Developmental Research Program (DRP)
Developmental Research Program (DRP)
批准号:
10227734
负责人:
PARASKEVI GIANNAKAKOU
金额:
$9.74万
依托单位国家:
美国
项目类别:
财政年份:
2017
资助国家:
美国
项目状态:
已结题
起止时间:
2017-08-30 至 2023-07-31
关键词:
AddressAffectAreaBiomedical ResearchCaliberCancer EtiologyCessation of lifeClinicalClinical ManagementClinical ResearchCollaborationsComplementConsultDataDevelopmentDiagnosisDisciplineDisease ManagementElectronic MailEnsureEnvironmentEvaluationFacultyFundingGoalsHeterogeneityHospitalsHumanIncubatorsInformaticsInfrastructureInstitutesLaboratory ResearchMalignant NeoplasmsMalignant neoplasm of prostateMedicineMemorial Sloan-Kettering Cancer CenterMolecularMonitorNew YorkOralPatient CarePilot ProjectsPlayPresbyterian ChurchPrincipal InvestigatorProceduresProgram Research Project GrantsProgress ReportsPublicationsResearchResearch PersonnelResearch Project GrantsResearch SupportResourcesRoleScheduleScientistStreamSystemTimeTranslational ResearchUnited StatesUnited States National Institutes of HealthUniversitiesWorkanticancer researchcancer diagnosisclinical careclinical practicedesignexperienceflexibilityhigh riskimprovedinnovationmalemeetingsmembermennovelprecision medicineprogramssuccess
中文摘要
发展研究项目总结
英文摘要
DEVELOPMENTAL RESEARCH PROGRAM SUMMARY
The Developmental Research Program (DRP) will act as an incubator for high-risk/high-gain and novel
collaborative projects within the Weill Cornell Medicine (WCM) SPORE in Prostate Cancer (PCa). Each DRP
project will require one-to-two years of development time and funds to facilitate compelling preliminary data.
To this end, the WCM SPORE will establish a DRP that will address 1) develop infrastructure to solicit
competitive developmental projects across the Weill Cornell and Columbia University campuses, 2) facilitate
evaluation of proposals for the DRP, and 3) implement procedures for a developmental project to replace an
existing major SPORE Project. Led by Dr. Lewis Cantley, Dr. David Nanus, and Dr. Paraskevi Giannakakou,
the DRP for the WCM SPORE will distribute announcements using broadcast email systems in place at both
universities to solicit highly competitive pilot project proposals spanning wide areas of disciplines beyond
traditional biomedical research. We anticipate populating the DRP with up to two new pilot projects per year
and will support up to four (4) pilot projects concurrently. The DRP will be also be used as pipeline for
competitive developmental projects to fill whichever vacant slots for major SPORE Projects. The SPORE
Principal Investigator, Internal Advisory Board (IAB) and DRP co-Directors will make use of regularly
scheduled meetings to ensure major projects are evaluated at least twice a year. Of note, the External
Advisory Board (EAB) will be consulted annually on projects related to the DRP. Regular bi-monthly meetings
and additional closed meetings with Co-Leaders of the major Projects and developmental projects will help
determine if and when implementation of a new major Project is required. The DRP is a vital aspect of a highly
productive SPORE program to ensure innovative developmental projects are available to replace major
projects and to advance the SPORE's overall translational goals.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
Mechanistic Insights Underlying ERG-induced Taxane Resistance in Castration-Resis
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批准号:9440347
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项目类别:
-
资助金额:$42.89万
-
财政年份:2014
-
负责人:PARASKEVI GIANNAKAKOU
-
依托单位:
Microtubule-Regulated RNA Translation: Implications for Taxane Chemotherapy
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批准号:8655336
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项目类别:
-
资助金额:$36.11万
-
财政年份:2014
-
负责人:PARASKEVI GIANNAKAKOU
-
依托单位:
Mechanistic Insights Underlying ERG-induced Taxane Resistance in Castration-Resis
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批准号:8704646
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项目类别:
-
资助金额:$42.89万
-
财政年份:2014
-
负责人:PARASKEVI GIANNAKAKOU
-
依托单位:
Mechanistic Insights Underlying ERG-induced Taxane Resistance in Castration-Resis
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批准号:8837583
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项目类别:
-
资助金额:$42.89万
-
财政年份:2014
-
负责人:PARASKEVI GIANNAKAKOU
-
依托单位:
Mechanistic Insights Underlying ERG-induced Taxane Resistance in Castration-Resis
