1/3) MMC, VICC, and TSU: Partners in Eliminating Cancer Disparities

项目总结：总体 基于种族和民族等因素的癌症健康差异是以下因素共同作用的结果 社会经济、环境、行为和生物因素。这些差异影响了癌症的发病率， 患病率、死亡率、存活率、经济负担和筛查率。源远流长、成熟的迈瑞 田纳西州立大学(TSU)范德比尔特-英格拉姆癌症中心(VICC)医学院(MMC) 合作伙伴关系(MVTCP)，继续提供并扩大特殊的癌症研究和培训 环境，以支持不同调查人员解决差异问题的努力。这些努力跨越了 在NCI指定的综合性研究中研究癌症健康差异的决定因素的多学科 癌症中心(VICC)以及加强研究基础设施、能力建设和对两个少数群体的影响- 服务机构(MMC和TSU)。总体而言，在过去20年的伙伴关系中，这些合作 在扩大研究的同时，努力提供强大的基础设施来解决和克服癌症差异 机会、招聘和培训。我们的三合会得益于持续和强大的合作 三个伙伴机构之间的互动，产生了强大的社区和教育成果。 此外，这个三合会的地理位置在田纳西州，一个癌症最高的地区 美国的发病率和死亡率，也为我们的合作伙伴提供了一个独特的机会 对这一地理区域的癌症患者的预后产生积极影响。这一地区继续拥有 肺癌、乳腺癌、前列腺癌和结直肠癌之间存在显著的癌症健康差异。为了达到我们的终极目标 克服癌症差异的目标，同时加强研究影响，总体 此竞争续签申请的目标是：1)增加对传统调查人员的参与- 在资深VICC的协作指导下，启动授予MMC和TSU教职员工的癌症研究项目 教职员工；2)增加由研究员发起的针对癌症的VICC初级教职员工奖的数量 差异；3)招聘、培训和留住早期调查人员，成为癌症健康领域的独立领导者 差异和癌症研究和培训；4)扩大MVTP对国家肿瘤学治疗和培训的参与 干预试验；5)加强MMC和TSU研究的物质和智力基础设施；6) 促进社区组织和学术研究人员之间的伙伴关系，导致假设- 推动研究项目，包括社区健康教育者的参与；7)增加数量 MMC和TSU受训人员从事癌症研究；以及8)提高对癌症研究的认识 少数族裔高中生、本科生、研究生和医学生通过 探索之路计划。

PROJECT SUMMARY: OVERALL Cancer health disparities based on factors such as race and ethnicity are the result of a combination of socioeconomic, environmental, behavioral, and biological factors. These disparities impact cancer incidence, prevalence, mortality, survivorship, financial burden, and screening rates. The long-standing and mature Meharry Medical College (MMC), Vanderbilt-Ingram Cancer Center (VICC), Tennessee State University (TSU) Cancer Partnership (MVTCP), continues to provide and expand upon an exceptional cancer research and training environment to support the efforts of diverse investigators in addressing disparities. These efforts span across multiple disciplines to study the determinants of cancer health disparities at an NCI-designated comprehensive cancer center (VICC) along with enhancing research infrastructure, capacity-building, and impact at two minority- serving institutions (MMC and TSU). Collectively, over the past twenty years of partnership, these collaborative efforts provide a robust infrastructure to address and overcome cancer disparities while expanding research opportunities, recruitment and training. Our Triad has benefited from sustained and strong collaborative interactions between the three partner institutions, resulting in robust community and educational outcomes. Moreover, the geographical placement of this Triad in Tennessee, a region with some of the highest cancer incidence and mortality rates in the United States, also provides a unique opportunity for our Partnership to positively impact outcomes for cancer patients in this geographical region. This region continues to have significant cancer health disparities in lung, breast, prostate, and colorectal cancers. In order to meet our ultimate goals of overcoming cancer disparities while simultaneously strengthening research impact, the overall objectives of this competing renewal application are to: 1) increase the participation in traditional, investigator- initiated cancer research projects awarded to MMC and TSU faculty with collaborative guidance by senior VICC faculty; 2) increase the number of investigator-initiated awards to VICC junior faculty that address cancer disparities; 3) recruit, train and retain early-stage investigators to become independent leaders in cancer health disparities and cancer research and training; 4) expand MVTCP participation in national oncology treatment and interventional trials; 5) strengthen the physical and intellectual infrastructure for research at MMC and TSU; 6) facilitate partnerships between community organizations and academic researchers, leading to hypothesis- driven research projects that include the involvement of a community health educator; 7) increase the number of MMC and TSU trainees engaged in cancer research; and 8) increase awareness of cancer research opportunities and careers for minority high school, undergraduate, graduate and medical students through the Pathway to Discovery program.