K-CORE: Curation and Knowledge Management for SPARC

该提案概述了创建K-core的计划，K-core是SPARC的一个新核心，将提供 管理SPARC数据集、知识管理和为SPARC知识提供服务 图表。后者是一个语义存储，它结合了有关带注释的SPARC数据集的信息 根据SPARC最小信息标准(MIS)，包括功能和解剖 自主神经系统(ANS)的拓扑学连通性知识。包括在 ANS是指交感神经系统、副交感神经系统和肠道神经系统。 感觉和运动通路视需要而定。SPARC的技术开发由 SPARC数据和资源中心(DRC)，目前由DAT-CORE组成，提供 数据平台MAP-CORE，开发2和3D地图工具和基于地图的图形用户界面， 以及SIM-CORE，它为仿真平台提供了支持。到目前为止，策划人和知识 管理职能一直在彼得博士领导的MAP-CORE的职权范围内进行 亨特在奥克兰生物信息研究所工作，并与加州大学圣地亚哥分校签订了分包合同。然而，这些 服务具有足够的广泛性和交叉性，因此应通过单独的 核心。K-core团队一直为以下项目提供管理和知识管理服务 自2018年以来一直是南太平洋区域合作与合作中心的成员，因此对该项目非常熟悉。

This proposal outlines plans for the creation of K-CORE, a new core for SPARC that will provide curation of SPARC datasets, knowledge management and services for the SPARC Knowledge Graph. The latter is a semantic store that combines information on SPARC datasets annotated according to the SPARC Minimal Information Standard (MIS) with functional and anatomical topologically based connectivity knowledge for the autonomic nervous system (ANS). Included in the ANS are the sympathetic, parasympathetic and enteric nervous systems, with reference to sensory and motor pathways as necessary. Technology development in SPARC is provided by the SPARC Data and Resource Center (DRC), currently comprising DAT-CORE, which provisions the data platform, MAP-CORE, which develops 2 and 3D mapping tools and a map-based GUI, and SIM-CORE which fields the simulation platform. To date, the curation and knowledge management functions have been conducted under the purview of MAP-CORE, led by Dr. Peter Hunter at the Auckland Bioinformatics Institute with a subcontract to UCSD. However, these services are sufficiently broad and cross cutting that they should be managed through a separate core. The K-CORE team has been providing curation and knowledge management services for SPARC since 2018 and thus are deeply familiar with the project.