Synthesizing Best Practice to Accelerate Access to Emerging HIV Prevention Modalities

7.项目总结 该项目是对综合最佳做法的补充，以加速获得新出现的艾滋病毒预防 医疗模式。母项目应用实施科学的方法来支持联邦政府结束 通过发展生物行为基础设施(即，经验上严格的知识， 指导方针、工具)，这将支持扩大有效的PrEP交付方案并促进卫生公平 传播新出现的生物医学艾滋病毒预防战略。本附录旨在进行 协作性、实施性科学研究，既将加强由HRSA资助的卫生领域的EHE活动 中心，并制定一套统一的实践见多识广的计划级指标，以便于比较 跨环境和司法管辖区的实施进展情况。该副刊是与东南地区的合作 艾滋病教育和培训中心(SE AETC)，是一个由HRSA资助的机构，专注于培训、技术 在构成东南地区的八个州支持和实践转型。与 Se AETC，这份补充资料将收集东南部地区五家接受HRSA资助的诊所的数据 根据HRSA 20-091进行艾滋病毒预防，并将这些数据与从十家诊所收集的数据进行比较 通过不同的SE AETC计划获得艾滋病毒预防计划的资金。该补充剂结合了 SE AETC的实践和以社区为中心的专业知识与研究和实施科学 上级项目的专业知识，以实现以下具体目标：(1)规定一套统一的流程 以及与计划实施和评估最相关的结果指标；(2)将一套 统一衡量艾滋病毒预防实施逻辑模型其他关键组成部分的指标；(3)制定 并为这些统一指标试行基于网络的统一数据收集和管理系统 以最低限度减轻合作伙伴诊所站点的负担，实现计划绩效的自动化报告和可视化表示； 以及(4)审查决定因素、实施战略、机制和结果之间的联系 跨合作伙伴临床站点，以便更好地了解如何以及在什么条件下预防艾滋病毒 这些方案最有效地实现了预期的结果。拟议中的项目有可能对 不仅对伙伴临床站点的数据收集和分析产生影响，而且对更大范围的数据统一产生影响 以及NIH和HRSA之间的实施科学合作。我们的项目特别关注 美国东南部地区，该地区在该国新感染艾滋病毒的人数中承担着不成比例的负担。这 实践驱动型实施科学研究对于支持联邦机构在数据驱动、 维持EHE投资影响所需的战略决策过程。

7. PROJECT SUMMARY This project is a supplement to Synthesizing Best Practice to Accelerate Access to Emerging HIV Prevention Modalities. The parent project applies an implementation science approach to support the federal Ending the HIV Epidemic “protect” goal by developing biobehavioral infrastructure (i.e., empirically rigorous knowledge, guidelines, tools) that will support expansion of effective PrEP delivery programs and promote health equity in the dissemination of emerging biomedical HIV prevention strategies. This supplement is designed to conduct collaborative, implementation science research that will both enhance EHE activities at HRSA-funded health centers and develop a unified set of practice-informed, program-level metrics to facilitate comparison of implementation progress across settings and jurisdictions. The supplement is a collaboration with the Southeast AIDS Education and Training Center (SE AETC), which is a HRSA-funded agency focused on training, technical support, and practice transformation in the eight states that comprise the Southeast region. In collaboration with SE AETC, this supplement will collect data from five clinics in the Southeast region that received HRSA funding for HIV prevention under HRSA 20-091, and will compare these data to those collected from ten clinics that receive funding for HIV prevention programs through a different SE AETC initiative. The supplement combines the practice and community-focused expertise of the SE AETC with the research and implementation science expertise of the parent project, in order to achieve the following specific aims: (1) Specify a unified set of process and outcome metrics most relevant for both program implementation and evaluation; (2) Operationalize a set of unified metrics to measure other critical components of HIV prevention implementation logic models; (3) Develop and pilot a web-based, uniform data collection and management system for these unified metrics that would automate reports and visual representation of program performance with minimal burden on partner clinic sites; and (4) Examine the association among determinants, implementation strategies, mechanisms, and outcomes across partner clinical sites in order to better understand how and under what conditions HIV prevention programs most effectively achieve desired outcomes. The proposed project has the potential to have a significant impact, not only on data collection and analysis at the partner clinical sites, but also for larger data harmonization and implementation science collaboration between NIH and HRSA. Our project focuses specifically on the Southeast region of the U.S., which bears a disproportionate burden of new HIV infections in the country. This type of practice-driven implementation science research is vital to supporting federal agencies in the data-driven, strategic decision-making process necessary to sustain the impact of the EHE investment.