Molecular Biophysics Training Program at Stanford

斯坦福大学分子生物物理学培训项目

• 批准号: 10207153
• 负责人: KERWYN C. HUANG
• 金额: $ 58.52万
• 依托单位: STANFORD UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-07-01 至 2026-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10207153
• 关键词: Biophysics; Molecular; Training Programs

Abstract The mission of the Stanford Biophysics Program is to develop students with strong, interdisciplinary, quantitative approaches to meaningful biological problems, while establishing a rigorous atmosphere of inclusion, diversity, and high research conduct and ethics. To meet these goals, trainees participate in coursework, mentored primary research, and other activities designed to enhance their training; together these opportunities prepare graduates for the next step in their careers as part of the STEM workforce. The Program requires graduate-level coursework in physical and biological sciences, participation in seminar series and the retreat, and the development of a high level of proficiency in independent research. Faculty in this interdepartmental predoctoral training program come from 21 departments in the Schools of Humanities and Sciences, Medicine, Engineering, and the Stanford Synchrotron Radiation Laboratory. Student training and research centers on the application of physical and chemical principles and methods to biological problems, as well as the development of new methods. The quantitative relationship between molecular properties and higher-level cell/tissue properties is an increasing focus of the Program, as are emerging areas of quantitative cell and organ biology. Overall, this training program capitalizes on student backgrounds and interests in the physical sciences while fostering creative, collaborative, highly skilled approaches that span biological scales. Trainees are appointed upon admission to Stanford for up to 2 years; the 12 requested slots will generate class sizes of 8-10 through university and externally funded fellowships. There are currently 59 students in the Program (18.6% URMs), most with undergraduate backgrounds in physical science, biochemistry, or engineering. Importantly, our recent efforts have led to diversification of the backgrounds of students in the Biophysics Program through partnerships with a minority-serving institution (UC Merced) and summer research programs that recruit URM students to Stanford. To maximize trainee retention, first-year advising by the Program Director and annual meetings with each student’s thesis committee ensure that a balanced academic program is tailored to the background of each student and that an acceptable level of performance is maintained. Required IDP meetings with the advisor ensure career development and RCR/R&R instruction; the latter is also provided through required coursework including a Statistics class and a variety of elective offerings. Students are heavily involved in program activities, establishing a cohesive community; the Program benefits from high levels of University support and engagement. The fundamental and applied research carried out by our trainees is the cornerstone for developing drugs targeted to specific molecules, for understanding the relationships between environmental stimuli and cell and tissue behavior, and for developing new methods for detecting and treating diseases including cancer and neurological pathlogies.

摘要 斯坦福大学生物物理学项目的使命是培养学生具有强大的，跨学科的， 定量的方法来解决有意义的生物学问题，同时建立一个严格的气氛， 包容性，多样性和高研究行为和道德。为了实现这些目标，学员参加了 课程作业，指导的主要研究，以及其他旨在加强培训的活动;这些 机会准备毕业生在他们的职业生涯的下一步作为STEM劳动力的一部分。程序 需要在物理和生物科学研究生水平的课程，参加系列研讨会和 务虚会，并在独立研究的熟练程度高的发展。教师在此 跨部门的博士前培训计划来自人文学院的21个部门， 科学、医学、工程和斯坦福大学同步辐射实验室。学生培训和 研究的中心是物理和化学原理和方法在生物学问题中的应用， 以及新方法的开发。分子性质与 更高层次的细胞/组织特性是该计划日益关注的焦点，定量分析的新兴领域也是如此。 细胞和器官生物学总的来说，这个培训计划利用学生的背景和兴趣， 物理科学，同时促进创造性，协作，高技能的方法，跨越生物尺度。 学员在被斯坦福大学录取后被任命为最长2年; 12个申请名额将产生 通过大学和外部资助的奖学金，班级规模为8-10人。目前有59名学生在 程序（18.6% URM），大多数具有物理科学，生物化学或 工程.重要的是，我们最近的努力导致了学生背景的多样化， 通过与少数民族服务机构（加州大学默塞德）和夏季研究的伙伴关系生物物理学计划 招收URM学生到斯坦福大学的项目。为了最大限度地留住学员， 项目主任和与每个学生的论文委员会年会确保平衡的学术 该计划是针对每个学生的背景，并认为一个可接受的表现水平是 树立政治意识要求IDP与顾问举行会议，确保职业发展和RCR/R&R指导; 后者也通过必修课程提供，包括统计课和各种选修课 供品。学生积极参与计划活动，建立一个有凝聚力的社区;该计划 受益于大学的高水平支持和参与。进行的基础和应用研究 是开发针对特定分子的药物的基石， 环境刺激与细胞和组织行为之间的关系，以及开发新方法 用于检测和治疗包括癌症和神经病理学在内的疾病。