OSU K12 Training Grant in Oncology

项目总结/摘要 本提案的目标是指导和培训实验室和/或临床翻译领域的初级研究人员 癌症研究。实施K12计划，促进实验室人员的职业发展 (PhD/DVM/MD）和临床（MD或MD/PhD）肿瘤学不同领域的转化科学家将确保 一批训练有素的人员，他们可以跨学科进行沟通，推动在以下方面取得新的进展： 我们致力于癌症的诊断和治疗。俄亥俄州州立大学的K12项目 综合癌症中心（OSUCCC）继续专注于早期药物开发，但现在也扩展了 癌症预防、控制和生存研究。OSUCCC显然致力于研究教育 并为有前途的初级教师提供出色的职业发展和指导机会。的 血液学、内科肿瘤学、放射肿瘤学和外科肿瘤学各部门都有强大的 这些项目正在不断招募新的初级教师，以促进我们癌症项目的扩展。 征聘工作还强调吸收妇女、少数民族和得不到充分服务的群体， 多样性这K12赠款填补了扩大研究教育，职业发展和 指导有兴趣建立学术研究事业的初级教师。OSUCCC培训 该计划专门致力于癌症研究的教师级职业发展，因此与 任何俄勒冈州立大学T32培训赠款，重点是研究员。这一战略确保了培训的连续性， 为个人提供了一个结构化的途径，成为独立的临床或翻译研究者。质量 这个K12计划及其在培训癌症研究人员方面的成功体现在以下职业轨迹中： 过去的学员，他们的论文，赠款，临床试验和其他学术活动，推动了新的发现。 OSUCCC的整体实力和方向将确保该计划的持续成功， 通过其最近的同行评审评分10（特殊），该K12计划的财政支持， OSUCCC和不同的司和部门，以及专业知识和资源的巨大广度 在OSU可用。K12计划旨在培训两种类型的调查人员。第一个包括MD和/或PhD 教师谁拥有优秀的基础科学培训，并希望追求实验室为基础的调查相关 实验疗法、癌症预防、控制和生存的应用研究。第二组 包括医学博士或医学博士/博士教师谁想要追求在实验治疗和癌症的临床研究 预防、控制或生存。培训计划是为每个学员量身定制的，以促进他们的 成功，包括一个强大的评估计划，以评估K12的有效性。的值 俄勒冈州立大学K12计划是最好的证明，几乎所有的当前和过去的K12学者留在学术 作为独立的实验室或临床研究者向前迈进。

Project Summary/Abstract The goal of this proposal is to mentor and train junior faculty investigators in laboratory and/or clinical translational cancer research. Implementation of this K12 program for the career development of laboratory-based (PhD/DVM/MD) and clinical (MD or MD/PhD) translational scientists in diverse areas of oncology will ensure a cadre of highly-trained individuals who can communicate across disciplines to drive new advancements in how we approach cancer diagnosis and management. This K12 program from The Ohio State University Comprehensive Cancer Center (OSUCCC) continues its focus on early drug development, but now also extends to cancer prevention, control and survivorship research. The OSUCCC is clearly dedicated to research education and providing outstanding career development and mentoring opportunities to promising junior faculty. The Divisions of Hematology, Medical Oncology, Radiation Oncology, and Surgical Oncology each have robust programs that are continuously recruiting new junior faculty to facilitate expansion of our cancer program. Recruitment efforts also emphasize the inclusion of women, minorities and underserved groups to increase diversity. This K12 grant fills an important need by extending research education, career development and mentoring to junior faculty interested in establishing academic research careers. It is the only OSUCCC training program dedicated solely to faculty-level career development in cancer research, and thus has no overlap with any of the OSU T32 training grants, which focus on fellows. This strategy ensures continuity in training and provides individuals a structured path to become independent clinical or translational investigators. The quality of this K12 program and its success in training cancer researchers is exemplified by the career trajectories of past trainees, their papers, grants, clinical trials and other scholarly activities that have driven new discoveries. The continued success of this program will be ensured by the overall strength and direction of the OSUCCC, as demonstrated by its recent peer review score of 10 (exceptional), financial support of this K12 program by the OSUCCC and by different Divisions and Departments, and the enormous breadth of expertise and resources available at OSU. This K12 program seeks to train two types of investigators. The first includes MD and/or PhD faculty who have outstanding basic science training and want to pursue laboratory-based investigation related to applied research in experimental therapeutics, cancer prevention, control, and survivorship. The second group includes MD or MD/PhD faculty who want to pursue clinical research in experimental therapeutics and cancer prevention, control, or survivorship. Training plans are tailored to each individual trainee to facilitate their success, with inclusion of a robust evaluation program to assess the effectiveness of the K12. The value of the OSU K12 program is best demonstrated by nearly all of the current and past K12 scholars remaining in academic medicine and moving forward as independent laboratory or clinical investigators.