The RCMI Program in Health Disparities Research at Meharry Medical College

摘要：在我们目前资助的RCMI中心的应用中，我们提出了解决健康差距的建议 多尺度研究：从微观环境到宏观环境。通过机构协作和 支持，我们的应用程序建议继续长期的RCMI支持，使高质量的基本， 消除健康差距的行为、临床研究是我们的长期目标。RHDR@MMC不是 专注于学科或疾病，但强调打破所有尺度上的差异，从蛋白质到 我们所服务的人口的人类生态系统。我们重新设想的研究基础架构核心将提供 与研究项目相关领域的专家技术支持，以及设计、 生物统计学、生物和健康信息学以及交叉培训支持，使该机构的所有研究人员受益。 我们已经召集了一支科学家队伍，包括基础、行为、牙科临床医生、基于人群的、 和Meharry的社区参与的研究人员参与这一努力。我们的目标是： 1.支持四个涉及艾滋病毒/艾滋病、前列腺癌、种族和民族的优秀研究项目 牙周病微生物群的差异和逆境驱动的慢性疼痛推进根本 了解这些健康差距。2)加强核心技术，扩大生物信息学和 支持四个研究项目的生物统计服务，以及所有Meharry研究人员，以 在研究不成比例地影响少数群体和 其他健康差距人群。三、营造有利于新的早期发展的环境 职业调查员通过促进导师网络，加强职业发展活动， 并提供试点资金。4)改善和扩大与社区组织的关系 那个和梅哈里的搭档。5)招募优秀的磁学科学家，激励现有教职员工，贡献力量 我们对包括艾滋病毒-艾滋病在内的服务不足的传染病的癌症的研究能力， 造成少数群体微生物群落差异的差异，以及导致衰弱的社会逆境 非洲裔美国人的慢性疼痛。 我们设计了我们的健康差距研究RCMI计划，通过研究解决健康差距 在影响其服务的社区的疾病中，让该社区参与其解决方案，并创建 为机构科学界及其学术机构提供服务的技术和研究基础设施 和社区合作伙伴。这种协作方法至关重要，因为要找到正确的解决方案 卫生公平方面的差距牵涉到我们所有人。前列腺癌研究是我们RCMI中心的主要研究之一 研究重点。

Abstract: In the application of our currently funded RCMI center, we proposed to address health disparities at multiples scales of research: from micro to macro environments. With institutional collaboration and support, our application proposed to continue the long-term RCMI support of enabling high quality basic, behavioral, and clinical research to eliminate health disparities as our long-term goal. The RHDR@MMC is not discipline or disease focused, but emphasizes the disruption of disparity at all scales, from proteins to the human ecosystems of the populations we serve. Our re-envisioned Research Infrastructure Core will provide expert technical support in areas relevant to the research projects, as well as services such as design, biostatistics, bio and health informatics, and cross-training support to benefit ALL researchers at the institution. We have assembled a cadre of scientists including basic, behavioral, dental clinicians, population-based, and community-engaged researchers at Meharry to participate in this endeavor. Our aims are to: 1. Support four outstanding research projects addressing HIV/AIDS, prostate cancer, racial and ethnic differences in periodontal disease microbiomes, and adversity-driven chronic pain to advance fundamental understanding of these health disparities. 2) Strengthen core technologies and expand bioinformatics and biostatistical services supporting the four research projects, as well as all Meharry research faculty, to increase institutional success in extramural funding studying diseases that disproportionally affect minority and other health disparity populations. 3) Nurture an environment conducive to developing new and early career investigators by facilitating a mentorship network, enhancing professional developmental activities, and providing pilot project funds. 4) Improve and expand relationships with community-based organizations that partner with Meharry. 5) Recruit outstanding magnet scientists to energize current faculty and contribute to our research capacity in cancers of the underserved, infectious diseases including HIV-AIDS, disparity-causing differences in microbiomes of minorities, and societal adversity leading to debilitating chronic pain in African Americans. We designed our RCMI Program in Health Disparities Research to address health disparities through research in diseases that affect the community it serves, engagement of this community in its solutions, and creating technologies and research infrastructure to serve the institutional scientific community and its academic and community partners. This collaborative approach is critical because finding the right answers to address disparities in health equity involves all of us. Prostate cancer research is one of our RCMI Center’s major research focuses.