Core C: Administrative Core

核心 C：行政核心

• 批准号: 10218081
• 负责人: Cory Abate-Shen
• 金额: $ 13.65万
• 依托单位: COLUMBIA UNIVERSITY HEALTH SCIENCES
• 依托单位国家: 美国
• 财政年份: 2018
• 资助国家: 美国
• 起止时间: 2018-09-11 至 2023-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10218081
• 关键词: Abate; Academic Medical Centers; Area; Bioinformatics; Biometry; Budgets; Cancer Center; Cancer Model; Collaborations; Communication; Conflict (Psychology); Databases; Ensure; Evaluation; Evolution; Feedback; Future; Genomics; Health Insurance Portability and Accountability Act; Human Resources; Individual; Infrastructure; Institution; Investigation; Laboratories; Laboratory Personnel; Leadership; Logistics; Malignant neoplasm of urinary bladder; Memorial Sloan-Kettering Cancer Center; Mission; Modeling; Molecular Analysis; Monitor; Mus; Participant; Pathogenesis; Positioning Attribute; Preparation; Program Reviews; Progress Reports; Reproducibility; Research; Research Personnel; Resolution; Resource Sharing; Resources; Scientist; Secure; Structure; Time; Universities; Work; cloud storage; data management; data resource; data sharing; design; encryption; experience; improved; laboratory experiment; medical schools; meetings; member; molecular pathology; operation; programs; recruit; senior faculty; success; synergism; tumor

Project Summary/Abstract: The Administrative Core will provide coordination and oversight of all activities of the Projects and Cores in this Program, and will maximize interactions and potential synergies among Project Leaders, Core Leaders, and laboratory personnel at the two participating institutions, namely, Columbia University Medical Center (CUMC) and Memorial Sloan Kettering Cancer Center (MSKCC). The major scientific functions of the Core will be to provide expert bioinformatic and biostatistical support for the Projects and other Cores. In addition, to facilitate program integration and effective communication among its various members, the Core will organize monthly meetings composed of two parts: (i) Research presentations, which will include all program participants, as well as relevant Internal Advisory Board members; and (ii) Executive meetings, which will be limited to the Executive Committee (Drs. Abate-Shen, Shen, Solit, and Al-Ahmadie) and members of the Internal Advisory Board. The latter meetings will provide a forum for candid assessment of research progress, oversight of Core utilization, prioritization of resources and objectives, and resolution of potential conflicts. An important function of the Core will be to provide logistical support through management of data and resources, fiscal review and budget analysis, preparation of progress reports, and regulatory compliance. Finally, the Core will organize an annual full-day review of the Program Project by members of the Internal and External Advisory Boards, who will provide detailed feedback on research progress and future directions, as well as advice on program management. This Core will have the following specific aims: (1) To provide bioinformatic and (2) biostatistical support for the Projects, which will be led by co-Investigators, Drs. Barry Taylor (MSKCC) and Tian Zheng (CUMC), respectively. (3) Program management, which will include: (a) Coordination of the overall program by maintaining the organization of the program and establishing mechanisms for effective interaction among its personnel; (b) Data and resource management by promoting effective utilization of Cores A and B, supporting access to secure storage of research presentations and databases, and facilitating data and resource sharing with external laboratories; (c) Review of the Program Project by Internal and External Advisory Boards to evaluate ongoing progress of each Project, review the functionality of the Cores, and provide advice on future research directions. Taken together, the operations of the Administrative Core will ensure the smooth and efficient functioning of the overall Program, as well as planning and oversight for its operations, and will promote the sharing of data and resources within the Program Project as well as with external investigators.

项目摘要/摘要： 行政核心将协调和监督项目的所有活动，并 此计划中的核心，并将最大限度地提高项目负责人、核心 两个参与机构的领导人和实验室人员，即哥伦比亚大学医学院 中心(CUMC)和纪念斯隆·凯特琳癌症中心(MSKCC)。它的主要科学功能 核心将是为项目和其他核心提供生物信息和生物统计方面的专家支持。在……里面 此外，为了促进其各成员之间的计划整合和有效沟通，核心 将组织由两部分组成的每月会议：(I)研究报告，其中将包括所有 方案参与者以及相关的内部咨询委员会成员；和(2)执行会议，其中 将仅限于执行委员会(阿巴特-申博士、沈博士、索利特博士和艾哈迈迪博士)和 内部咨询委员会。后几次会议将为坦率地评估研究进展情况提供一个论坛， 监督核心利用情况、确定资源和目标的优先顺序以及解决潜在冲突。一个 核心的重要职能将是通过管理数据和资源提供后勤支助， 财务审查和预算分析、编写进度报告和遵守法规。最后，核心 将组织内部和外部成员对计划项目进行年度全天审查 咨询委员会，他们将就研究进展和未来方向提供详细反馈，以及 关于项目管理的建议。 该核心将有以下具体目标：(1)提供生物信息学和(2)生物统计学支持 这些项目将由联合调查员巴里·泰勒博士(MSKCC)和田征博士(CUMC)领导， 分别进行了分析。(3)方案管理，其中将包括：(A)通过以下方式协调整个方案 维持方案的组织结构，并建立各方案之间有效互动的机制 人员；(B)数据和资源管理，促进A和B核心的有效利用，支助 访问研究报告和数据库的安全存储，并促进数据和资源共享 与外部实验室合作；(C)内部和外部咨询委员会审查方案项目，以 评估每个项目的持续进展，审查核心的功能，并对未来提供建议 研究方向。总而言之，行政核心的运作将确保 整个计划的有效运作，以及对其运作的规划和监督，并将 促进方案项目内部以及与外部调查人员之间的数据和资源共享。