Rapid Response and Pilot Research Core

梅森协调和翻译中心的快速反应和试点研究（RRPR）核心 （MCTC）将制定和维持一个有效的程序，促进对新政策的研究， 与阿片类药物使用障碍（OUD）有关的做法，涉及司法的个人，他们的家人，或 社区. RRPR核心有四个具体目标：1）建立一个咨询委员会，包括内部咨询委员会。 2）为快速循环试点研究开发基础设施、政策和程序 申请和赠款资助计划; 3）通过每月和每年定期监测资助计划 报告;和4）创建一个过程，鼓励新的研究项目。Rebekah博士领导的RRPR核心 Hersch是乔治梅森大学（Mason）研究开发副主任， NIDA、指导委员会（SC）、行政部门（Admin）、传播和利益攸关方 参与（D/SE）和研究教育（学习经验推进实践[LEAP]）的核心， 通过、调整和实施申请提交程序。赫希博士有丰富的经验 监督资金的机会，梅森有基础设施，以支持这些举措。RRPR 咨询委员会将由NIDA工作人员、JCOIN组织和外部咨询小组组成，包括 受OUD影响的家庭或个人的代表。确定创新研究，包括时间敏感的 可以迅速获得资金和测试的想法和概念，每年将征集三次提案。 RRPR核心将与管理员和D/SE核心合作，宣传资金公告，并与 广泛的受众，推广新颖的学习理念。将鼓励小型创新研究， 方法，以解决OUD。申请人将被要求确定一个JCOIN调查员一起工作， 包括与方法论和高级分析资源中心的方法学家合作。如果申请人 不隶属于JCOIN，RRPR核心将帮助他们与对他们感兴趣的调查员联系。 项目这是为了鼓励JCOIN社区以外有前途的研究。所有应用程序 将由咨询委员会的三名人员进行审查，他们将沿着提供书面反馈， 一个数字得分;推荐的项目将提交给SC和NIDA的输入和批准。资助 这些项目将限于24个月的项目期和10万美元的直接费用供资。审查进程将 确保每年分配35万美元的试点资金。进度报告摘要 将要求每月提供里程碑、可交付成果、绩效指标和不良事件应对措施。的 RRPR核心将与遇到挑战的资助项目合作，提供一名资深科学家帮助纠正 当然了获资助的计划须于计划完成后三个月内提交最后报告; 研究结果将在网上公布。RRPR核心将是注入NIDA的关键 和JCOIN具有新颖的研究思路，引导新的想法，并围绕OUD建立研究证据。

The Rapid Response and Pilot Research (RRPR) Core of the Mason Coordination and Translation Center (MCTC) will develop and maintain an effective process that facilitates research of emerging policies and practices related to the opioid use disorder (OUD) among justice-involved individuals, their families, or communities. The RRPR Core has four specific aims: 1) establish an Advisory committee, including those within and outside of JCOIN; 2) develop the infrastructure, policies, and procedures for a rapid cycle pilot research application and grant funding program; 3) monitor funded programs through regular monthly and annual reporting; and 4) create a process that encourages novel research projects. The RRPR Core, led by Dr. Rebekah Hersch, Associate Director for Research Development at George Mason University (Mason), will work alongside NIDA, the Steering Committee (SC), the Administration (Admin), the Dissemination and Stakeholder Engagement (D/SE), and the Research Education (Learning Experiences to Advance Practice [LEAP]) Cores to adopt, adapt, and implement an application submission procedure. Dr. Hersch has extensive experience overseeing funding opportunities, and Mason has the infrastructure to support such initiatives. The RRPR Advisory Committee will consist of NIDA staff, JCOIN organizations, and an External Advisory Panel, including representatives of families or individuals affected by OUD. To identify innovative studies, including time-sensitive ideas and concepts that can be rapidly funded and tested, calls for proposals will occur three times per year. The RRPR Core will work with the Admin and D/SE Cores to publicize the funding announcements and reach broad audiences to promote novel study ideas. Small innovative studies will be encouraged, using various methodologies, to address OUD. Applicants will be required to identify a JCOIN investigator to work with, including teaming with a Methodology and Advanced Analytics Resource Center methodologist. If an applicant is not affiliated with JCOIN, the RRPR Core will assist them in connecting with an investigator interested in their project. This is intended to encourage promising research from outside the JCOIN community. All applications will be reviewed by three individuals from the Advisory Committee, who will provide written feedback along with a numerical score; recommended projects will be submitted to SC and NIDA for input and approval. Funded projects will be limited to a 24-month project period and $100,000 of direct cost funding. The review process will be rapid cycle ensuring that pilot funds of $350,000 are allocated each year. Progress reports summarizing milestones, deliverables, performance metrics, and responses to adverse events will be required monthly. The RRPR Core will work with funded projects that encounter challenges by providing a senior scientist to help correct course. Funded projects will be required to submit a final report within three months after project completion; the results of these studies will be available online for the public. The RRPR Core will be essential to infusing NIDA and JCOIN with novel research ideas, piloting new ideas, and building the research evidence around OUD.