MALDI-TOF at Oregon Veterinary Diagnostic Laboratory (OVDL)

俄勒冈州兽医诊断实验室 (OVDL) 的 MALDI-TOF

• 批准号: 10222693
• 负责人: SUSAN J TORNQUIST
• 金额: $ 5.44万
• 依托单位: OREGON STATE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2019
• 资助国家: 美国
• 起止时间: 2019-09-01 至 2024-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10222693
• 关键词: MALDI; TOF; Oregon; Veterinary; Diagnostic

Project Summary/Abstract Mass spectroscopy/matrix-assisted laser desorption/ionization-time of flight (MS MALDI-TOF) systems are now a standard method of bacterial pathogen identification and characterization available at many veterinary diagnostic laboratories. However, the Oregon Veterinary Diagnostic laboratory (OVDL) lacks such a system. OVLD receives a widely varied diagnostic caseload with pathogens from common domestic animals but also wildlife, aquatic and marine species of the Pacific Northwest and the OVDL services are vital to a variety of clients and public health. Traditional bacteriologic diagnostic methods are well-established at the OVDL but a MS-MALDI TOF system would allow more rapid and sometimes accurate information and also supplement/validate traditional methods. The OVDL has in place facilities and intellectual resources to handle a MS-MALDI TOF system. A MS-MALDI TOF system would complement our current methods and allow the OVDL to be fully operational for Vet LIRN projects.

项目总结/摘要 质谱/基质辅助激光解吸/电离飞行时间（MS MALDI-TOF） 系统现在是细菌病原体鉴定和表征的标准方法 许多兽医诊断实验室都有。然而，俄勒冈州兽医诊断 实验室（OVDL）缺乏这样的系统。OVLD接受各种各样的诊断病例， 病原体来自常见的家畜，但也包括野生动物、水生和海洋物种， 太平洋西北地区和OVDL服务对各种客户和公共卫生至关重要。 传统的细菌学诊断方法在OVDL中已经建立，但MS-MALDI TOF系统将允许更快速和有时准确的信息， 补充/验证传统方法。OVDL拥有适当的设施和知识产权 资源来处理MS-MALDI TOF系统。MS-MALDI TOF系统将补充 我们目前的方法，并允许OVDL完全运作的兽医LIRN项目。