Administrative Core

管理核心：摘要/总结 行政核心（AC）将为MD安德森提供所有行政和预算支持 癌症中心癌症孢子在胃肠道癌症PI和研究人员，并形成中央“枢纽”， 在SPORE社区内进行富有成效的互动。它由斯科特·科佩茨博士和Anirban Maitra博士共同执导， 并得到了研究项目经理大卫门特博士的支持，这是一个经验丰富的多研究者基金。 管理员和调查员。Kopetz博士和Maitra博士都有监督多名研究者的经验。 包括机构赠款、癌症中心核心赠款计划和对抗癌症赠款的赠款。 协调委员会的总体目标是协调和监督3个项目、2个额外核心项目以及 发展研究（DRP）和职业发展（CEP）计划。AC旨在监控 研究活动，并提供稳定和持续的领导和方向，推进一体化， MD安德森内GI SPORE研究者之间以及院外GI SPORE研究者之间的沟通和协作 我们的合作伙伴机构，特别是约翰霍普金斯大学（JHU）。AC将利用广泛的- 内部和外部咨询委员会的科学、研究和SPORE相关经验， 关键的决策步骤。AC将确保财务管理，包括人员，预算和努力 监督、促进沟通、与患者倡导者沟通、组织会议、手稿 准备、进展和其他报告，提交给NCI和GI SPORE委员会，以及交叉交流 核心和程序。最重要的是确保及时与 NCI转化研究项目主任和工作人员遵守和偏离规定 方案目标。该核心还将监测科学完整性和对所有机构， 州、联邦和NCI法规和要求，以及数据完整性的质量保证，包括 使用新的机构临床试验管理系统变更数据整合计划 （CTMS）代替Redcap，后者提供了驻留在生物标本和病理学中的更多数据链接 核心（核心1）和生物统计学和生物信息学核心（核心2）。AC将负责监督 完成可交付成果的DRP和CEP。咨询委员会还负责召集员工和管理层的例行会议 所有必要的会议。AC还将提高对结肠直肠癌和胰腺癌研究的认识 以及少数民族和服务不足社区的持续需求， 休斯顿和哈里斯县集水区。该核心还将有助于利用和促进翻译GI 癌症研究工作正在进行的校外团体在当地和美国和全球通过这两个 在SPORE框架内进行横向和纵向合作。

ADMINISTRATIVE CORE: Abstract/Summary The Administrative Core (AC) will provide all of the administrative and budgetary support to the MD Anderson Cancer Center Cancer SPORE in Gastrointestinal Cancers PIs and investigators, and form the central “hub” for productive interactions within the SPORE community. It is co-directed by Drs. Scott Kopetz and Anirban Maitra, and supported by a research program manager, Dr. David Menter, an experienced multi-investigator grant administrator and investigator. Both, Dr Kopetz and Dr. Maitra have experience in overseeing multi-investigator grants that include Institutional Grants, Cancer Center Core Grant Programs, and Stand Up to Cancer Grants. The overall goal of the AC will be coordination and monitoring of 3 Projects, 2 additional Cores, as well as the Developmental Research (DRP) and Career Enhancement (CEP) Programs. The AC is designed to monitor research activity and provide stable and continuous leadership and direction that advances integration, communication, and collaboration among GI SPORE investigators within MD Anderson and among extramural institutions, in particular, our partner institution, Johns Hopkins University (JHU). The AC will leverage the wide- ranging scientific, research, and SPORE-related experience of both Internal and External Advisory Boards in critical decision-making steps. The AC will ensure fiscal management, including personnel, budgets, and effort oversight, facilitate communication, interfacing with patient advocates, organization of meetings, manuscript preparation, and progress and other reports to the NCI and GI SPORE committees, and cross-communication of Cores and Programs. Of paramount importance is to ensure timely communication and consultation with the NCI Translational Research Program Director and staff for both adherence and deviations from stated programmatic goals. This Core is to also monitor scientific integrity and overall compliance with all institutional, state, federal, and NCI regulations and requirements, as well as quality assurance for data integrity including a change in the data integration plan with utilization of the new institutional clinical trial management system (CTMS) in lieu of Redcap, which provides greater data linkage residing in the Biospecimen and Pathology Core (Core 1) and Biostatistics and Bioinformatics Core (Core 2). The AC will be responsible for oversight of DRP and CEP for completion of deliverables. The AC also facilitates routine convening of staff and management of all necessary meetings. The AC will also enhanced awareness of colorectal and pancreatic cancer research and patient advocacy in the community as well as ongoing needs of minority and underserved communities in Houston and Harris County catchment area. This core will also help leverage and facilitate translational GI cancer research efforts being conducted by extramural groups locally and in the US and globally through both horizontal and vertical collaborations within the SPORE framework.