Biomolecular Research Core

生物分子研究核心

• 批准号: 10226309
• 负责人: Kenneth A Cornell
• 金额: $ 53.23万
• 依托单位: BOISE STATE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2014
• 资助国家: 美国
• 起止时间: 2014-08-01 至 2024-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10226309
• 关键词: Area; Award; Biochemistry; Bioinformatics; Biological Sciences; Biology; Biomedical Engineering; Biomedical Research; Biometry; Businesses; Cell Nucleus; Centers of Research Excellence; Chemistry; Communities; Computer Analysis; Computer software; Core Facility; Data Analyses; Discipline; Disease Progression; Education; Electrical Engineering; Engineering; Equipment; Experimental Designs; Extracellular Matrix; Fee-for-Service Plans; Fostering; Foundations; Funding; Future; Goals; Growth; Histology; Human Resources; Idaho; Image; Individual; Interdisciplinary Study; Laboratories; Maintenance; Manuscripts; Mass Spectrum Analysis; Medical center; Microscopy; Mission; Natural regeneration; Peer Review; Peer Review Grants; Phase; Physics; Play; Production; Proteomics; Publishing; Recombinant Proteins; Research; Research Activity; Research Infrastructure; Research Personnel; Research Project Grants; Research Support; Research Training; Role; Running; Schools; Science; Senior Scientist; Service delivery model; Services; Students; Therapeutic; Time; Tissues; Training; United States National Institutes of Health; Universities; Veterans; Vision; Visualization; Work; base; career; college; cyber infrastructure; data acquisition; instrumentation; materials science; metabolomics; microscopic imaging; models and simulation; next generation sequencing; operation; programs; repaired; success; therapeutic development; tissue regeneration; tissue repair; transcriptomics

Project Summary – Biomolecular Research Core The overarching goal of the Biomolecular Research Core is to provide critical components of the research infrastructure needed for the success of our biomedical research programs. Access to instrumentation is essential in enabling Boise State University to build a research capability that will support researchers in their endeavor to carry out multidisciplinary research in the area on matrix biology. During COBRE Phase I, the Biomolecular Research Core supported 16 junior investigators within the COBRE in Matrix Biology as well as more established biomedical researchers. Five disciplines across campus are represented among the junior investigator projects including Biological Sciences, Chemistry & Biochemistry, Physics, Material Sciences, Electrical Engineering. Through the services offered to the research community by the BRC, we now have a much larger community of early and mid-career researchers, as well as investigators who have well- established research programs. The total number of annual users increased from 50 in 2014 to 119 in 2017, more than doubling in this time period. Investigators supported by the BRC published 78 peer-reviewed manuscripts that cite the BRC and the COBRE award, and they made more than 700 scientific presentations. The Core facility is equipped for histology, microscopy, and mass spectrometry for proteomics and metabolomics analysis. In partnership with the University of Idaho and Idaho State University, junior investigators will continue to have access to next-generation sequencing instrumentation and technical staff, which will allow them to combine transcriptomics with proteomics. The Core has enhanced current and future NIH-supported research and will continue to do so in Phase II. Establishing and operating the Core is integral to the Center of Biomedical Research Excellence in Matrix Biology and we will continue to work toward sustainable biomedical research growth at Boise State. This facility will be sustained through a business plan based on a fee-for-service model and partnership with departments, schools, and colleges within the university to assure that we are working toward a shared vision and common goals for biomedical research growth that are consistent with the mission of Boise State University.

项目概要-生物分子研究核心 生物分子研究核心的首要目标是提供研究的关键组成部分 我们的生物医学研究计划的成功所需的基础设施。仪器的使用 在使博伊西州立大学建立一个研究能力，将支持研究人员在他们的 奋进在基质生物学领域开展多学科研究。在COBRE第一阶段， 生物分子研究核心支持16名初级研究人员在COBRE在矩阵生物学以及 更成熟的生物医学研究人员。三年级学生中有五门学科 研究项目包括生物科学，化学和生物化学，物理学，材料科学， 电气工程通过BRC向研究界提供的服务，我们现在有一个 更大的早期和中期职业研究人员社区，以及研究人员谁拥有良好的， 建立研究计划。年度用户总数从2014年的50人增加到2017年的119人， 在这段时间里翻了一倍多。在BRC的支持下，研究人员发表了78篇同行评审的 这些手稿引用了BRC和COBRE奖，他们做了700多个科学演讲。 核心设施配备了用于蛋白质组学的组织学、显微镜和质谱分析， 代谢组学分析与爱达荷州大学和爱达荷州州立大学合作， 研究人员将继续使用下一代测序仪器和技术人员， 这将使他们能够将联合收割机转录组学与蛋白质组学结合起来。核心增强了当前和未来 NIH支持的研究，并将在第二阶段继续这样做。建立和运作核心是不可或缺的 生物医学研究中心在矩阵生物学卓越，我们将继续努力， 在博伊西州的可持续生物医学研究增长。该设施将通过一项业务计划予以维持 基于收费服务模式和与大学内的部门，学校和学院的合作关系 确保我们正在努力实现生物医学研究增长的共同愿景和共同目标， 与博伊西州立大学的使命一致。