Social support to retain adolescents living with HIV in care and improve ART adherence
社会支持以保留艾滋病毒感染青少年并提高抗逆转录病毒疗法的依从性
基本信息
- 批准号:10224012
- 负责人:
- 金额:$ 18.24万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2019
- 资助国家:美国
- 起止时间:2019-08-16 至 2024-07-31
- 项目状态:已结题
- 来源:
- 关键词:AIDS/HIV problemAdherenceAdolescentAdultAfrica South of the SaharaApplications GrantsAppointmentAwardBehavioralCD4 Lymphocyte CountCaringCharacteristicsChildClinicCollaborationsCommunitiesComputersCountryDataDevelopmentDisease ManagementEmotionalEvaluationFocus GroupsFoodFrequenciesFutureGoalsGrantHIVHealth PersonnelHealthcareIncidenceIndividualInformation NetworksInterruptionInterventionInterviewK-Series Research Career ProgramsKnowledgeLinkMalignant NeoplasmsMeasuresMentorsMentorshipMethodsMonitorMorbidity - disease rateNetwork-basedOutcomePathway AnalysisPatient Self-ReportPatientsPharmaceutical PreparationsPilot ProjectsPopulationProviderPublic HealthPublic Health SchoolsRecordsRegimenReportingResearch PersonnelResearch Project GrantsResistanceResourcesRoleSafetySampling StudiesScienceScientistSecureServicesShelter facilitySocial NetworkSocial supportSocietiesSouth AfricaSouth AfricanSpecificityStigmatizationStructureTarget PopulationsTestingTrainingUnited States National Institutes of HealthUniversitiesViralViral Load resultVirusWorkacceptability and feasibilityage groupantiretroviral therapybasebehavioral healthcareercareer developmentdesigndigitalefficacious interventionexperiencefollow-upglobal healthimprovedimproved outcomeinnovationmembermortalitymultidisciplinarypandemic diseaseprematurepsychologicscale upskillssocial structuretheoriestherapy designtherapy developmenttransmission processtreatment adherence
项目摘要
ABSTRACT
Career Goal: I am committed to a career as a behavioral health scientist, integrating psychological science
with public health. My goal is to develop interventions that improve outcomes among adolescents living with
HIV (ALWH) globally. Career Development: This career development award will enhance my analytical skills
and provide specific training in social network analysis, and intervention development, testing, and evaluation.
In this application, I seek to: 1) gain proficiency in the use of social network analysis to inform intervention
development; 2) gain essential skills to develop an interactive, network-based, social support intervention to
retain ALWH in HIV care and improve ART adherence; 3) obtain the training needed to use preliminary data
gathered from this proposal to support a follow up grant proposal for a larger trial aimed at evaluating the
proposed intervention. Research Project: Compared to other age groups, South African ALWH are least
adherent to medication regimens, resulting in elevated rates of HIV-related morbidity, mortality, medication
resistance, and HIV transmission. To improve the outcomes of ALWH, we must identify innovative and
engaging methods to retain them in HIV care. The overall goal of the proposed study is to advance knowledge
on the role of ALWHs’ social networks in their treatment-related outcomes and develop a network-based,
social support intervention to retain them in HIV care and increase ART adherence. First, I will conduct an
egocentric social network analysis of ALWH to determine how key members of their social networks influence
their retention in HIV care and ART adherence. Next, I will conduct qualitative analysis using data from ALWH
and their network members to identify best practices to facilitate intervention acceptability and feasibility. Then,
I will use participatory methods to adapt two network-based interventions to fit the target population and
increase their retention in HIV care and ART adherence. Lastly, I will conduct a pilot study in Cape Town,
South Africa to evaluate the intervention. Mentorship: I will work with a highly accomplished, multidisciplinary
team of experts who will support me over the course of the proposed project. My mentors are Drs. John
Bartlett (Duke University), Michael Sweat (MUSC Center for Global Health), Linda-Gail Bekker (Desmond Tutu
HIV Centre, University of Cape Town), Michael Relf (Duke University), and Carl Latkin (Johns Hopkins
Bloomberg School of Public Health) and my advisors are Drs. Audrey Pettifor (UNC) and Joseph Tucker
(UNC). Future Directions. This award will also inform future NIH grant applications (R34 and R01) to optimize
and evaluate the intervention in a larger study sample.
摘要
职业目标:我致力于作为一名行为健康科学家的职业生涯,
公共卫生。我的目标是制定干预措施,改善青少年生活与
艾滋病毒(ALWH)全球。职业发展:这个职业发展奖将提高我的分析能力
并提供社会网络分析、干预开发、测试和评估方面的具体培训。
在这个应用程序中,我寻求:1)熟练使用社会网络分析,以告知干预
发展; 2)获得基本技能,以发展互动的,基于网络的社会支持干预,
在艾滋病毒护理中保留ALWH并提高ART依从性; 3)获得使用初步数据所需的培训
从这一建议中收集到的信息,以支持一项旨在评估
建议干预。研究项目:与其他年龄组相比,南非ALWH最少
坚持药物治疗,导致艾滋病毒相关发病率、死亡率、药物治疗
耐药性和艾滋病毒传播。为了改善ALWH的成果,我们必须确定创新和
采取各种方法,使他们继续接受艾滋病毒护理。拟议研究的总体目标是促进知识
艾滋病毒/艾滋病患者的社交网络在其治疗相关结果中的作用,并建立一个基于网络的,
社会支助干预措施,使他们继续接受艾滋病毒护理,并增加抗逆转录病毒疗法的坚持。首先,我将进行一次
ALWH的自我中心社会网络分析,以确定其社交网络的关键成员如何影响
他们在艾滋病毒护理和抗逆转录病毒疗法坚持中的保留率。接下来,我将使用ALWH的数据进行定性分析
及其网络成员确定最佳做法,以促进干预措施的可接受性和可行性。然后,
我将使用参与式方法,调整两个基于网络的干预措施,以适应目标人群,
增加他们继续接受艾滋病毒护理和坚持抗逆转录病毒疗法的人数。最后,我将在开普敦进行一项试点研究,
南非评估干预措施。导师制:我将与一个高度成就,多学科
专家团队将在拟议项目的过程中支持我。我的导师是约翰博士
巴特利特(杜克大学)、迈克尔·斯威特(MUSC全球健康中心)、琳达-盖尔·贝克(德斯蒙德·图图)
艾滋病毒中心,开普敦大学)、Michael Relf(杜克大学)和Carl Latkin(约翰·霍普金斯大学)
我的顾问是Audrey Pettifor博士和Joseph Tucker博士
(二)。未来的方向。该奖项还将告知未来的NIH拨款申请(R34和R 01),以优化
并在更大的研究样本中评估干预措施。
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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{{ truncateString('Tiarney D Ritchwood', 18)}}的其他基金
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$ 18.24万 - 项目类别:
Social support to retain adolescents living with HIV in care and improve ART adherence
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