by the SPARC Data and Resource Center (DRC), currently comprising DAT-CORE, which provisions the data platform, MAP-CORE, which develops 2 and 3D mapping tools and a map-based GUI, and SIM-CORE which fields the simulation platform. To date, the curation and knowledge management functions have been conducted under the purview of MAP-CORE, led by Dr. Peter Hunter at the Auckland Bioinformatics Institute with a subcontract to UCSD. However, these services are sufficiently broad and cross cutting that they should be managed through a separate core. The K-CORE team has been providing curation and knowledge management services for SPARC since 2018 and thus are deeply familiar with the project.