Uganda International Center for Excellence in Research

新出现/再出现的人畜共患疾病是一个重大的全球卫生问题。将乌干达节肢动物/病媒种群的综合病原体监测与区域和国际一级的公共卫生监测联系起来，将对东非的人类和动物健康以及整个“一个世界一个健康”概念作出重要贡献。将重点关注可能导致人类、野生动物和牲畜患病的啮齿动物传播的病原体。更全面地了解已知和未知啮齿动物传播的人畜共患病病原体的生态，对于评估地方和全球人类和动物健康的风险至关重要。

Emerging/re-emerging zoonotic diseases are a major global health problem. Linking comprehensive pathogen surveillance of arthropod/vector populations in Uganda with public health surveillance at the regional and international level will make an important contribution to human and animal health in East Africa and the One World One Health concept in general. There will be a focus on rodent-borne pathogens potentially causing disease in humans, wildlife and livestock. A more comprehensive understanding of the ecology of known and unknown rodent-borne zoonotic pathogens is essential for a risk assessment for local and global human and animal health. The establishment of emerging/re-emerging virus program on the campus of the Uganda Virus Research Institute (UVRI), Entebbe, Uganda is ongoing. Rakai is no longer considered as a second program site. We have procured most of the necessary equipment for the UVRI site; further equipment will be purchased when needed. Over the previous and current funding period we have refined molecular and serological detection assays for several pathogens including arenaviruses, bunyaviruses, coronaviruses filoviruses, and flaviviruses. The ongoing SARS-CoV-2 pandemic and several ongoing outbreaks, such as the Ebola in the Democratic Republic of the Congo (DRC) and the ongoing Lassa fever outbreak in Nigeria, have delayed this project multiple times. Nevertheless, we continue to advance our molecular and serological assays that will be deployed to Uganda as soon as the lab space at UVRI is available and functional. Field work is now scheduled to start in the upcoming fiscal year.