Upstate Carolina Consortium - Community Oncology Research Program

项目摘要摘要 北卡罗来纳州联盟NCI社区肿瘤学研究计划(NCORP)集成了3个 共同拥有NCI研究参与历史的附属机构：社区临床 肿瘤学计划(CCOP)1983至2014年和NCORP 2014年至今。 北卡罗来纳州联盟NCORP有48名经验丰富的社区调查员，由3名 合格首席调查员、1名内科肿瘤学家和2名放射肿瘤学家，早期、中期至 高级经验。3个附属研究项目位于社区医院内 服务于南卡罗来纳州北部以及北卡罗来纳州和佐治亚州的邻近地区。纽约州北部 Carolina Consortium NCORP为社会经济困难地区提供服务，该地区有35%的农村人口， 人口老龄化，以及29%的少数民族人口。这些人口长期存在差异， 这一项目将解决癌症的后果。 该项目的目标是通过加快采用以下方法来降低癌症发病率、发病率和死亡率 社区肿瘤学家参与社区实践的研究进展 NCI临床试验中的肿瘤学专家和初级保健医生。 具体目标是：1)在治疗、癌症控制、 预防和生活质量研究；2)开展和支持癌症护理服务的设计 影响患者结局、从业者和医疗保健提供系统的研究；3)确保 筛选和登记NCI精准医学试验的能力，这些试验带来了新的试剂，并希望 癌症患者治疗选择有限；4)加强筛查和获得临床试验 青少年和青壮年人口；5)促进非洲裔美国人和其他 通过社区参与，在我们的集水区参加NCI临床试验的代表性不足的群体； 6)确保高质量的临床研究数据，以支持加速癌症发现；7)支持 培训研究人员和临床研究专业人员以确保有效的临床研究和患者 集中参与；8)通过遵守严格的法规来保护人类受试者 结构和质量保证计划。 该财团拥有实现该项目的经验、能力、机构支持和专业知识。 目标和规定的目标。

Project Summary Abstract The Upstate Carolina Consortium NCI Community Oncology Research Program (NCORP) integrates 3 affiliates who together have a well-established history of NCI research participation: Community Clinical Oncology Program (CCOP) 1983 to 2014 and NCORP 2014 to present. Upstate Carolina Consortium NCORP has 48 experienced and engaged community investigators led by 3 qualified Principal Investigators, 1 medical oncologist and 2 radiation oncologists, with early, mid to senior levels of experience. The 3 affiliate research programs are located within community hospitals serving the upstate of South Carolina and adjacent areas of North Carolina and Georgia. Upstate Carolina Consortium NCORP serves a socioeconomically challenged area with a 35% rural population, aging demographic, and 29% minority population. These populations have longstanding disparities in cancer outcomes which will be addressed by this project. The project goal is to reduce cancer incidence, morbitiy and mortality by accelerating the adoption of research advances into community practices through participation of community oncologists, non- oncology specialists, and primary care physicians in NCI clinical trials. The specific aims are to: 1) Achieve over 400 annual accruals across treatment, cancer control, prevention, and quality of life studies; 2) Conduct and support the design of Cancer Care Delivery Research that impacts patient outcomes, practitioners, and health care delivery systems; 3) Ensure capacity to screen and enroll to NCI Precision Medicine trials which bring novel agents and hope to cancer patients with limited treatment options; 4) Enhance screening and access to clinical trials for Adolescent and Young-Adult populations; 5) Promote the participation of African American and other underrepresented groups in our catchment area to NCI Clinical Trials through community engagement; 6) Ensure high quality clinical research data to support acceleration of cancer discovery; 7) Support Investigators and Clinical Research Professionals training to ensure effective clinical research and patient centered engagement; 8) Protect human subjects through compliance with a rigorous regulatory structure and quality assurance program. The consortium has the experience, capacity, institutional support and expertise to achieve the project goal and stated aims.