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Penn mental health AIDS research center

宾夕法尼亚大学心理健康艾滋病研究中心

基本信息

批准号：
10220362
负责人：
DWIGHT L. EVANS
金额：
$ 32.42万
依托单位：
UNIVERSITY OF PENNSYLVANIA
依托单位国家：
美国
项目类别：
财政年份：
2013
资助国家：
美国
起止时间：
2013-06-03 至 2023-01-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/10220362
关键词：
AIDS/HIV problem Acquired Immunodeficiency Syndrome Address Adherence Adult Aging Area Basic Science Behavior Therapy Behavioral Behavioral Mechanisms Behavioral Sciences Biological Biological Sciences Biological Specimen Banks Biology Biometry Botswana Caring Characteristics Child Chronobiology Clinical Cognitive Therapy Collaborations Combined Modality Therapy Communities Complement Continuity of Patient Care Contracts Development Diabetes Mellitus Disease Elderly Evidence based intervention Evidence based practice Faculty Fostering Funding Gender Goals Grant HIV HIV Infections HIV Seropositivity HIV risk Immune System Diseases Immunology Incidence Individual Institutes Institution International Journals Leadership Life Cycle Stages Link Medical Mental Health Mental disorders Mentally Ill Persons Mentors Metabolism Methodology Mission National Institute of Mental Health Neurobiology Obesity Outcome Pediatric Hospitals Pennsylvania Persons Pharmacotherapy Philadelphia Pilot Projects Population Postdoctoral Fellow Pregnant Women Productivity Psychiatry Public Health Public Policy Research Research Personnel Research Priority Research Training Resource Sharing Resources Risk Scientific Inquiry Services Sleep Social Sciences Substance abuse problem Talents Training Translations Treatment outcome Underrepresented Minority United States National Institutes of Health Universities Woman Work antiretroviral therapy base behavioral health circadian collaboratory comorbidity cultural competence data management design health disparity implementation science improved infection risk innovation microbiome next generation novel novel strategies organizational structure pre-doctoral programs psychologic recruit secondary infection senior faculty sex success synergism theories treatment optimization young woman

项目摘要

Overview Abstract/Summary The overarching theme of the Penn Mental Health AIDS Research Center (PMHARC) at the University of Pennsylvania (Penn) and Children's Hospital of Philadelphia (CHOP) is to transform how individuals with comorbid mental illness/AIDS are treated and managed by developing innovative, interdisciplinary, and integrative approaches to optimize psychiatric, behavioral, and medical outcomes and achieving a better understanding of the biological, psychological, and behavioral mechanisms underlying these combined illnesses and treatments. No other center in the U.S. is currently pursuing this explicit focus, making PMHARC unique in the NIMH ARC portfolio. A substantial body of work links psychiatric disorders to acquisition of HIV infection, accelerated immune dysfunction, poor access to HIV care, and poor adherence to antiretroviral treatment once in care. Yet, there is a relative paucity of evidence-based interventions focused on the combined treatment of mental illness/AIDS and related medical co-morbidities, and relatively little work in determining the relationships between mental health treatment and HIV/AIDS disease and understanding the underlying biology. PMHARC will stimulate novel approaches and strategies to address these problems by providing mentoring and resource support for both new and established investigators choosing to study comorbid mental illness/AIDS, in part through innovative pilot studies. PMHARC's leadership has extensive expertise in contemporary pharmacotherapy of mental illness and AIDS, cognitive behavioral treatments, and theory-based behavioral interventions. PMHARC will extend well-established collaborations at Penn and CHOP, including those in the Department of Psychiatry and the CFAR, as well as with the CTSA/CTRC, the Delaney Collaboratory, and community partners in Philadelphia. A unique feature of PMHARC is the collaboration of well- established mental health AIDS researchers, well-established mental health researchers who have not previously studied AIDS, well-established substance abuse AIDS researchers who have not previously studied mental health, and AIDS researchers not previously focused on mental health. PMHARC has an Administrative and Developmental Core, and four Shared Resource Cores.

概述摘要/摘要宾夕法尼亚大学心理健康艾滋病研究中心的主要主题是宾夕法尼亚大学(宾夕法尼亚大学)和费城儿童医院(CHOP)将转变患有精神疾病/艾滋病的患者的治疗和管理方式开发创新、跨学科和综合的方法来优化精神病学、行为和医学结果，并实现对生物学的更好理解，这些联合疾病背后的心理和行为机制治疗。目前，美国没有其他中心在追求这种明确的重点，使 PMHARC在NIMH ARC投资组合中独一无二。大量的工作将精神病学获得艾滋病毒感染的障碍，加速免疫功能障碍，很难获得艾滋病毒护理，以及一旦在护理中坚持抗逆转录病毒治疗就很差。然而，有一种相对稀缺的注重精神疾病/艾滋病和艾滋病综合治疗的循证干预相关的医学合并症，以及确定两者之间的关系的工作相对较少心理健康治疗和艾滋病毒/艾滋病，以及对潜在生物学的了解。 PMHARC将通过以下方式刺激新的方法和战略来解决这些问题为新老调查人员的选择提供指导和资源支持研究精神疾病/艾滋病共病，部分通过创新的先导研究。PMHARC的领导力在当代精神疾病药物治疗方面拥有广泛的专业知识艾滋病、认知行为治疗和基于理论的行为干预。PMHARC将扩展宾夕法尼亚大学和CHOP的良好合作关系，包括在精神病学和CFAR，以及CTSA/CTRC、德莱尼合作实验室和费城的社区合作伙伴。PMHARC的一个独特特点是Well- 著名的心理健康艾滋病研究人员，知名的心理健康研究人员以前没有研究过艾滋病，久负盛名的物质滥用艾滋病研究人员以前没有研究过精神健康，艾滋病研究人员以前也没有关注过心理健康。PMHARC有一个管理和发展核心，有四个共享资源核心。