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批准号:9017961
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项目类别:
-
资助金额:$42.89万
-
财政年份:2014
-
负责人:PARASKEVI GIANNAKAKOU
-
依托单位:
Microtubule-Regulated RNA Translation: Implications for Taxane Chemotherapy
-
批准号:8842107
-
项目类别:
-
资助金额:$35.82万
-
财政年份:2014
-
负责人:PARASKEVI GIANNAKAKOU
-
依托单位:
Microtubule dependent AR signaling predicts taxane sensitivity
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批准号:8469008
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项目类别:
-
资助金额:$31.97万
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财政年份:2009
-
负责人:PARASKEVI GIANNAKAKOU
-
依托单位:
Microtubule dependent AR signaling predicts taxane sensitivity
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批准号:8266465
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项目类别:
-
资助金额:$34.02万
-
财政年份:2009
-
负责人:PARASKEVI GIANNAKAKOU
-
依托单位:
Microtubule dependent AR signaling predicts taxane sensitivity
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批准号:7736273
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项目类别:
-
资助金额:$35.07万
-
财政年份:2009
-
负责人:PARASKEVI GIANNAKAKOU
-
依托单位:
Microtubule dependent AR signaling predicts taxane sensitivity
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批准号:8073086
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项目类别:
-
资助金额:$34.02万
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财政年份:2009
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负责人:PARASKEVI GIANNAKAKOU
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依托单位:
Targeting Microtubules and HDAC6 in NSCLC
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批准号:7109525
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项目类别:
-
资助金额:$21.63万
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财政年份:2006
-
负责人:PARASKEVI GIANNAKAKOU
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依托单位:
Microtubule-targeting and regulation of HIF-1
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批准号:7184914
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项目类别:
-
资助金额:$28.09万
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财政年份:2005
-
负责人:PARASKEVI GIANNAKAKOU
-
依托单位:
Microtubule-targeting and regulation of HIF-1
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批准号:7595232
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项目类别:
-
资助金额:$28.31万
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财政年份:2005
-
负责人:PARASKEVI GIANNAKAKOU
-
依托单位:
Microtubule-targeting and regulation of HIF-1
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批准号:7233248
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项目类别:
-
资助金额:$28.31万
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财政年份:2005
-
负责人:PARASKEVI GIANNAKAKOU
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依托单位:
Microtubule-targeting and regulation of HIF-1
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批准号:7390224
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项目类别:
-
资助金额:$28.31万
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财政年份:2005
-
负责人:PARASKEVI GIANNAKAKOU
-
依托单位:
Microtubule-targeting and regulation of HIF-1
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批准号:7046865
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项目类别:
-
资助金额:$29.16万
-
财政年份:2005
-
负责人:PARASKEVI GIANNAKAKOU
-
依托单位:
Antitubulin drugs: Mechanisms of action and resistance
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批准号:7027635
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项目类别:
-
资助金额:$28.35万
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财政年份:2003
-
负责人:PARASKEVI GIANNAKAKOU
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依托单位:
Antitubulin drugs: Mechanisms of action and resistance
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批准号:6598337
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项目类别:
-
资助金额:$27.06万
-
财政年份:2003
-
负责人:PARASKEVI GIANNAKAKOU
-
依托单位:
Antitubulin drugs: Mechanisms of action and resistance
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批准号:7158489
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项目类别:
-
资助金额:$29.2万
-
财政年份:2003
-
负责人:PARASKEVI GIANNAKAKOU
-
依托单位:
Antitubulin drugs: Mechanisms of action and resistance
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批准号:6919883
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项目类别:
-
资助金额:$27.06万
-
财政年份:2003
-
负责人:PARASKEVI GIANNAKAKOU
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依托单位:
海外基金