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Penn mental health AIDS research center

宾夕法尼亚大学心理健康艾滋病研究中心

基本信息

批准号：
10090636
负责人：
DWIGHT L. EVANS
金额：
$ 182.19万
依托单位：
UNIVERSITY OF PENNSYLVANIA
依托单位国家：
美国
项目类别：
财政年份：
2013
资助国家：
美国
起止时间：
2013-06-03 至 2023-01-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/10090636
关键词：
AIDS/HIV problem Acquired Immunodeficiency Syndrome Address Adherence Adult Aging Area Basic Science Behavior Therapy Behavioral Behavioral Mechanisms Behavioral Sciences Biological Biological Sciences Biological Specimen Banks Biology Biometry Botswana Caring Characteristics Child Chronobiology Clinical Cognitive Therapy Collaborations Combined Modality Therapy Communities Complement Continuity of Patient Care Contracts Development Diabetes Mellitus Disease Elderly Evidence based intervention Evidence based practice Faculty Fostering Funding Gender Goals Grant HIV HIV Infections HIV Seropositivity HIV risk Immune System Diseases Immunology Incidence Individual Institutes Institution International Journals Leadership Life Cycle Stages Link Medical Mental Health Mental disorders Mentally Ill Persons Mentors Metabolism Methodology Mission National Institute of Mental Health Neurobiology Obesity Outcome Pediatric Hospitals Pennsylvania Persons Pharmacotherapy Philadelphia Pilot Projects Population Postdoctoral Fellow Pregnant Women Productivity Psychiatry Public Health Public Policy Research Research Personnel Research Priority Research Training Resource Sharing Resources Risk Scientific Inquiry Services Sleep Social Sciences Substance abuse problem Talents Training Translations Treatment outcome Underrepresented Minority United States National Institutes of Health Universities Woman Work antiretroviral therapy base behavioral health circadian collaboratory comorbidity cultural competence data management design health disparity implementation science improved infection risk innovation microbiome next generation novel novel strategies organizational structure pre-doctoral programs psychologic recruit secondary infection senior faculty sex success synergism theories treatment optimization young woman

项目摘要

Overview Abstract/Summary The overarching theme of the Penn Mental Health AIDS Research Center (PMHARC) at the University of Pennsylvania (Penn) and Children's Hospital of Philadelphia (CHOP) is to transform how individuals with comorbid mental illness/AIDS are treated and managed by developing innovative, interdisciplinary, and integrative approaches to optimize psychiatric, behavioral, and medical outcomes and achieving a better understanding of the biological, psychological, and behavioral mechanisms underlying these combined illnesses and treatments. No other center in the U.S. is currently pursuing this explicit focus, making PMHARC unique in the NIMH ARC portfolio. A substantial body of work links psychiatric disorders to acquisition of HIV infection, accelerated immune dysfunction, poor access to HIV care, and poor adherence to antiretroviral treatment once in care. Yet, there is a relative paucity of evidence-based interventions focused on the combined treatment of mental illness/AIDS and related medical co-morbidities, and relatively little work in determining the relationships between mental health treatment and HIV/AIDS disease and understanding the underlying biology. PMHARC will stimulate novel approaches and strategies to address these problems by providing mentoring and resource support for both new and established investigators choosing to study comorbid mental illness/AIDS, in part through innovative pilot studies. PMHARC's leadership has extensive expertise in contemporary pharmacotherapy of mental illness and AIDS, cognitive behavioral treatments, and theory-based behavioral interventions. PMHARC will extend well-established collaborations at Penn and CHOP, including those in the Department of Psychiatry and the CFAR, as well as with the CTSA/CTRC, the Delaney Collaboratory, and community partners in Philadelphia. A unique feature of PMHARC is the collaboration of well- established mental health AIDS researchers, well-established mental health researchers who have not previously studied AIDS, well-established substance abuse AIDS researchers who have not previously studied mental health, and AIDS researchers not previously focused on mental health. PMHARC has an Administrative and Developmental Core, and four Shared Resource Cores.

概述摘要/摘要宾夕法尼亚心理健康艾滋病研究中心（PMHARC）的首要主题是宾夕法尼亚大学（Penn）和费城儿童医院（CHOP）改变患有精神疾病/艾滋病共病的人的治疗和管理方式，开发创新的，跨学科的和综合的方法，以优化精神病学，行为和医疗结果，并更好地了解生物学，这些综合疾病的心理和行为机制，治疗。美国目前没有其他中心追求这一明确的重点， PMHARC是NIMH ARC产品组合中独一无二的。大量的工作将精神病学获得艾滋病毒感染的障碍，加速免疫功能障碍，难以获得艾滋病毒护理，以及接受护理后抗逆转录病毒治疗的依从性差。然而，注重精神疾病/艾滋病综合治疗的循证干预措施，相关的医学共病，以及在确定心理健康治疗和艾滋病毒/艾滋病以及了解潜在的生物学。 PMHARC将鼓励新的方法和战略来解决这些问题，为新的和现有的调查人员提供指导和资源支持，研究精神疾病/艾滋病共病，部分通过创新的试点研究。PMHARC的领导在当代精神疾病药物治疗方面具有广泛的专业知识，艾滋病、认知行为治疗和基于理论的行为干预。PMHARC将扩展在宾夕法尼亚大学和CHOP建立良好的合作，包括那些在该部门精神病学和CFAR，以及CTSA/CTRC，德莱尼合作实验室，费城的社区合作伙伴PMHARC的一个独特之处是良好的合作- 建立心理健康艾滋病研究人员，建立心理健康研究人员谁以前没有研究过艾滋病，公认的药物滥用艾滋病研究人员谁以前没有研究过心理健康，艾滋病研究人员以前没有关注心理健康PMHARC有一个行政和发展核心，四个共享资源核心。