Training in Mechanisms and Clinical Presentation of Pain

项目总结/摘要 该培训计划的总体目标是培养下一代疼痛研究人员。我们将继续 培训前（每年两名）和博士后（每年两名）研究人员了解疼痛的基本原理， 伤害性信号产生并在整个身体中被调制，并最终整合到大脑中， 感官和情感体验。我们将继续加强通过 该补助金的第一个资助期围绕着较正式的课程和较不正式的培训相结合 经验，旨在提供不仅在疼痛机制和管理坚实的背景， 更多地了解痛苦的负担，但在各种技能的职业发展，包括 使用尖端的方法，网络，向外行和专家观众介绍，以及写作。我们 致力于采用综合方法研究疼痛，这是基于我们的信念，主要是 只有通过多学科方法才能实现这一领域的突破。这是最明显的 通过[1]实验室（横向一体化）和[2]研究人员之间的互动在实践中体现出来， 垂直整合（Vertical Integration）因此，横向和纵向一体化是这一战略的重要组成部分。 培训计划由三个核心要素组成： 1)研究-多学科研究项目不仅受到鼓励，而且受到期待，因为接触临床 疼痛/疼痛相关问题的管理。横向和纵向一体化将通过 项目的选择，由执行委员会的主要指导者根据执行委员会的意见制定， 多学科指导委员会，其中将包括至少一个临床教员之间的三个 四人委员会。 2)理论-学员参加四个学分必修课程： 疼痛，疼痛杂志俱乐部，双周疼痛介绍和疼痛模型的最新研究-基本原理， 测试和解释，以及每月的疼痛研讨会系列，学员与突出的 疼痛研究者这些课程是解决科学严谨性和责任问题的主要场所 以及加强与负责任的研究行为相关的问题。博士后学员将获得 通过参与慢性病患者/家庭教育计划进行额外培训 疼痛诊所，每六周提供一次，作为疼痛患者和家庭的教育资源。 3)实践-学员将接触到评估，诊断和治疗慢性疼痛患者 通过两个（对于博士后来说是三个）主要地点：1）课程的最后三分之一临床机制 疼痛介绍旨在评估特定亚群/方面的诊断和治疗， 疼痛患者（内脏，头痛，老年人等）; 2）在课程疼痛的观点学员阴影疼痛 医生，因为他们采访，诊断和管理疼痛患者;和3）博士后参与 向区域和慢性疼痛研究员介绍教学材料，并参加每半年一次的 疼痛管理论坛为所有研究员（临床和基础）在疼痛相关的培训计划。

Project Summary/Abstract The overarching goal of this training program is to train the next generation of pain researchers. We will continue to train both pre- (two per year) and post-doctoral (two per year) fellows in the fundamental principles of pain, as nociceptive signals arise and are modulated throughout the body and ultimately integrated in the brain to produce the sensory and emotional experience. We will continue to build on the training program developed through the first funding period of this grant around a combination of more formal coursework and less formal training experiences designed to provide not only a solid background in pain mechanisms and management, and a greater appreciation of the burden of pain, but in a variety of skills critical for career development including the use of cutting edge methodology, networking, presentations to both lay and expert audiences, and writing. We are committed to an integrated approach to the study of pain which is based on our belief that major breakthroughs in this field can only be achieved through multidisciplinary approaches. This is most clearly manifest in practice through interactions between [1] laboratories (horizontal integration) and [2] researchers and clinicians (vertical integration). Accordingly, horizontal and vertical integration are essential components of this training program, which consists of three core elements: 1) Research - Multidisciplinary research projects are not only encouraged, but expected, as is exposure to clinical management of pain/pain-related problems. Horizontal and vertical integration will be achieve both through the choice of project, shaped by a primary mentor with input from the executive committee, and through the formation of multidisciplinary mentoring committees which will include at least one clinical faculty member among a three to four-member committee. 2) Theory - Trainees participate in four required for-credit courses: Mechanisms and Clinical Presentation of Pain, Pain Journal Club, bi-weekly Current Research on Pain presentations, and Pain Models – Rationale, Testing and Interpretation, as well as the monthly Pain Seminar Series, where trainees interact with prominent pain researchers. These courses serve as a primary venue to address issues of scientific rigor and responsibility as well as reinforce issues associated with the responsible conduct of research. Post-doctoral trainees will obtain additional training through their participation in the patient/family education program developed by the chronic pain clinic and offered every six weeks as an educational resource for pain patients and families. 3) Practice - Trainees will be exposed to the assessment, diagnosis and treatment of chronic pain patients through two (and for post-docs three) primary venues: 1) The last third of the course Mechanisms of Clinical Presentation of Pain is directed at assessment diagnosis and treatment of specific subpopulations/aspects of pain patients (visceral, headache, geriatric, etc); 2) in the course Pain Perspectives trainees shadow pain physicians as they interview, diagnose and manage pain patients; and 3) Post-docs participate in the presentation of didactic material to Regional and Chronic Pain Fellows, as well as participate in the semi-annual pain management forum for all fellows (clinical and basic) in pain related training programs.