Upstate Carolina Consortium - Community Oncology Research Program

卡罗莱纳州北部联盟 - 社区肿瘤​​学研究计划

• 批准号: 10456896
• 负责人: James D Bearden
• 金额: $ 301.97万
• 依托单位: SPARTANBURG REGIONAL MEDICAL CENTER
• 依托单位国家: 美国
• 财政年份: 2019
• 资助国家: 美国
• 起止时间: 2019-09-10 至 2025-07-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10456896
• 关键词: Acceleration; Address; Adolescent and Young Adult; Adopted; Adoption; African American; African American population; Area; Awareness; Cancer Burden; Cancer Control; Cancer Control Research; Cancer Patient; Catchment Area; Clinical Research; Clinical Trials; Communities; Community Clinical Oncology Program; Community Hospitals; Community Participation; Community Physician; Community Practice; Data; Development; Emergency Medicine; Enrollment; Ensure; Facebook; Gastroenterology; Goals; Incidence; Malignant Neoplasms; Medical; Medical Oncologist; Minority Groups; North Carolina; Oncologist; Operative Surgical Procedures; Outcome; Pathologist; Pathology; Patient-Focused Outcomes; Patients; Population; Precision medicine trial; Prevention; Primary Care Physician; Primary Health Care; Principal Investigator; Provider; Quality of life; Radiation; Radiation Oncologist; Radiology Specialty; Recording of previous events; Research; Research Design; Research Personnel; Resources; Rural Population; South Carolina; Specialist; Structure; Surgeon; System; Training; Twitter; Underrepresented Populations; Underserved Population; Urology; aging demographic; base; cancer care; cancer health disparity; cancer prevention; care delivery; community based participatory research; community engagement; community setting; control trial; design; experience; health care delivery; health care disparity; human subject; improved; insight; medical specialist; mortality; multidisciplinary; next generation; novel; patient oriented; precision medicine; programs; protocol development; quality assurance; screening; social media; socioeconomics

Project Summary Abstract The Upstate Carolina Consortium NCI Community Oncology Research Program (NCORP) integrates 3 affiliates who together have a well-established history of NCI research participation: Community Clinical Oncology Program (CCOP) 1983 to 2014 and NCORP 2014 to present. Upstate Carolina Consortium NCORP has 48 experienced and engaged community investigators led by 3 qualified Principal Investigators, 1 medical oncologist and 2 radiation oncologists, with early, mid to senior levels of experience. The 3 affiliate research programs are located within community hospitals serving the upstate of South Carolina and adjacent areas of North Carolina and Georgia. Upstate Carolina Consortium NCORP serves a socioeconomically challenged area with a 35% rural population, aging demographic, and 29% minority population. These populations have longstanding disparities in cancer outcomes which will be addressed by this project. The project goal is to reduce cancer incidence, morbitiy and mortality by accelerating the adoption of research advances into community practices through participation of community oncologists, non- oncology specialists, and primary care physicians in NCI clinical trials. The specific aims are to: 1) Achieve over 400 annual accruals across treatment, cancer control, prevention, and quality of life studies; 2) Conduct and support the design of Cancer Care Delivery Research that impacts patient outcomes, practitioners, and health care delivery systems; 3) Ensure capacity to screen and enroll to NCI Precision Medicine trials which bring novel agents and hope to cancer patients with limited treatment options; 4) Enhance screening and access to clinical trials for Adolescent and Young-Adult populations; 5) Promote the participation of African American and other underrepresented groups in our catchment area to NCI Clinical Trials through community engagement; 6) Ensure high quality clinical research data to support acceleration of cancer discovery; 7) Support Investigators and Clinical Research Professionals training to ensure effective clinical research and patient centered engagement; 8) Protect human subjects through compliance with a rigorous regulatory structure and quality assurance program. The consortium has the experience, capacity, institutional support and expertise to achieve the project goal and stated aims.

项目摘要 上州卡罗莱纳联盟NCI社区肿瘤学研究计划（NCORP）整合了3个 共同拥有良好的NCI研究参与历史的附属机构：社区临床 肿瘤学计划（CCOP）1983年至2014年和NCORP 2014年至今。 上州卡罗莱纳财团NCORP有48名经验丰富，从事社区调查，由3 合格的主要研究者，1名医学肿瘤学家和2名放射肿瘤学家， 高级经验。3个附属研究项目位于社区医院内 服务于南卡罗来纳州的北部以及北卡罗来纳州和格鲁吉亚的邻近地区。州北部 卡罗莱纳财团NCORP服务于一个社会经济困难的地区，农村人口占35%， 人口老龄化和29%的少数民族人口。这些人口在以下方面长期存在差异： 癌症的后果将由该项目解决。 该项目的目标是通过加速采用 通过社区肿瘤学家的参与，研究进展到社区实践中， 肿瘤学专家和NCI临床试验中的初级保健医生。 具体目标是：1）在治疗，癌症控制， 预防和生活质量研究; 2）进行和支持癌症护理交付的设计 影响患者结局、从业人员和医疗保健提供系统的研究; 3）确保 筛选和登记NCI精准医学试验的能力，这些试验带来了新的药物，并希望 治疗选择有限的癌症患者; 4）加强筛查和获得临床试验， 青少年和青年人; 5）促进非裔美国人和其他 在我们的集水区代表性不足的群体通过社区参与NCI临床试验; 6)确保高质量的临床研究数据，以支持加速癌症发现; 7）支持 研究者和临床研究专业人员培训，以确保有效的临床研究和患者 中心参与; 8）通过遵守严格的监管规定保护人类受试者 结构和质量保证方案。 联合体拥有实现该项目的经验、能力、机构支持和专门知识 目的和既定目标。