Core C - Administrative Core

摘要/摘要-行政核心 该计划项目的长期目标是阐明宿主和病毒 影响单纯疱疹病毒与神经元相互作用的机制 要么是溶血性感染，要么是潜伏期。HSV潜伏期是最吸引人的 病毒的生物学特性及其最重要的临床特征，以及 了解HSV潜伏期可能会导致新的治疗方法，甚至是治愈这种疾病的方法 广泛传播的病原体。计划项目的五个不同组成部分--三个 项目和两个核心--进行研究以实现这些目标。这些 科学的组成部分是不同的，但又非常紧密地交织在一起，因此缺乏协调 可能会延缓进展。协调和整合这些科学组成部分，以及 监控进度，项目总监每周主持电话会议并 项目和核心领导以及更初级人员的多次面对面会议 分享结果和假设、计划实验、安排试剂的人员 分享、讨论解释和撰写论文。每年至少召开一次会议 恰逢一个研讨会。内部和外部咨询委员会 提供反馈。项目主管还负责监督财务事务。 行政助理通过安排以下工作来支持项目主管的这些努力 电话会议、会议和旅行，以及帮助运送试剂， 分享数据和手稿，并进行财务监督。行政部门 CORE还将在微生物部建立一个网站，并 允许项目中所有研究人员共享数据的免疫生物学 项目。

Summary/Abstract – Administrative Core The long-term objectives of this Program Project are to elucidate host and viral mechanisms that tilt the interaction of herpes simplex virus (HSV) and neurons either towards lytic infection or towards latency. HSV latency is the most fascinating biological property of the virus and its most important clinical feature, and understanding HSV latency may lead to new therapies or even a cure for this widespread pathogen. Five different components of the program project -- three projects and two cores -- perform the research to address these objectives. These scientific components are distinct, yet very closely interwoven, so lack of coordination could delay progress. To coordinate and integrate these scientific components, and monitor progress, the Program Directors lead weekly phone conferences and multiple face-to-face meetings of the project and core leaders and more junior personnel to share results and hypotheses, plan experiments, arrange reagent sharing, discuss interpretations, and write papers. At least one meeting each year coincides with a symposium. Both an internal and an external advisory committee provide feedback. The Program Directors also oversee financial matters. Administrative assistants support the program directors in these efforts by arranging phone conferences, meetings, and travel, and helping with shipping of reagents, sharing of data and manuscripts, and with financial oversight. The Administrative Core will also establish a website hosted in the Department of Microbiology and Immunobiology that allows data sharing among all the investigators in the Program Project.