OSU K12 Training Grant in Oncology

项目摘要/摘要 这项提议的目标是指导和培训初级教职研究员实验室和/或临床翻译。 癌症研究。此K12计划的实施以实验室为基础的职业发展 (PhD/DVM/MD)和临床(MD或MD/PhD)肿瘤学不同领域的翻译科学家将确保 训练有素的个人干部，能够跨学科进行交流，推动如何取得新的进步 我们探讨癌症的诊断和治疗。俄亥俄州立大学的K12项目 综合癌症中心(OSUCCC)继续专注于早期药物开发，但现在也扩大了 癌症预防、控制和生存研究。OSUCCC显然致力于研究教育 并为有前途的初级教师提供出色的职业发展和指导机会。这个 血液科、内科肿瘤科、放射肿瘤科和外科肿瘤科都有强大的 不断招聘新的初级教员的项目，以促进我们癌症项目的扩展。 招聘工作还强调将妇女、少数群体和服务不足的群体包括在内，以增加 多样性。这笔K12助学金通过延长研究教育、职业发展和 为有意从事学术研究事业的初级教员提供指导。这是唯一一次OSUCCC培训 该计划仅致力于教师级别的癌症研究职业发展，因此与 俄亥俄州立大学T32培训助学金中的任何一项，主要针对研究员。这一战略确保了培训和培训的连续性 为个人提供成为独立临床或转化型研究人员的结构化路径。质量 K12项目的成功及其在培训癌症研究人员方面的成功，可以从以下职业轨迹中得到证明 过去的学员，他们的论文，资助，临床试验和其他推动新发现的学术活动。 这一计划的持续成功将得到OSUCCC的整体实力和方向的保证，因为 最近的同行评审得分为10(特殊)表明，该K12计划的财政支持由 OSUCCC和不同的司和部门，以及大量的专业知识和资源 在俄亥俄州立大学提供。这个K12项目旨在培养两种类型的调查人员。第一类包括医学博士和/或博士 具有出色的基础科学培训并希望从事与实验室相关的研究的教职员工 在实验治疗、癌症预防、控制和生存方面的应用研究。第二组 包括希望从事实验治疗学和癌症临床研究的医学博士或医学博士/博士教师 预防、控制或生存。培训计划是为每个学员量身定制的，以帮助他们 成功，包括一个强大的评估计划，以评估K12的有效性。它的价值在于 OSU K12计划的最佳演示是由几乎所有目前和过去仍在学术领域的K12学者 作为独立的实验室或临床研究人员向前发展。

Project Summary/Abstract The goal of this proposal is to mentor and train junior faculty investigators in laboratory and/or clinical translational cancer research. Implementation of this K12 program for the career development of laboratory-based (PhD/DVM/MD) and clinical (MD or MD/PhD) translational scientists in diverse areas of oncology will ensure a cadre of highly-trained individuals who can communicate across disciplines to drive new advancements in how we approach cancer diagnosis and management. This K12 program from The Ohio State University Comprehensive Cancer Center (OSUCCC) continues its focus on early drug development, but now also extends to cancer prevention, control and survivorship research. The OSUCCC is clearly dedicated to research education and providing outstanding career development and mentoring opportunities to promising junior faculty. The Divisions of Hematology, Medical Oncology, Radiation Oncology, and Surgical Oncology each have robust programs that are continuously recruiting new junior faculty to facilitate expansion of our cancer program. Recruitment efforts also emphasize the inclusion of women, minorities and underserved groups to increase diversity. This K12 grant fills an important need by extending research education, career development and mentoring to junior faculty interested in establishing academic research careers. It is the only OSUCCC training program dedicated solely to faculty-level career development in cancer research, and thus has no overlap with any of the OSU T32 training grants, which focus on fellows. This strategy ensures continuity in training and provides individuals a structured path to become independent clinical or translational investigators. The quality of this K12 program and its success in training cancer researchers is exemplified by the career trajectories of past trainees, their papers, grants, clinical trials and other scholarly activities that have driven new discoveries. The continued success of this program will be ensured by the overall strength and direction of the OSUCCC, as demonstrated by its recent peer review score of 10 (exceptional), financial support of this K12 program by the OSUCCC and by different Divisions and Departments, and the enormous breadth of expertise and resources available at OSU. This K12 program seeks to train two types of investigators. The first includes MD and/or PhD faculty who have outstanding basic science training and want to pursue laboratory-based investigation related to applied research in experimental therapeutics, cancer prevention, control, and survivorship. The second group includes MD or MD/PhD faculty who want to pursue clinical research in experimental therapeutics and cancer prevention, control, or survivorship. Training plans are tailored to each individual trainee to facilitate their success, with inclusion of a robust evaluation program to assess the effectiveness of the K12. The value of the OSU K12 program is best demonstrated by nearly all of the current and past K12 scholars remaining in academic medicine and moving forward as independent laboratory or clinical investigators.