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2021 Central Nervous System Injury and Repair Gordon Research Conference and Gordon Research Seminar

2021 Central Nervous System Injury and Repair Gordon Research Conference and Gordon Research Seminar
2021中枢神经系统损伤与修复戈登研究大会暨戈登研究研讨会
批准号:
10225691
负责人:
YIMIN ZOU
金额:
$1.2万
依托单位:
依托单位国家:
美国
项目类别:
财政年份:
2021
资助国家:
美国
项目状态:
已结题
起止时间:
2021-07-01 至 2022-06-30

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中文摘要
翻译
这一新的戈登研究会议(GRC)系列的目标是,题为“中枢神经系统损伤和 修复“,以及随之而来的戈登研究研讨会(GRS)将为交流提供一个论坛 在快速发展的损伤领域中,最令人兴奋和尖端的科学数据和新想法, 中枢神经系统的再生和修复,特别是脊髓损伤。脊椎 脊髓损伤是一个重大的医学挑战,因为它使全世界数百万人瘫痪,失去 感觉、心肺、膀胱和性功能障碍以及终生疼痛。尽管多年来 尽管作出了许多努力,但仍然缺乏有效的治疗或治愈方法。这在一定程度上是由于这种疾病的复杂性 除了轴突的损伤外,脊髓损伤还会导致细胞和分子的深刻变化 环境,涉及神经元、神经胶质细胞、免疫细胞等。一个新兴的共识是,组合 针对损伤反应的多个细胞和分子方面的方法将是必要的治疗 脊髓损伤,并诱导功能恢复。因为脊髓是中枢神经系统的重要组成部分 脊髓损伤是一种挑战性的疾病,我们认为目前对脊髓的关注将有助于促进 传播和推进尖端科学。因为中枢神经系统的许多问题 共享脊髓和大脑,目前对脊髓损伤的关注将有助于 一般情况下,中枢神经系统损伤和修复。2021年中枢神经系统损伤与修复GRC 将展示影响伤者的分子、细胞和系统水平变化方面最令人兴奋的工作 脊髓和神经修复。将有9次口头报告,主题涵盖基础科学 到临床翻译。每次演讲都将伴随着充足的时间来查询结果和讨论 对更大的健康社区的影响,包括患者、医疗保健专业人员和政策制定者。 这个互动论坛可以共同加速发现和转化治疗方法,从而 功能恢复。我们的进一步目标是有来自基础和 医生科学家和来自工业界的科学家,以及不同性别、地理位置和 使各年龄段能够广泛传播科学内容。我们将积极敏感地对待 通过向组织和机构传播会议信息,使出席情况多样化的目标 代表不足的个人。也许最激动人心的发展之一将是GRS的引入 这伴随着GRC,这将是该领域未来成功的关键。GRS是一个研讨会 在GRC之前举行,为年轻科学家提供平台讨论他们的研究和 回答其他年轻科学家的实时问题。GRS的目标有两个:推动科学研究 在同行之间进行交流,并由更资深的科学家为年轻科学家提供职业指导 同事们。
英文摘要
The goal of this new Gordon Research Conference (GRC) series, entitled “Central Nervous System Injury and Repair”, together with its accompanying Gordon Research Seminar (GRS), is to provide a forum for the exchange of the most exciting and cutting edge scientific data and novel ideas in the rapidly advancing fields of injury, regeneration, and repair of the central nervous system, with particular emphasis on spinal cord injury. Spinal cord injury is a major medical challenge since it leaves millions of people worldwide paralyzed and with loss of sensation, cardiorespiratory, bladder and sexual dysfunction as well as pain for their lifetime. Despite many years of efforts, an effective treatment or cure is still lacking. This is in part due to the complexity of this disorder where in addition to the damage of axons, spinal cord injury leads to profound changes of the cellular and molecular environment, involving neurons, glia, immune cells, etc. An emerging consensus is that combinatorial approaches targeting multiple cellular and molecular aspects of the injury response will be necessary to treat spinal cord injury and induce functional recovery. As spinal cord is an essential part of the central nervous system and spinal cord injury is a challenging disorder, we think a current focus on the spinal cord will help facilitate communications and advance the cutting-edge science. Because many issues of the central nervous system are shared between the spinal cord and the brain, the current focus on spinal cord injury will benefit the research of central nervous system injury and repair in general. The 2021 Central Nervous System Injury and Repair GRC will feature the most exciting work on the molecular, cellular, and systems-level changes that affect the injured spinal cord and neural repair. There will be 9 sessions of oral presentations ranging in topics from basic science to clinical translation. Each presentation will be accompanied by ample time to query results and discuss the implications for the larger health community, including patients, healthcare professionals, and policy-makers. This interactive forum can collectively accelerate discovery and translation of treatments that will lead to functional recovery. We further aim to have attendance, including oral and poster presenters, from basic and physician scientists and from industry, as well as a breath of diversity across gender, geographical locations and age groups to enable a broad communication of the scientific content. We will be aggressively sensitive to the goal of diversifying attendance by disseminating conference information to organizations and institutions with under-represented individuals. Perhaps one of the most exciting developments will be the introduction of a GRS that accompanies the GRC, which will be essential for the future success of the field. The GRS is a symposium held immediately preceding the GRC that provides a platform for young scientists to discuss their research and respond to real-time queries from other young scientists. The goal of the GRS is two-fold: to fuel scientific communication amongst peers and to provide career mentoring for young scientists by their more senior colleagues.
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会议论文
Characterizing Wnt Signaling Pathways in Axon Guidance
Signaling mechanisms for astrocyte polarization during glial scar formation after spinal cord injury
Combinatorial approaches to maximize axon regeneration after spinal cord injury
Combinatorial approaches to maximize axon regeneration after spinal cord injury
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