Developmental Research Program

项目摘要/摘要：发展研究方案 范德比尔特-英格拉姆癌症发展研究计划(DRP)的总体目标 胃肠道(GI)癌中心孢子(以下简称VICC GI孢子)是为了鼓励创新 胃肠道肿瘤的翻译研究。DRP将由一名董事(R.Daniel Beuchamp，MD)领导，并将 由高级研究人员组成的发展研究咨询委员会(DRAC)提供支持 范德比尔特和梅哈里医学院(MMC)。民进党领导层与职业生涯有显著的交叉 增强计划(CEP)领导力，鼓励CEP获奖者申请DRP资金并确定 DRP的CEP调查员前景看好。VICC GI孢子DRP将使用一个成熟的和高度 向范德比尔特、MMC和田纳西州立大学的调查人员征集申请的有效程序 大学。处长和民航处处长亦会积极征集目标调查员(女性)的申请。 和代表不足的少数群体)在三个机构内。内部和外部研究人员，包括 GI孢子外部咨询委员会的成员将使用NIH 9分评分来审查申请 系统。评审员将评估科学价值和该项目支持当前GI孢子的可能性 活动，导致外部资金，和/或导致未来的GI孢子项目。我们将特别强调 关于吸引年轻研究人员参与胃肠道癌症研究、高风险/高收益项目以及 整合新兴技术，并将其应用于胃肠道癌症研究。因此，VICC GI孢子DRP将 为新的研究方向提供机会，这些方向可能风险更高，但也有很大的机会 奖励，包括独立资助和可能构成下一次竞争的基础的额外项目 更新。

PROJECT SUMMARY/ABSTRACT: Developmental Research Program The overall objective of the Developmental Research Program (DRP) within the Vanderbilt-Ingram Cancer Center SPORE in Gastrointestinal (GI) Cancer (hereafter, VICC GI SPORE) is to encourage innovative translational research in GI neoplasia. The DRP will be led by a Director (R. Daniel Beauchamp, MD) and will be supported by the Developmental Research Advisory Committee (DRAC) made up of senior investigators at Vanderbilt and Meharry Medical College (MMC). The DRP leadership has significant crossover with the Career Enhancement Program (CEP) leadership to encourage CEP recipients to apply for DRP funding and to identify promising investigators from DRP for the CEP. The VICC GI SPORE DRP will use an established and highly effective procedure to solicit applications from investigators at Vanderbilt, MMC, and Tennessee State University. The Director and the DRAC will also actively solicit applications from targeted investigators (women and underrepresented minorities) within the three institutions. Internal and external researchers, including members of the GI SPORE External Advisory Board, will review applications using the NIH 9-point scoring system. Reviewers will evaluate scientific merit and the likelihood of the project to support current GI SPORE activities, lead to extramural funding, and/or lead to future GI SPORE projects. Special emphasis will be placed on attracting young investigators into GI cancer research, high risk/high gain projects, and projects that incorporate emerging technologies and apply them to GI cancer research. Thus, the VICC GI SPORE DRP will offer the opportunity for new directions of study that may be of higher risk but also have a significant chance for reward, including independent funding and additional projects that may form the basis of the next competing renewal.