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中文摘要
翻译
项目总结/摘要:发展研究项目 Vanderbilt-Ingram癌症发展研究计划(DRP)的总体目标 胃肠道(GI)癌症中心孢子(以下简称VICC GI孢子)是为了鼓励创新 消化道肿瘤的转化研究。DRP将由一名董事(R。医学博士丹尼尔比彻姆)和威尔 由发展研究咨询委员会(Developmental Research Advisory Committee)提供支持,该委员会由高级研究人员组成, 范德比尔特和梅哈里医学院。DRP领导与职业生涯有显著交叉 增强计划(CEP)的领导,以鼓励CEP受助人申请DRP资金,并确定 有前途的研究人员从DRP为CEP。VICC GI SPORE DRP将使用已建立且高度 从范德比尔特、MMC和田纳西州的调查人员那里征求申请的有效程序 大学主任和检察官办公室还将积极征求目标调查人员(妇女)的申请 和代表性不足的少数民族)。内部和外部研究人员,包括 GI SPORE外部顾问委员会的成员将使用NIH 9分评分来审查申请 系统评审员将评估该项目的科学价值和支持当前GI SPORE的可能性 活动,导致校外资金,和/或导致未来的GI孢子项目。将特别强调 吸引年轻的研究人员参与胃肠道癌症研究,高风险/高收益项目,以及 整合新兴技术并将其应用于GI癌症研究。因此,VICC GI SPORE DRP将 为可能具有更高风险的新研究方向提供了机会,但也有很大的机会 奖励,包括独立的资金和额外的项目,可能形成下一个竞争的基础 退款
英文摘要
PROJECT SUMMARY/ABSTRACT: Developmental Research Program The overall objective of the Developmental Research Program (DRP) within the Vanderbilt-Ingram Cancer Center SPORE in Gastrointestinal (GI) Cancer (hereafter, VICC GI SPORE) is to encourage innovative translational research in GI neoplasia. The DRP will be led by a Director (R. Daniel Beauchamp, MD) and will be supported by the Developmental Research Advisory Committee (DRAC) made up of senior investigators at Vanderbilt and Meharry Medical College (MMC). The DRP leadership has significant crossover with the Career Enhancement Program (CEP) leadership to encourage CEP recipients to apply for DRP funding and to identify promising investigators from DRP for the CEP. The VICC GI SPORE DRP will use an established and highly effective procedure to solicit applications from investigators at Vanderbilt, MMC, and Tennessee State University. The Director and the DRAC will also actively solicit applications from targeted investigators (women and underrepresented minorities) within the three institutions. Internal and external researchers, including members of the GI SPORE External Advisory Board, will review applications using the NIH 9-point scoring system. Reviewers will evaluate scientific merit and the likelihood of the project to support current GI SPORE activities, lead to extramural funding, and/or lead to future GI SPORE projects. Special emphasis will be placed on attracting young investigators into GI cancer research, high risk/high gain projects, and projects that incorporate emerging technologies and apply them to GI cancer research. Thus, the VICC GI SPORE DRP will offer the opportunity for new directions of study that may be of higher risk but also have a significant chance for reward, including independent funding and additional projects that may form the basis of the next competing renewal.
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Project 3: Targeting MYC in CRC
Developmental Research Program
SMAD4 regulation of colon epithelial cell inflammatory responses
Project 3: Targeting MYC in CRC
国内基金
海外基金
层出镰刀菌氮代谢调控因子AreA 介导伏马菌素 FB1 生物合成的作用机理
  • 批准号:
    2021JJ40433
  • 项目类别:
    省市级项目
  • 资助金额:
    --
  • 批准年份:
    2021
  • 负责人:
    孙磊
  • 依托单位:
寄主诱导梢腐病菌AreA和CYP51基因沉默增强甘蔗抗病性机制解析
  • 批准号:
    32001603
  • 项目类别:
    青年科学基金项目
  • 资助金额:
    24.0万元
  • 批准年份:
    2020
  • 负责人:
    段真珍
  • 依托单位:
AREA国际经济模型的移植.改进和应用
  • 批准号:
    18870435
  • 项目类别:
    面上项目
  • 资助金额:
    2.0万元
  • 批准年份:
    1988
  • 负责人:
    史树中
  • 依托单位: