Training in Mechanisms and Clinical Presentation of Pain

项目摘要/摘要 这一培训计划的首要目标是培训下一代疼痛研究人员。我们将继续 对博士后(每年两次)和博士后(每年两次)进行关于疼痛基本原理的培训，例如 伤害性信号产生，并在全身进行调制，最终整合到大脑中，产生 感官和情感体验。我们将继续加强通过 这笔赠款的第一个资助期围绕着更正规的课程和更不正规的培训相结合 设计的经验不仅为疼痛机制和管理提供坚实的背景，而且 更了解痛苦的负担，但对职业发展至关重要的各种技能，包括 使用最先进的方法，建立网络，向外行和专家观众演示，以及写作。我们 致力于疼痛研究的综合方法，这是基于我们的信念，主要 只有通过多学科方法才能在这一领域取得突破。这是最清楚的 通过[1]个实验室(横向一体化)和[2]个研究人员和 临床医生(垂直一体化)。因此，横向和纵向一体化是这方面的重要组成部分。 培训计划，由三个核心要素组成： 1)研究-多学科研究项目不仅受到鼓励，而且是可望的，就像接触临床一样 管理疼痛/与疼痛相关的问题。横向和纵向一体化将通过 项目的选择，由一名主要导师和执行委员会的投入形成，并通过 多学科指导委员会将至少包括三名临床教师中的一名 致四人委员会。 2)理论-实习生参加四门必修学分课程：机制和临床演示 疼痛，疼痛杂志俱乐部，两周一次的关于疼痛陈述和疼痛模型的当前研究-原理， 测试和口译，以及每月疼痛研讨会系列，受训者与杰出人士互动 疼痛研究人员。这些课程是解决科学严谨性和责任感问题的主要场所。 以及加强与负责任的研究行为相关的问题。博士后实习生将获得 通过参与由慢性病患者制定的患者/家庭教育计划进行额外培训 疼痛诊所，每六周提供一次，作为疼痛患者和家属的教育资源。 3)实习生将接触到慢性疼痛患者的评估、诊断和治疗 通过两个(和三个博士后)主要场所：1)最后三分之一的课程机制的临床 疼痛的表现针对特定亚群/方面的评估、诊断和治疗 疼痛患者(内脏、头痛、老年人等)；2)课程中的疼痛透视实习生阴影疼痛 医生在采访、诊断和管理疼痛患者时；3)博士后参与 向区域和慢性疼痛研究员介绍教学材料，并参加半年一次的 为所有与疼痛相关的培训计划的研究员(临床和基础)举办的疼痛管理论坛。

Project Summary/Abstract The overarching goal of this training program is to train the next generation of pain researchers. We will continue to train both pre- (two per year) and post-doctoral (two per year) fellows in the fundamental principles of pain, as nociceptive signals arise and are modulated throughout the body and ultimately integrated in the brain to produce the sensory and emotional experience. We will continue to build on the training program developed through the first funding period of this grant around a combination of more formal coursework and less formal training experiences designed to provide not only a solid background in pain mechanisms and management, and a greater appreciation of the burden of pain, but in a variety of skills critical for career development including the use of cutting edge methodology, networking, presentations to both lay and expert audiences, and writing. We are committed to an integrated approach to the study of pain which is based on our belief that major breakthroughs in this field can only be achieved through multidisciplinary approaches. This is most clearly manifest in practice through interactions between [1] laboratories (horizontal integration) and [2] researchers and clinicians (vertical integration). Accordingly, horizontal and vertical integration are essential components of this training program, which consists of three core elements: 1) Research - Multidisciplinary research projects are not only encouraged, but expected, as is exposure to clinical management of pain/pain-related problems. Horizontal and vertical integration will be achieve both through the choice of project, shaped by a primary mentor with input from the executive committee, and through the formation of multidisciplinary mentoring committees which will include at least one clinical faculty member among a three to four-member committee. 2) Theory - Trainees participate in four required for-credit courses: Mechanisms and Clinical Presentation of Pain, Pain Journal Club, bi-weekly Current Research on Pain presentations, and Pain Models – Rationale, Testing and Interpretation, as well as the monthly Pain Seminar Series, where trainees interact with prominent pain researchers. These courses serve as a primary venue to address issues of scientific rigor and responsibility as well as reinforce issues associated with the responsible conduct of research. Post-doctoral trainees will obtain additional training through their participation in the patient/family education program developed by the chronic pain clinic and offered every six weeks as an educational resource for pain patients and families. 3) Practice - Trainees will be exposed to the assessment, diagnosis and treatment of chronic pain patients through two (and for post-docs three) primary venues: 1) The last third of the course Mechanisms of Clinical Presentation of Pain is directed at assessment diagnosis and treatment of specific subpopulations/aspects of pain patients (visceral, headache, geriatric, etc); 2) in the course Pain Perspectives trainees shadow pain physicians as they interview, diagnose and manage pain patients; and 3) Post-docs participate in the presentation of didactic material to Regional and Chronic Pain Fellows, as well as participate in the semi-annual pain management forum for all fellows (clinical and basic) in pain related training programs.