Developmental Research Program

项目摘要/摘要：发展研究计划 范德比尔特-英格拉姆癌症中心发展研究计划 (DRP) 的总体目标 胃肠 (GI) 癌症中心 SPORE（以下简称 VICC GI SPORE）旨在鼓励创新 胃肠道肿瘤的转化研究。 DRP 将由一名董事（R. Daniel Beauchamp，医学博士）领导，并将 得到由高级研究人员组成的发展研究咨询委员会 (DRAC) 的支持 范德比尔特和梅哈里医学院 (MMC)。 DRP 领导层与职业有显着交叉 增强计划 (CEP) 领导层鼓励 CEP 接受者申请 DRP 资金并确定 DRP 为 CEP 有前途的研究人员。 VICC GI SPORE DRP 将使用既定且高度 向范德比尔特大学、MMC 和田纳西州立大学的调查人员征求申请的有效程序 大学。主任和 DRAC 还将积极征求目标调查员（女性）的申请 和代表性不足的少数族裔）在三个机构内。内部和外部研究人员，包括 GI SPORE 外部顾问委员会成员将使用 NIH 9 分评分来审查申请 系统。评审员将评估该项目的科学价值和支持当前 GI SPORE 的可能性 活动，带来外部资金，和/或带来未来的 GI SPORE 项目。将特别强调 吸引年轻研究者参与胃肠道癌症研究、高风险/高收益项目以及 整合新兴技术并将其应用于胃肠道癌症研究。因此，VICC GI SPORE DRP 将 提供新的研究方向的机会，这些方向可能具有更高的风险，但也有很大的机会 奖励，包括独立资助和可能构成下一次竞争基础的额外项目 更新。

PROJECT SUMMARY/ABSTRACT: Developmental Research Program The overall objective of the Developmental Research Program (DRP) within the Vanderbilt-Ingram Cancer Center SPORE in Gastrointestinal (GI) Cancer (hereafter, VICC GI SPORE) is to encourage innovative translational research in GI neoplasia. The DRP will be led by a Director (R. Daniel Beauchamp, MD) and will be supported by the Developmental Research Advisory Committee (DRAC) made up of senior investigators at Vanderbilt and Meharry Medical College (MMC). The DRP leadership has significant crossover with the Career Enhancement Program (CEP) leadership to encourage CEP recipients to apply for DRP funding and to identify promising investigators from DRP for the CEP. The VICC GI SPORE DRP will use an established and highly effective procedure to solicit applications from investigators at Vanderbilt, MMC, and Tennessee State University. The Director and the DRAC will also actively solicit applications from targeted investigators (women and underrepresented minorities) within the three institutions. Internal and external researchers, including members of the GI SPORE External Advisory Board, will review applications using the NIH 9-point scoring system. Reviewers will evaluate scientific merit and the likelihood of the project to support current GI SPORE activities, lead to extramural funding, and/or lead to future GI SPORE projects. Special emphasis will be placed on attracting young investigators into GI cancer research, high risk/high gain projects, and projects that incorporate emerging technologies and apply them to GI cancer research. Thus, the VICC GI SPORE DRP will offer the opportunity for new directions of study that may be of higher risk but also have a significant chance for reward, including independent funding and additional projects that may form the basis of the next competing renewal.